Search Results - "Gonzaga, Natália A"

Quercetin decreases the activity of matrix metalloproteinase-2 and ameliorates vascular remodeling in renovascular hypertension by Pereira, Sherliane C., Parente, Juliana M., Belo, Vanessa A., Mendes, Atlante S., Gonzaga, Natália A., do Vale, Gabriel T., Ceron, Carla S., Tanus-Santos, José Eduardo, Tirapelli, Carlos R., Castro, Michele M.

“…Increased activity of matrix metalloproteinase (MMP)-2 is observed in aortas of different models of hypertension, and its activation is directly mediated by…”
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Melatonin reverses the loss of the anticontractile effect of perivascular adipose tissue in obese rats by Gonzaga, Natália A., Awata, Wanessa M. C., Ficher, Sabrina P., Assis, Victor O., Alves, Juliano V., Tostes, Rita C., Tirapelli, Carlos R.

“…Perivascular adipose tissue (PVAT) undergoes functional changes in obesity. Increased oxidative stress is a central mechanism whereby obesity induces loss of…”
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Nebivolol prevents ethanol-induced reactive oxygen species generation and lipoperoxidation in the rat kidney by regulating NADPH oxidase activation and expression by do Vale, Gabriel T., Gonzaga, Natália A., Simplicio, Janaina A., Tirapelli, Carlos R.

“…We studied whether the β1-adrenergic antagonist nebivolol would prevent ethanol-induced reactive oxygen species generation and lipoperoxidation in the rat…”
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Perivascular adipose tissue contributes to lethal sepsis-induced vasoplegia in rats by Awata, Wanessa M.C., Gonzaga, Natália A., Borges, Vanessa F., Silva, Carla B.P., Tanus-Santos, José E., Cunha, Fernando Q., Tirapelli, Carlos R.

“…It is well established that sepsis induces vascular hyporesponsiveness to vasoconstrictors. Perivascular adipose tissue (PVAT) displays anti-contractile action…”
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Nebivolol prevents vascular oxidative stress and hypertension in rats chronically treated with ethanol by do Vale, Gabriel T., Simplicio, Janaina A., Gonzaga, Natália A., Yokota, Rodrigo, Ribeiro, Amanda A., Casarini, Dulce E., de Martinis, Bruno S., Tirapelli, Carlos R.

“…Chronic ethanol consumption is associated with hypertension and atherosclerosis. Vascular oxidative stress is described as an important mechanism whereby…”
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Interleukin-10 limits the initial steps of the cardiorenal damage induced by ethanol consumption by Silva, Carla B.P., Gómez, Julieth P.S., do Vale, Gabriel T., Simplicio, Janaina A., Gonzaga, Natália A., Tirapelli, Carlos R.

“…Reactive oxygen species (ROS) and pro-inflammatory cytokines play a critical role in organ damage induced by ethanol consumption. Interleukin (IL)-10 maintain…”
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Perivascular adipose tissue protects against the vascular dysfunction induced by acute ethanol intake: Role of hydrogen peroxide by Gonzaga, Natália A., Awata, Wanessa M.C., do Vale, Gabriel T., Marchi, Katia C., Muniz, Jaqueline J., Tanus-Santos, Jose E., Tirapelli, Carlos R.

“…We investigated the consequences of acute ethanol intake on the anti-contractile effect of perivascular adipose tissue (PVAT). The effects of a single dose of…”
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Mechanisms underlying vascular hypocontractility induced by ethanol withdrawal: Role of cyclooxygenase 2-derived prostacyclin by Gonzaga, Natália A., Awata, Wanessa M.C., Tanus-Santos, Jose E., Padovan, Júlio C., Tirapelli, Carlos R.

“…The effects on the vasculature produced by ethanol withdrawal include both vasodilatation and hypocontractility, although a detailed biochemical understanding…”
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Chronic ethanol consumption induces micturition dysfunction and alters the oxidative state of the urinary bladder by do Vale, Gabriel T, Sousa, Arthur H, Gonzaga, Natália A, de Oliveira, Mariana G, Justo, Alberto F O, Alexandre, Eduardo C, Tanus-Santos, Jose E, Antunes, Edson, Tirapelli, Carlos R

“…Oxidative stress is pointed out as a major mechanism by which ethanol induces functional and structural changes in distinctive tissues. We evaluated whether…”
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Ethanol Withdrawal Alters the Oxidative State of the Heart Through AT1-Dependent Mechanisms by Assis, Victor O, Gonzaga, Natália A, Silva, Carla B P, Pereira, Lucas C, Padovan, Cláudia M, Tirapelli, Carlos R

“…Abstract Aims We investigated the cardiac effects of ethanol withdrawal and the possible role of AT1 receptors in such response. Methods Male Wistar rats were…”
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Nebivolol Prevents Up-Regulation of Nox2/NADPH Oxidase and Lipoperoxidation in the Early Stages of Ethanol-Induced Cardiac Toxicity by do Vale, Gabriel T., da Silva, Carla B. P., Sousa, Arthur H., Gonzaga, Natália A., Parente, Juliana M., Araújo, Katiúscia M., Castro, Michele M., Tirapelli, Carlos R.

“…Changes in redox state are described in the early stages of ethanol-induced cardiac toxicity. Here, we evaluated whether nebivolol would abrogate…”
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Pharmacological characterization of the mechanisms underlying the vascular effects of succinate by Leite, Letícia N., Gonzaga, Natália A., Simplicio, Janaina A., do Vale, Gabriel T., Carballido, José M., Alves-Filho, José C., Tirapelli, Carlos R.

“…We investigated the mechanisms underlying the vascular effects of succinate. Vascular reactivity experiments were performed in aortic rings isolated from male…”
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Treatment with nitrite prevents reactive oxygen species generation in the corpora cavernosa and restores intracavernosal pressure in hypertensive rats by Gonzaga, Natália A., do Vale, Gabriel T., da Silva, Carla B.P., Pinheiro, Lucas C., Leite, Letícia N., Carneiro, Fernando S., Tanus-Santos, José E., Tirapelli, Carlos R.

“…Hypertension is a risk factor for erectile dysfunction (ED) and both conditions are associated with oxidative stress. Given that nitrite is described to…”
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Mechanisms underlying sodium nitroprusside-induced tolerance in the mouse aorta: Role of ROS and cyclooxygenase-derived prostanoids by Diniz, Mariana C., Olivon, Vania C., Tavares, Lívia D., Simplicio, Janaina A., Gonzaga, Natália A., de Souza, Daniele G., Bendhack, Lusiane M., Tirapelli, Carlos R., Bonaventura, Daniella

“…To determine the role of reactive oxygen species (ROS) on sodium nitroprusside (SNP)-induced tolerance. Additionally, we evaluated the role of ROS on NF-κB…”
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Pharmacological characterisation of the mechanisms underlying the relaxant effect of adrenomedullin in the rat carotid artery by Passaglia, Patrícia, Gonzaga, Natália A., Tirapelli, Daniela P.C., Tirapelli, Luis F., Tirapelli, Carlos R.

“…Objectives We investigated the mechanisms underlying the relaxant effect of adrenomedullin (AM) in the rat carotid artery and verified the expression of AM…”
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Tumor necrosis factor-α receptor 1 contributes to ethanol-induced vascular reactive oxygen species generation and hypertension by Simplicio, Janaina A, Gonzaga, Natália A, Nakashima, Marcelo A, De Martinis, Bruno S, Cunha, Thiago M, Tirapelli, Luis F, Tirapelli, Carlos R

“…We evaluated the contribution of tumor necrosis factor-α receptor 1 (TNFR1) to ethanol-induced hypertension and vascular oxidative stress and the possible role…”
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Reactive oxygen species derived from NAD(P)H oxidase play a role on ethanol-induced hypertension and endothelial dysfunction in rat resistance arteries by Simplicio, Janaina A., do Vale, Gabriel T., Gonzaga, Natália A., Leite, Letícia N., Hipólito, Ulisses V., Pereira, Camila A., Tostes, Rita C., Tirapelli, Carlos R.

“…Chronic ethanol consumption is a risk factor for cardiovascular diseases. We studied whether NAD(P)H oxidase-derived reactive oxygen species (ROS) play a role…”
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Acute ethanol intake induces mitogen-activated protein kinase activation, platelet-derived growth factor receptor phosphorylation, and oxidative stress in resistance arteries by Gonzaga, Natália A., Callera, Glaucia E., Yogi, Alvaro, Mecawi, André S., Antunes-Rodrigues, José, Queiroz, Regina H., Touyz, Rhian M., Tirapelli, Carlos R.

“…In the present study, we investigated the role of angiotensin type I (AT 1 ) receptor in reactive oxygen species (ROS) generation and mitogen-activated protein…”
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Data on the mechanisms underlying succinate-induced aortic contraction by Gonzaga, Natália A., Simplicio, Janaina A., Leite, Letícia N., Vale, Gabriel T., Carballido, José M., Alves-Filho, José C., Tirapelli, Carlos R.

“…We describe the mechanisms underlying the vascular contraction induced by succinate. The data presented here are related to the article entitled…”
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Acute restraint stress increases blood pressure and oxidative stress in the cardiorenal system of rats: a role for AT 1 receptors by do Vale, Gabriel T, Leoni, Drieli, Sousa, Arthur H, Gonzaga, Natália A, Uliana, Daniela L, La Gata, Davi C, Resstel, Leonardo B, Padovan, Cláudia M, Tirapelli, Carlos R

“…We evaluate whether acute restraint stress may affect the oxidative state of the cardiorenal system and the possible contribution of angiotensin II/AT…”
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