Search Results - "González, Florencia B"

Immune-neuroendocrine and metabolic disorders in human and experimental T. cruzi infection: New clues for understanding Chagas disease pathology by González, Florencia B., Villar, Silvina R., Pacini, M. Florencia, Bottasso, Oscar A., Pérez, Ana R.

“…Studies in mice undergoing acute Trypanosoma cruzi infection and patients with Chagas disease, led to identify several immune-neuroendocrine disturbances and…”
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Intranasal trans-sialidase-based vaccine against Trypanosoma cruzi triggers a mixed cytokine profile in the nasopharynx-associated lymphoid tissue and confers local and systemic immunogenicity by Pacini, María F., Balbi, Camila Bulfoni, Dinatale, Brenda, González, Florencia B., Prochetto, Estefania, De Hernández, María A., Cribb, Pamela, Farré, Cecilia, Espariz, Martín, Blancato, Víctor S., Magni, Christian, Marcipar, Iván, Pérez, Ana R.

“…Trypanosoma cruzi, the agent of Chagas disease, can infect through conjunctive or oral mucosas. Therefore, the induction of mucosal immunity by vaccination is…”
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Immune response triggered by Trypanosoma cruzi infection strikes adipose tissue homeostasis altering lipid storage, enzyme profile and adipokine expression by González, Florencia B., Villar, Silvina R., Toneatto, Judith, Pacini, María F., Márquez, Julia, D’Attilio, Luciano, Bottasso, Oscar A., Piwien-Pilipuk, Graciela, Pérez, Ana R.

“…Adipose tissue is a target of Trypanosoma cruzi infection being a parasite reservoir during the chronic phase in mice and humans. Previously, we reported that…”
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Immunoendocrine dysbalance during uncontrolled T. cruzi infection is associated with the acquisition of a Th-1-like phenotype by Foxp3+ T cells by González, Florencia B, Villar, Silvina R, Fernández Bussy, Rodrigo, Martin, Gaëlle H, Pérol, Louis, Manarin, Romina, Spinelli, Silvana V, Pilon, Caroline, Cohen, José Laurent, Bottasso, Oscar A, Piaggio, Eliane, Pérez, Ana R

“…Highlights • Treg/Teff cell balance is under endocrine control during T. cruzi infection. • During acute infection Treg cells acquire a pathogenic Th-1 like…”
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Genetic Engineering of Lactococcus lactis Co-producing Antigen and the Mucosal Adjuvant 3' 5'- cyclic di Adenosine Monophosphate (c-di-AMP) as a Design Strategy to Develop a Mucosal Vaccine Prototype by Quintana, Ingrid, Espariz, Martín, Villar, Silvina R, González, Florencia B, Pacini, Maria F, Cabrera, Gabriel, Bontempi, Iván, Prochetto, Estefanía, Stülke, Jörg, Perez, Ana R, Marcipar, Iván, Blancato, Victor, Magni, Christian

“…is a promising candidate for the development of mucosal vaccines. More than 20 years of experimental research supports this immunization approach. In addition,…”
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Death of adrenocortical cells during murine acute T. cruzi infection is not associated with TNF-R1 signaling but mostly with the type II pathway of Fas-mediated apoptosis by Pérez, Ana R., Lambertucci, Flavia, González, Florencia B., Roggero, Eduardo A., Bottasso, Oscar A., de Meis, Juliana, Ronco, Maria T., Villar, Silvina R.

“…•Adrenal apoptosis is likely mediated by the FasL/Fas pathway in T. cruzi-infection.•T cruzi-Infection is related with an exacerbated production of…”
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Evidence in Favor of an Alternative Glucocorticoid Synthesis Pathway During Acute Experimental Chagas Disease by da Silva Oliveira Barbosa, Esdras, Roggero, Eduardo A, González, Florencia B, Fernández, Rocío Del Valle, Carvalho, Vinicius Frias, Bottasso, Oscar A, Pérez, Ana R, Villar, Silvina R

“…It is well-established that infectious stress activates the hypothalamus-pituitary-adrenal axis leading to the production of pituitary adrenocorticotropin…”
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Evasion and Immuno-Endocrine Regulation in Parasite Infection: Two Sides of the Same Coin in Chagas Disease? by Morrot, Alexandre, Villar, Silvina R, González, Florencia B, Pérez, Ana R

“…Chagas disease is a serious illness caused by the protozoan parasite Trypanosoma cruzi. Nearly 30% of chronically infected people develop cardiac, digestive,…”
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Activation of PPARγ reduces N-acetyl-cysteine -induced hypercorticoidism by down-regulating MC2R expression into adrenal glands by Ventura, Raíssa D., Chaves, Amanda S., Magalhães, Nathalia S., Gonzalez, Florencia B., Pacini, Maria Florencia, Pérez, Ana Rosa, Silva, Patrícia M.R., Martins, Marco A., Carvalho, Vinicius F.

“…We previously demonstrated that oral supplementation with antioxidants induced hyperactivity of hypothalamus-pituitary-adrenal (HPA) axis, attested by…”
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