Search Results - "González, Addys"
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Potent immunomodulatory and antitumor effect of anti-CD20-IL2no-alpha tri-functional immunocytokine for cancer therapy
Published in Frontiers in immunology (09-12-2022)“…The anti-CD20 antibody rituximab (RTX) has substantially improved outcomes of patients with B-cell lymphomas, although more efficient therapies are needed for…”
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Frequent co-expression of EGFR and NeuGcGM3 ganglioside in cancer: it’s potential therapeutic implications
Published in Clinical & experimental metastasis (01-10-2016)“…Interaction between epidermal growth factor receptor (EGFR) signaling with GM3 ganglioside expression has been previously described. However, little is known…”
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Blocking EGFR with nimotuzumab: a novel strategy for COVID-19 treatment
Published in Immunotherapy (01-05-2022)“…Lung injury and STAT1 deficit induce EGFR overexpression in SARS-CoV-2 infection. A phase I/II trial was done to evaluate the safety and preliminary effect of…”
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Hydroxyapatite Nanoparticles as a Potential Long-Term Treatment of Cancer of Epithelial Origin
Published in ACS applied nano materials (27-05-2022)“…Among the various forms of cancer, non-small cell lung cancer is the most frequently diagnosed and the leading cause of deaths. CIMAvax-EGF has been introduced…”
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A cytotoxic humanized anti-ganglioside antibody produced in a murine cell line defective of N -glycolylated-glycoconjugates
Published in Immunobiology (1979) (01-12-2011)“…Abstract Gangliosides containing the N -glycolyl (NGc) form of sialic acid are tumor-associated antigens and promising candidates for cancer therapy. We…”
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Reposicionamiento del anticuerpo monoclonal humanizado cubano nimotuzumab en el tratamiento de pacientes con COVID-19
Published in Anales de la Academia de Ciencias de Cuba (01-08-2023)“…RESUMEN Introducción: La lesión pulmonar y el déficit del transductor de señal y el activador de la transcripción 1 (STAT1) inducen la sobreexpresión de…”
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Phase I single-dose study of intracavitary-administered Nimotuzumab labeled with 188-Re in adult recurrent high-grade glioma
Published in Cancer biology & therapy (01-03-2008)“…Radioimmunotherapy (RIT) may improve the management of malignant gliomas. A Phase I clinical trial was performed to evaluate, for the first time, the toxicity…”
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Synergistic potentiation of the anti-metastatic effect of anti EGFR mAb by its combination with immunotherapies targeting the ganglioside NGcGM3
Published in Oncotarget (08-05-2018)“…Several Anti-EGFR mAbs are register for the treatment of human cancer. However, their impact on patients overall survival has been limited by tumor resistance…”
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The chicken animal model for ovarian cancer and for pharmacological and toxicological evaluation of NGcGM3 ganglioside based treatments
Published in Toxicology letters (20-10-2017)Get full text
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ANTI-INFLAMMATORY ACTIVITY OF PHYCOCYANIN EXTRACT IN ACETIC ACID-INDUCED COLITIS IN RATS
Published in Pharmacological research (01-01-1999)“…The anti-inflammatory effect of c -phycocyanin extract was studied in acetic acid-induced colitis in rats. Phycocyanin (150, 200 and 300 mg kg−1p.o.) was…”
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Effect of phycocyanin in zymosan-induced arthritis in mice-phycocyanin as an antiarthritic compound
Published in Drug development research (01-10-1999)“…The antiinflammatory effect of a phycocyanin extract was studied in zymosan‐induced arthritis model in mice. Four days after the intraarticular injection of…”
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Efectos antipsoriásico, antiinflamatorio y analgésico del propoleo rojo colectado en Cuba
Published in Revista cubana de farmacía (01-04-1996)“…Se evaluaron los efectos antipsoriásico, antiinflamatorio y analgésico de un extracto de propóleo rojo. Este extracto induce la formación de la capa granular…”
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13
Antipsoriatic, anti-inflammatory, and analgesic effects of an extract of red propolis
Published in Zhōngguó yàolĭ xuébào (01-05-1997)“…To study the antipsoriatic, anti-inflammatory, and analgesic effects of ethanolic extract of red propolis. This extract induced the formation of granular layer…”
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