Search Results - "González Arbeláez, Luisa F."
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Calcineurin/P38MAPK/HSP27-dependent pathways are involved in the attenuation of postischemic mitochondrial injury afforded by sodium bicarbonate co-transporter (NBCe1) inhibition
Published in Biochemical pharmacology (01-03-2019)“…[Display omitted] The electrogenic sodium bicarbonate co-transporter isoform 1 (NBCe1) plays an important role in ischemia-reperfusion injury. The…”
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Survival kinase-dependent pathways contribute to gender difference in the response to myocardial ischemia–reperfusion and ischemic post-conditioning
Published in Cardiovascular pathology (01-03-2018)“…The response to ischemia/reperfusion and the effects of ischemic post-conditioning (IPC) are sex-dependent, but the mechanisms have not been clarified. Male…”
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Antioxidant Activity and Cardioprotective Effect of a Nonalcoholic Extract of Vaccinium meridionale Swartz during Ischemia-Reperfusion in Rats
Published in Evidence-based complementary and alternative medicine (01-01-2013)“…Our objective was to assess the antioxidant properties and the effects against the reperfusion injury of a nonalcoholic extract obtained by fermentation from…”
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Benzolamide perpetuates acidic conditions during reperfusion and reduces myocardial ischemia-reperfusion injury
Published in Journal of applied physiology (1985) (01-08-2018)“…During ischemia, increased anaerobic glycolysis results in intracellular acidosis. Activation of alkalinizing transport mechanisms associated with carbonic…”
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Isoespintanol, a monoterpene isolated from oxandra cf xylopioides, ameliorates the myocardial ischemia-reperfusion injury by AKT/PKCε/eNOS-dependent pathways
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-04-2020)“…Purpose To determine the actions of isoespintanol (Isoesp) on post-ischemic myocardial and mitochondrial alterations. Methods Hearts removed from Wistar rats…”
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Is N-methylacetazolamide a possible new therapy against ischemia-reperfusion injury?
Published in Frontiers in pharmacology (10-08-2023)“…The increase of intracellular Ca 2+ concentration, produced principally by its influx through the L-type Ca 2+ channels, is one of the major contributors to…”
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Mitochondrial KATP channels participate in the limitation of infarct size by cariporide
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-06-2011)“…The objective of this study is to assess the participation of mitochondrial ATP-sensitive potassium (mitoK ATP ) channels in the cardioprotective effects of…”
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Myocardial and mitochondrial effects of the anhydrase carbonic inhibitor ethoxzolamide in ischemia‐reperfusion
Published in Physiological reports (01-11-2021)“…We have previously demonstrated that inhibition of extracellularly oriented carbonic anhydrase (CA) isoforms protects the myocardium against…”
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Ex Vivo Treatment with a Polyphenol-Enriched Cocoa Extract Ameliorates Myocardial Infarct and Postischemic Mitochondrial Injury in Normotensive and Hypertensive Rats
Published in Journal of agricultural and food chemistry (29-06-2016)“…Our objective was to determine the effects of a polyphenol-enriched cocoa extract (PCE) on myocardial postischemic alterations in normotensive (Wistar rats, W)…”
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Gsk-3β Inhibitors Mimic the Cardioprotection Mediated by Ischemic Pre- and Postconditioning in Hypertensive Rats
Published in BioMed research international (01-01-2013)“…The aim of this study was to examine the effects of GSK-3β inhibitors compared with PRE and POS in spontaneously hypertensive rats (SHR). Isolated hearts were…”
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Effect of an Ilex paraguariensis (yerba mate) extract on infarct size in isolated rat hearts: the mechanisms involved
Published in Food & function (01-02-2016)“…Tea made from Ilex paraguariensis (IP) dried and minced leaves is a beverage widely consumed by large populations in South America as a source of caffeine…”
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Hydrocortisone cardioprotection in ischaemia/reperfusion injury involves antioxidant mechanisms
Published in European journal of clinical investigation (01-05-2024)“…Background Glucocorticoid (GR) and mineralocorticoid (MR) receptors are highly expressed in cardiac tissue, and both can be activated by corticosteroids. MR…”
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Cardioprotective effects of N-methylacetazolamide mediated by inhibition of L-type Ca2+ channel current
Published in Biochimica et biophysica acta. General subjects (01-05-2022)“…Our objective was to examine the effects of N-methylacetazolamide (NMA), a non‑carbonic anhydrase inhibitor, on ischemia-reperfusion injury. Isolated rat…”
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Protective effects of N-(2-mercaptopropionyl)-glycine against ischemia–reperfusion injury in hypertrophied hearts
Published in Experimental and molecular pathology (01-02-2013)“…The beneficial effects of N-(2-mercaptopropionyl)-glycine (MPG) against ischemia–reperfusion injury in normotensive animals have been previously studied. Our…”
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Apelin/APJ signaling in IGF-1-induced acute mitochondrial and antioxidant effects in spontaneously hypertensive rat myocardium
Published in Journal of physiology and biochemistry (25-10-2024)“…IGF-1 and apelin are released in response to exercise training with beneficial effects. Previously we demonstrated that a swimming routine is effective to…”
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Cardioprotective efficacy against reperfusion injury of EMD-87580: Comparison to ischemic postconditioning
Published in European journal of pharmacology (15-08-2014)“…Previous results show that prolonged treatment with EMD-87580 (EMD) NHE-1 blocker attenuates and reverses postinfarction remodelling. Our aim was to evaluate…”
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Cardioprotection of benzolamide in a regional ischemia model: Role of eNOS/NO
Published in Experimental and molecular pathology (01-12-2018)“…Recent studies from our laboratory show the cardioprotective action of benzolamide (BZ, carbonic anhydrase inhibitor) against ischemia-reperfusion injury…”
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Acute treatment with copoazú fermented extract ameliorates myocardial ischemia-reperfusion injury via eNOS activation
Published in Journal of functional foods (01-07-2017)“…•Copoazú fermented extract (CFE) protects against ischemia-reperfusion injury.•Fermentation decreases the antioxidant power and increases the cardioprotective…”
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Cardioprotective effects of N-methylacetazolamide mediated by inhibition of L-type Ca 2+ channel current
Published in Biochimica et biophysica acta. General subjects (01-05-2022)“…Our objective was to examine the effects of N-methylacetazolamide (NMA), a non‑carbonic anhydrase inhibitor, on ischemia-reperfusion injury. Isolated rat…”
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Participation of mitochondrial permeability transition pore in the effects of ischemic preconditioning in hypertrophied hearts: Role of NO and mitoKATP
Published in International journal of cardiology (05-06-2013)“…Abstract Background The mitochondrial permeability transition pore (mPTP) plays an important role in ischemia–reperfusion in normotensive animals. Our study…”
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