Search Results - "González García, Jorge"
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Acidic Lysosome-Anchoring Croconium-Based Nanoplatform for Enhanced Triple-Mode Bioimaging and Fe3+-Triggered Tumor Synergistic Therapy
Published in ACS applied materials & interfaces (04-09-2024)“…Metal-modulated croconium dyes with multimodal-imaging and synergistic therapy in the tumor microenvironment have exhibited great potential in tumor…”
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Modulating the G‐Quadruplex and Duplex DNA Binding by Controlling the Charge of Fluorescent Molecules
Published in Chemistry : a European journal (27-01-2023)“…Two fluorescent and non‐toxic spirobifluorene molecules bearing either positive (Spiro‐NMe3) or negative (Spiro‐SO3) charged moieties attached to the same…”
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Earliest known human burial in Africa
Published in Nature (London) (06-05-2021)“…The origin and evolution of hominin mortuary practices are topics of intense interest and debate 1 – 3 . Human burials dated to the Middle Stone Age (MSA) are…”
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Development of Polyamine‐Substituted Triphenylamine Ligands with High Affinity and Selectivity for G‐Quadruplex DNA
Published in Chembiochem : a European journal of chemical biology (17-04-2020)“…Currently, significant efforts are devoted to designing small molecules able to bind selectively to guanine quadruplexes (G4s). These noncanonical DNA…”
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Aza‐Macrocyclic Triphenylamine Ligands for G‐Quadruplex Recognition
Published in Chemistry : a European journal (25-07-2018)“…A new series of triphenylamine‐based ligands with one (TPA1PY), two (TPA2PY) or three pendant aza‐macrocycle(s) (TPA3PY) has been synthesised and studied by…”
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Clinical potential of circulating free DNA and circulating tumour cells in patients with metastatic non‐small‐cell lung cancer treated with pembrolizumab
Published in Molecular oncology (01-11-2021)“…Immune checkpoint inhibitors, such as pembrolizumab, are revolutionizing therapeutic strategies for different cancer types, including non‐small‐cell lung…”
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Golden Guardians: Advanced pH Sensors with Built‐in Antimicrobial Defense
Published in Advanced optical materials (01-10-2024)“…Gold nanoclusters (Au NCs) capped with a small biomolecule, namely (+)‐norephedrine, (Au@Nore) display exceptional performance as fluorescent pH sensors. They…”
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Ditopic Aza-Scorpiand Ligands Interact Selectively with ds-RNA and Modulate the Interaction upon Formation of Zn2+ Complexes
Published in Molecules (Basel, Switzerland) (28-06-2021)“…Nucleic acids are essential biomolecules in living systems and represent one of the main targets of chemists, biophysics, biologists, and nanotechnologists…”
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Impact of the zinc complexation of polytopic polyaza ligands on the interaction with double and single stranded DNA/RNA and antimicrobial activity
Published in Dalton transactions : an international journal of inorganic chemistry (02-05-2023)“…Metal complexes have gained a huge interest in the biomedical research in the last decade because of the access to unexplored chemical space with regards to…”
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Identification of Aryl Polyamines Derivatives as Anti- Trypanosoma cruzi Agents Targeting Iron Superoxide Dismutase
Published in Pharmaceutics (31-12-2022)“…Chagas disease (CD) is a tropical and potentially fatal infection caused by . Although CD was limited to Latin America as a silent disease, CD has become…”
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Alkaloids as Photosensitisers for the Inactivation of Bacteria
Published in Antibiotics (Basel) (08-12-2021)“…Antimicrobial photodynamic therapy has emerged as a powerful approach to tackle microbial infections. Photodynamic therapy utilises a photosensitiser, light,…”
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Revealing interactions between polyaza pyridinophane compounds and DNA/RNA polynucleotides by SERS spectroscopy
Published in Journal of Raman spectroscopy (01-10-2014)“…Surface‐enhanced Raman scattering spectroscopy (SERS) in the near‐infrared region had been applied to study interactions of polyaza pyridinophanes with single…”
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Satisfacción de las necesidades psicológicas básicas de los estudiantes en función del modelo organizativo empleado en la asignatura de Actividades en el Medio Natural (Satisfaction of the basic psychological needs of the students according to the organisational model used in the subject of Activities in the Natural Environment): .
Published in Retos (Madrid) (17-09-2024)“…El objetivo de este estudio fue analizar la influencia del modelo organizativo utilizado para impartir la asignatura de Actividades en el Medio Natural sobre…”
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Evaluation of the lung immune prognostic index in advanced non-small cell lung cancer patients under nivolumab monotherapy
Published in Translational lung cancer research (01-12-2019)“…The lung immune prognostic index (LIPI) has been proposed as a new categorical blood-based biomarker to select advanced non-small cell lung cancer (NSCLC)…”
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Initial Biological Assessment of Upconversion Nanohybrids
Published in Biomedicines (09-10-2021)“…Nanoparticles for medical use should be non-cytotoxic and free of bacterial contamination. Upconversion nanoparticles (UCNPs) coated with cucurbit[7]uril…”
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PD-(L)1 Inhibitors in Combination with Chemotherapy as First-Line Treatment for Non-Small-Cell Lung Cancer: A Pairwise Meta-Analysis
Published in Journal of clinical medicine (03-07-2020)“…The combination of programmed cell death-1 (PD-1)/programmed death ligand-1 (PD-L1) inhibitors with chemotherapy has emerged as a promising therapeutic option…”
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Análisis del Impacto Social del Curso de Acceso a La Universidad (GAU) del Plan Integral Pueblo Gitano de La Generalitat de Catalunya
Published in International journal of Roma studies (15-07-2021)“…La situación social y educativa del Pueblo Gitano es claramente alarmante: únicamente un 1% ha conseguido finalizar estudios universitarios, mientras que casi…”
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Enhanced Parallel Sine Cosine Algorithm for Constrained and Unconstrained Optimization
Published in Mathematics (Basel) (01-04-2022)“…The sine cosine algorithm’s main idea is the sine and cosine-based vacillation outwards or towards the best solution. The first main contribution of this paper…”
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Evaluación educativa de los estudiantes en una red social en línea
Published in Revista iberoamericana de educación (01-01-2014)“…Los sistemas que guardan a lo largo del tiempo las interacciones entre los estudiantes y los profesores son una auténtica mina de oro que nos permite predecir…”
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Caracterización de pacientes con traumatismos torácicos atendidos en el servicio de Cirugía General. Cienfuegos, 2019-2020
Published in MediSur (01-10-2022)“…RESUMEN Fundamento el traumatismo torácico es un cuadro clínico complejo que puede comprometer la vida del paciente. Por ello es de interés su estudio y…”
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