Search Results - "González, Lázaro Gil"

Evaluation in Mice of the Immunogenicity of a Tetravalent Subunit Vaccine Candidate Against Dengue Virus Using Mucosal and Parenteral Immunization Routes by Lazo Vázquez, Laura, Gil González, Lázaro, Marcos López, Ernesto, Pérez Fuentes, Yusleidi, Cervetto de Armas, Lázaro, Brown Richards, Enma, Valdés Prado, Iris, Suzarte Portal, Edith, Cobas Acosta, Karem, Yaugel Novoa, Melyssa, Romero Fernández, Yaremis, Guillén Nieto, Gerardo, Hermida Cruz, Lisset

“…Our group has developed a subunit vaccine candidate against Dengue virus (DENV) based on two different viral regions, the domain III of the envelope protein…”
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Screening for immune response against Dengue virus in Vietnamese non‐human primates: implications for vaccine developers by Lazo Vázquez, Laura, Suzarte Portal, Edith, Castro Velazco, Jorge, Yen, Phuong, Dung, Le Trung, Gil González, Lázaro, Valdés Prado, Iris, Marcos López, Ernesto, Cobas Acosta, Karem, Hien, Nguyen Dang, Guillén Nieto, Gerardo, Hermida Cruz, Lisset

“…One of the major problems faced for the development of a vaccine against Dengue virus is the lack of a suitable animal model. Although non‐human primates do…”
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Comparative proteomic analysis of growth hormone secretagogue A233 treatment of murine macrophage cells J774A.2 indicates it has a role in antiviral innate response by Martínez, Rebeca, de Villavicencio-Díaz, Teresa Núñez, Sánchez, Aniel, Ramos, Yassel, Ferro, Jesús Noda, González, Lázaro Gil, Méndez, Milagros, Rodríguez, Elsa, Marcos, Ernesto, Sánchez, Belinda, Masforrol, Yordanka, Garay, Hilda, Albericio, Fernando, Hermida, Lisset, González, Luis Javier, Vonasek, Eva, Estrada, Mario P, Besada, Vladimir

“…Growth hormone secretagogues (GHS), among other factors, regulate the release of GH. The biological activity of the secretagogue peptide A233 as a promoter of…”
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THP-1 cells transduced with CD16A utilize Fcγ receptor I and III in the phagocytosis of IgG-sensitized human erythrocytes and platelets by Gil Gonzalez, Lazaro, Fernandez-Marrero, Yuniel, Norris, Peter Alan Albert, Tawhidi, Zoya, Shan, Yuexin, Cruz-Leal, Yoelys, Won, Kevin Doyoon, Frias-Boligan, Kayluz, Branch, Donald R, Lazarus, Alan H

“…Fc gamma receptors (FcγRs) are critical effector receptors for immunoglobulin G (IgG) antibodies. On macrophages, FcγRs mediate multiple effector functions,…”
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Bispecific immune cell engager enhances the anticancer activity of CD16+ NK cells and macrophages in vitro, and eliminates cancer metastasis in NK humanized NOG mice by Khoshtinat Nikkhoi, Shahryar, Yang, Ge, Owji, Hajar, Grizotte-Lake, Mayara, Cohen, Rick I, Gil Gonzalez, Lazaro, Massumi, Mohammad, Hatefi, Arash

“…BackgroundIn a prior report, we detailed the isolation and engineering of a bispecific killer cell engager, referred to as BiKE:E5C1. The BiKE:E5C1 exhibits…”
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Antagonism of the Platelet-Activating Factor Pathway Mitigates Inflammatory Adverse Events Driven by Anti-erythrocyte Antibody Therapy in Mice by Won, Kevin Doyoon, Gil Gonzalez, Lazaro, Cruz-Leal, Yoelys, Pavon Oro, Alequis, Lazarus, Alan H

“…Immune thrombocytopenia (ITP) is an autoimmune disease characterized by low platelet counts primarily due to antiplatelet autoantibodies. Anti-D is a…”
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Trogocytosis drives red blood cell antigen loss in association with antibody-mediated immune suppression by Cruz-Leal, Yoelys, Norris, Peter A. A., Gil Gonzalez, Lazaro, Marjoram, Danielle, Wabnitz, Hanna, Shan, Yuexin, Lazarus, Alan H.

“…•AMIS-inducing antibodies trigger in vivo RBC antigen and membrane loss independent of clearance.•AMIS-inducing antibodies, including anti-D, trigger in vitro…”
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Recombinant nucleocapsid-like particles from dengue-2 virus induce protective CD4+ and CD8+ cells against viral encephalitis in mice by Gil, Lázaro, López, Carlos, Lazo, Laura, Valdés, Iris, Marcos, Ernesto, Alonso, Ruby, Gambe, Ailyn, Martín, Jorge, Romero, Yaremis, Guzmán, María G., Guillén, Gerardo, Hermida, Lisset

“…Virus-like particles are a highly effective type of subunit vaccine that mimics the overall structure of virus particles without containing infectious genetic…”
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Serum from half of patients with immune thrombocytopenia triggers macrophage phagocytosis of platelets by Norris, Peter A. A., Tawhidi, Zoya, Sachs, Ulrich J., Cserti-Gazdewich, Christine M., Lin, Yulia, Callum, Jeannie, Gil Gonzalez, Lazaro, Shan, Yuexin, Branch, Donald R., Lazarus, Alan H.

“…•Incubation of ITP serum with normal donor platelets triggered platelet uptake via macrophage phagocytosis for sera from half of the patients with…”
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Serum from half of patients with immune thrombocytopenia trigger macrophage phagocytosis of platelets by Norris, Peter A A, Tawhidi, Zoya, Sachs, Ulrich J, Cserti-Gazdewich, Christine M, Lin, Yulia, Callum, Jeannie, Gil Gonzalez, Lazaro, Shan, Yuexin, Branch, Donald R, Lazarus, Alan H

“…Humoral antiplatelet factors, such as autoantibodies, are thought to primarily clear platelets by triggering macrophage phagocytosis in immune thrombocytopenia…”
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Human Fc gamma receptor IIIA blockade inhibits platelet destruction in a humanized murine model of ITP by Gil Gonzalez, Lazaro, Won, Kevin D., Tawhidi, Zoya, Cummins, Emma, Cruz-Leal, Yoelys, Tundidor Cabado, Yaima, Sachs, Ulrich J., Norris, Peter A. A., Shan, Yuexin, Bhakta, Varsha, Li, Janessa, Samudio, Ismael, Silva-Moreno, Begonia, Cerna-Portillo, Liza, Pavon Oro, Alequis, Bergqvist, Peter, Chan, Patrick, Moorehead, Amy, Sholzberg, Michelle, Sheffield, William P., Lazarus, Alan H.

“…•Human FcγRIII monovalent blocking as a 1-armed antibody or albumin fusion protein are effective in a humanized model of ITP.•The monovalent albumin fusion…”
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Elucidating the FC Receptor and Platelet Activation Factor -Driven Inflammatory Consequences of AntiRBC Antibody Therapy in 8 by Won, Kevin Doyoon, Gonzalez, Lazaro Gil, Lazarus, Alan

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Elucidating the FC Receptor and Platelet Activation Factor -Driven Inflammatory Consequences of AntiRBC Antibody Therapy in 8 by Won, Kevin Doyoon, Gonzalez, Lazaro Gil, Lazarus, Alan

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THP-1 cells transduced with CD16A utilize Fc[gamma] receptor I and III in the phagocytosis of IgG-sensitized human erythrocytes and platelets by Gil Gonzalez, Lazaro, Fernandez-Marrero, Yuniel, Norris, Peter Alan Albert, Tawhidi, Zoya, Shan, Yuexin, Cruz-Leal, Yoelys, Won, Kevin Doyoon, Frias-Boligan, Kayluz, Branch, Donald R, Lazarus, Alan H

“…Fc gamma receptors (Fc[gamma]Rs) are critical effector receptors for immunoglobulin G (IgG) antibodies. On macrophages, Fc[gamma]Rs mediate multiple effector…”
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Selective Monovalent Blockade of Human Fc [Gamma] Riii in a Humanized-Murine ITP Model: A New Frontier in Autoimmune Therapeutic Strategies? by Gonzalez, Lazaro Gil, Won, Kevin Doyoon, Tawhidi, Zoya, Cummins, Emma, Shan, Yuexin, Norris, Peter, Sachs, Ulrich, Bhakta, Varsha, Cruz-Leal, Yoelys, Shefield, William, Lazarus, Alan

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Selective Monovalent Blockade of Human Fc [Gamma] Riii in a Humanized-Murine ITP Model: A New Frontier in Autoimmune Therapeutic Strategies? by Gonzalez, Lazaro Gil, Won, Kevin Doyoon, Tawhidi, Zoya, Cummins, Emma, Shan, Yuexin, Norris, Peter, Sachs, Ulrich, Bhakta, Varsha, Cruz-Leal, Yoelys, Shefield, William, Lazarus, Alan

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