The continued need for animals to advance brain research

Policymakers aim to move toward animal-free alternatives for scientific research and have introduced very strict regulations for animal research. We argue that, for neuroscience research, until viable and translational alternatives become available and the value of these alternatives has been proven...

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Published in:Neuron (Cambridge, Mass.) Vol. 109; no. 15; pp. 2374 - 2379
Main Authors: Homberg, Judith R, Adan, Roger A H, Alenina, Natalia, Asiminas, Antonis, Bader, Michael, Beckers, Tom, Begg, Denovan P, Blokland, Arjan, Burger, Marilise E, van Dijk, Gertjan, Eisel, Ulrich L M, Elgersma, Ype, Englitz, Bernhard, Fernandez-Ruiz, Antonio, Fitzsimons, Carlos P, van Dam, Anne-Marie, Gass, Peter, Grandjean, Joanes, Havekes, Robbert, Henckens, Marloes J A G, Herden, Christiane, Hut, Roelof A, Jarrett, Wendy, Jeffrey, Kate, Jezova, Daniela, Kalsbeek, Andries, Kamermans, Maarten, Kas, Martien J, Kasri, Nael Nadif, Kiliaan, Amanda J, Kolk, Sharon M, Korosi, Aniko, Korte, S Mechiel, Kozicz, Tamas, Kushner, Steven A, Leech, Kirk, Lesch, Klaus-Peter, Lesscher, Heidi, Lucassen, Paul J, Luthi, Anita, Ma, Liya, Mallien, Anne S, Meerlo, Peter, Mejias, Jorge F, Meye, Frank J, Mitchell, Anna S, Mul, Joram D, Olcese, Umberto, González, Azahara Oliva, Olivier, Jocelien D A, Pasqualetti, Massimo, Pennartz, Cyriel M A, Popik, Piotr, Prickaerts, Jos, de la Prida, Liset M, Ribeiro, Sidarta, Roozendaal, Benno, Rossato, Janine I, Salari, Ali-Akbar, Schoemaker, Regien G, Smit, August B, Vanderschuren, Louk J M J, Takeuchi, Tomonori, van der Veen, Rixt, Smidt, Marten P, Vyazovskiy, Vladyslav V, Wiesmann, Maximilian, Wierenga, Corette J, Williams, Bella, Willuhn, Ingo, Wöhr, Markus, Wolvekamp, Monique, van der Zee, Eddy A, Genzel, Lisa
Format: Journal Article
Language:English
Published: United States Elsevier Limited 04-08-2021
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Summary:Policymakers aim to move toward animal-free alternatives for scientific research and have introduced very strict regulations for animal research. We argue that, for neuroscience research, until viable and translational alternatives become available and the value of these alternatives has been proven, the use of animals should not be compromised.
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ISSN:0896-6273
1097-4199
DOI:10.1016/j.neuron.2021.07.015