Treatment‐induced neuropathy of diabetes: an update

Background and aims: Treatment‐induced neuropathy of diabetes is an acute small‐fibre neuropathy associated with rapid glycaemia improvement. Methods: This study is a narrative review carried out based on a bibliographic review, using articles indexed in PubMed/Medline and Scielo. Results: This enti...

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Published in:	Practical diabetes (2011) Vol. 40; no. 6; pp. 28 - 35
Main Authors:	Quiroz‐Aldave, Juan Eduardo, Concepción‐Zavaleta, Marcio José, Carmen Durand‐Vásquez, María, Gamarra‐Osorio, Elman Rolando, Alcalá‐Mendoza, Rosa María, Puelles‐León, Susan Luciana, Ildefonso‐Najarro, Sofía, Concepción‐Urteaga, Luis Alberto, Gonzáles‐Mendoza, Jorge Estanislao, Paz‐Ibarra, José
Format:	Journal Article
Language:	English
Published:	Chichester, UK John Wiley & Sons, Ltd 01-11-2023 Wiley Subscription Services, Inc
Subjects:	Diabetes diabetes mellitus diabetic neuropathies Diabetic neuropathy Medical treatment Pathophysiology Side effects small fibre neuropathy treatment
Online Access:	Get full text
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Summary:	Background and aims: Treatment‐induced neuropathy of diabetes is an acute small‐fibre neuropathy associated with rapid glycaemia improvement. Methods: This study is a narrative review carried out based on a bibliographic review, using articles indexed in PubMed/Medline and Scielo. Results: This entity is more frequent in adult patients with poor previous glycaemic control. Its precise pathophysiology is unknown, but it is likely related to unrestored microcirculation changes that occurred during the hyperglycaemic period. It presents with intense, sudden neuropathic pain and autonomic dysfunction after a rapid glycaemic correction and a poorer analgesic response than in diabetic neuropathy. Conclusions: Since rapid glycaemia correction is the cause of this problem, clinical practice guidelines that can help physicians to prevent, diagnose and manage this entity should be developed. Copyright © 2023 John Wiley & Sons.
ISSN:	2047-2897 2047-2900
DOI:	10.1002/pdi.2485