Search Results - "González‐Romero, Rodrigo"
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Comparative structure of vertebrate sperm chromatin
Published in Journal of structural biology (01-11-2014)“…A consistent feature of sperm nuclei is its exceptionally compact state in comparison with somatic nuclei. Here, we have examined the structural organization…”
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Basic surface features of nuclear FKBPs facilitate chromatin binding
Published in Scientific reports (19-06-2017)“…The nucleoplasmin family of histone chaperones is identified by a pentamer-forming domain and multiple acidic tracts that mediate histone binding and chaperone…”
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The CHROMEVALOA database: a resource for the evaluation of Okadaic Acid contamination in the marine environment based on the chromatin-associated transcriptome of the mussel Mytilus galloprovincialis
Published in Marine drugs (12-03-2013)“…Okadaic Acid (OA) constitutes the main active principle in Diarrhetic Shellfish Poisoning (DSP) toxins produced during Harmful Algal Blooms (HABs),…”
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Unique yeast histone sequences influence octamer and nucleosome stability
Published in FEBS letters (01-08-2016)“…Yeast nucleosomes are known to be intrinsically less stable than those from higher eukaryotes. This difference presents significant challenges for the…”
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The evolutionary differentiation of two histone H2A.Z variants in chordates (H2A.Z-1 and H2A.Z-2) is mediated by a stepwise mutation process that affects three amino acid residues
Published in BMC evolutionary biology (04-02-2009)“…The histone H2A family encompasses the greatest number of core histone variants of which the replacement variant H2A.Z is currently one of the most heavily…”
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Histone H2A (H2A.X and H2A.Z) variants in molluscs: molecular characterization and potential implications for chromatin dynamics
Published in PloS one (11-01-2012)“…Histone variants are used by the cell to build specialized nucleosomes, replacing canonical histones and generating functionally specialized chromatin domains…”
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Detection of invasive and cryptic species in marine mussels (Bivalvia, Mytilidae): A chromosomal perspective
Published in Journal for nature conservation (01-09-2017)“…Marine mussels illustrate a stunning variability in shape and color. Such variability, added to the scarcity of reliable morphological characters for their…”
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Quickly evolving histones, nucleosome stability and chromatin folding: All about histone H2A.Bbd
Published in Gene (30-04-2008)“…Histone H2A.Bbd ( Barr body- deficient) is a novel histone variant which is largely excluded from the inactive X chromosome of mammals. Discovered only 6 years…”
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Early Evolution of Histone Genes: Prevalence of an 'Orphon' H1 Lineage in Protostomes and Birth-and-Death Process in the H2A Family
Published in Journal of molecular evolution (01-05-2008)“…The study of histone evolution has experienced a rebirth, for two main reasons: the identification of new essential histone variants responsible for regulating…”
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Effects of Florida Red Tides on histone variant expression and DNA methylation in the Eastern oyster Crassostrea virginica
Published in Aquatic toxicology (01-05-2017)“…Massive algal proliferations known as Harmful Algal Blooms (HABs) represent one of the most important threats to coastal areas. Among them, the so-called…”
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Evolution of high mobility group nucleosome-binding proteins and its implications for vertebrate chromatin specialization
Published in Molecular biology and evolution (01-01-2015)“…High mobility group (HMG)-N proteins are a family of small nonhistone proteins that bind to nucleosomes (N). Despite the amount of information available on…”
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dBigH1, a second histone H1 in Drosophila, and the consequences for histone fold nomenclature
Published in Epigenetics (01-06-2014)“…Recently, Pérez-Montero and colleagues (Developmental cell, 26: 578-590, 2013) described the occurrence of a new histone H1 variant (dBigH1) in Drosophila. The…”
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The characterization of macroH2A beyond vertebrates supports an ancestral origin and conserved role for histone variants in chromatin
Published in Epigenetics (02-06-2016)“…Histone variants play a critical role in chromatin structure and epigenetic regulation. These "deviant" proteins have been historically considered as the…”
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Molecular and Biochemical Methods Useful for the Epigenetic Characterization of Chromatin-Associated Proteins in Bivalve Molluscs
Published in Frontiers in physiology (08-08-2017)“…Bivalve molluscs constitute a ubiquitous taxonomic group playing key functions in virtually all ecosystems, and encompassing critical commercial relevance…”
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Characterization of mussel H2A.Z.2: a new H2A.Z variant preferentially expressed in germinal tissues from Mytilus
Published in Biochemistry and cell biology (01-10-2016)“…Histones are the fundamental constituents of the eukaryotic chromatin, facilitating the physical organization of DNA in chromosomes and participating in the…”
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Interaction of chromatin with a histone H1 containing swapped N- and C-terminal domains
Published in Bioscience reports (01-06-2015)“…Although the details of the structural involvement of histone H1 in the organization of the nucleosome are quite well understood, the sequential events…”
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Chromatin specialization in bivalve molluscs: A leap forward for the evaluation of Okadaic Acid genotoxicity in the marine environment
Published in Comparative biochemistry and physiology. Toxicology & pharmacology (01-03-2012)“…Marine biotoxins synthesized by Harmful Algal Blooms (HABs) represent one of the most important sources of contamination in marine environments as well as a…”
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Birth-and-death long-term evolution promotes histone H2B variant diversification in the male germinal cell line
Published in Molecular biology and evolution (01-08-2010)“…The rich diversity within each of the five histone families (H1, H2A, H2B, H3, and H4) can hardly be reconciled with the notion of homogenizing evolution. The…”
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Histone genes of the razor clam Solen marginatus unveil new aspects of linker histone evolution in protostomes
Published in Genome (01-07-2009)“…The association of DNA with histones results in a nucleoprotein complex called chromatin that consists of repetitive nucleosomal subunits. Nucleosomes are…”
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Histone H2A
Published in PloS one (11-01-2012)“…Histone variants are used by the cell to build specialized nucleosomes, replacing canonical histones and generating functionally specialized chromatin domains…”
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