Search Results - "González‐Candelas, Fernando"
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Recombination in viruses: mechanisms, methods of study, and evolutionary consequences
Published in Infection, genetics and evolution (01-03-2015)“…Recombination is a pervasive process generating diversity in most viruses. It joins variants that arise independently within the same molecule, creating new…”
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SARS‐CoV‐2 RNA load in nasopharyngeal specimens from outpatients with breakthrough COVID‐19 due to Omicron BA.1 and BA.2
Published in Journal of medical virology (01-12-2022)“…This retrospective observational study compared severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) RNA load in nasopharyngeal specimens (NPs) from…”
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Genetic determinants of host tropism in Klebsiella phages
Published in Cell reports (Cambridge) (28-02-2023)“…Bacteriophages play key roles in bacterial ecology and evolution and are potential antimicrobials. However, the determinants of phage-host specificity remain…”
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Assessing the potential association between SARS‐CoV‐2 RNA load in the respiratory tract and COVID‐19 mortality
Published in Journal of medical virology (01-04-2021)Get full text
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One is not enough: On the effects of reference genome for the mapping and subsequent analyses of short-reads
Published in PLoS computational biology (27-01-2021)“…Mapping of high-throughput sequencing (HTS) reads to a single arbitrary reference genome is a frequently used approach in microbial genomics. However, the…”
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Effect of Ribavirin on the Mutation Rate and Spectrum of Hepatitis C Virus In Vivo
Published in Journal of Virology (01-06-2009)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Isolation and Characterization of Two Klebsiella pneumoniae Phages Encoding Divergent Depolymerases
Published in International journal of molecular sciences (30-04-2020)“…The emergence of multidrug-resistant bacteria is a major global health concern. The search for new therapies has brought bacteriophages into the spotlight, and…”
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Whole Genome Sequencing Analysis of Intrapatient Microevolution in Mycobacterium tuberculosis: Potential Impact on the Inference of Tuberculosis Transmission
Published in The Journal of infectious diseases (01-01-2014)“…Background. It has been accepted that the infection by Mycobacterium tuberculosis (M. tuberculosis) can be more heterogeneous than considered. The emergence of…”
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Molecular characterization of Treponema pallidum subsp. pallidum in Switzerland and France with a new multilocus sequence typing scheme
Published in PloS one (30-07-2018)“…Syphilis is an important public health problem and an increasing incidence has been noted in recent years. Characterization of strain diversity through…”
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Comprehensive Screening for Naturally Occurring Hepatitis C Virus Resistance to Direct-Acting Antivirals in the NS3, NS5A, and NS5B Genes in Worldwide Isolates of Viral Genotypes 1 to 6
Published in Antimicrobial agents and chemotherapy (01-04-2016)“…There is no comprehensive study available on the natural hepatitis C virus (HCV) polymorphism in sites associated with resistance including all viral genotypes…”
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Enterovirus co-infections and onychomadesis after hand, foot, and mouth disease, Spain, 2008
Published in Emerging infectious diseases (01-12-2011)“…Hand, foot, and mouth disease (HFMD), a common disease caused by enteroviruses (EVs), usually affects children. Clustered and sporadic HFMD cases, followed by…”
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Listeria monocytogenes , a silent foodborne pathogen in Ecuador
Published in Frontiers in microbiology (21-12-2023)“…is a foodborne pathogen that can produce serious, even fatal, infections. Among other foods, it can be found in unpasteurized dairy and ready-to-eat products…”
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Genome-wide mutational biases fuel transcriptional diversity in the Mycobacterium tuberculosis complex
Published in Nature communications (05-09-2019)“…The Mycobacterium tuberculosis complex (MTBC) members display different host-specificities and virulence phenotypes. Here, we have performed a comprehensive…”
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Domain Organization and Evolution of Multifunctional Autoprocessing Repeats-in-Toxin (MARTX) Toxin in Vibrio vulnificus
Published in Applied and Environmental Microbiology (01-01-2011)“…The objective of this study was to analyze multifunctional autoprocessing repeats-in-toxin (MARTX) toxin domain organization within the aquatic species Vibrio…”
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Isolation of Four Lytic Phages Infecting Klebsiella pneumoniae K22 Clinical Isolates from Spain
Published in International journal of molecular sciences (09-01-2020)“…The emergence of multi-drug-resistant bacteria represents a major public-health threat. Phages constitute a promising alternative to chemical antibiotics due…”
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Incidence and molecular epidemiology of hepatitis C virus reinfection in prisons in Catalonia, Spain (Re-HCV study)
Published in Scientific reports (25-09-2023)“…Hepatitis C virus (HCV) reinfection may hamper HCV elimination in prisons. We aimed to (i) determine the reinfection rate in people treated for HCV in Catalan…”
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Genotypic and phenotypic characterisation of a nosocomial outbreak of Candida auris in Spain during 5 years
Published in Mycoses (01-08-2024)“…Objectives The investigation of Candida auris outbreaks is needed to provide insights into its population structure and transmission dynamics. We genotypically…”
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Inference of the Life Cycle of Environmental Phages from Genomic Signature Distances to Their Hosts
Published in Viruses (19-05-2023)“…The environmental impact of uncultured phages is shaped by their preferred life cycle (lytic or lysogenic). However, our ability to predict it is very limited…”
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The population genetics and evolutionary epidemiology of RNA viruses
Published in Nature reviews. Microbiology (01-04-2004)“…RNA viruses are ubiquitous intracellular parasites that are responsible for many emerging diseases, including AIDS and SARS. Here, we discuss the principal…”
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Molecular evolution in court: analysis of a large hepatitis C virus outbreak from an evolving source
Published in BMC biology (19-07-2013)“…Molecular phylogenetic analyses are used increasingly in the epidemiological investigation of outbreaks and transmission cases involving rapidly evolving RNA…”
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