Search Results - "Gontrum, Eva Q."

Moderating role of physical activity on hippocampal iron deposition and memory outcomes in typically aging older adults by Lee, Shannon Y., Paolillo, Emily W., Saloner, Rowan, Cobigo, Yann, Diaz, Valentina E., Gontrum, Eva Q., VandeBunte, Anna, Chatterjee, Ankita, Tucker, Miwa, Kramer, Joel H., Casaletto, Kaitlin B.

“…Physical activity (PA) is linked to better cognitive and brain health, though its mechanisms are unknown. While brain iron is essential for normal function,…”
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Unveiling the proteome-wide autoreactome enables enhanced evaluation of emerging CAR T cell therapies in autoimmunity by Bodansky, Aaron, Yu, David J.L, Rallistan, Alysa, Kalaycioglu, Muge, Boonyaratanakornki, Jim, Green, Damian J, Gauthier, Jordan, Turtle, Cameron J, Zorn, Kelsey, O'Donovan, Brian, Mandel-Brehm, Caleigh, Asaki, James, Kortbawi, Hannah, Kung, Andrew F, Rackaityte, Elze, Wang, Chung-Yu, Saxena, Aditi, de Dios, Kimberly, Masi, Gianvito, Nowak, Richard J, O'Connor, Kevin C, Li, Hao, Diaz, Valentina E, Saloner, Rowan, Casaletto, Kaitlin B, Gontrum, Eva Q, Chan, Brandon, Kramer, Joel H, Wilson, Michael R, Utz, Paul J, Hill, Joshua A, Jackson, Shaun W, Anderson, Mark S, DeRisi, Joseph L

“…Given the global surge in autoimmune diseases, it is critical to evaluate emerging therapeutic interventions. Despite numerous new targeted immunomodulatory…”
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Neuropsychiatric Profiles and Cerebral Amyloid Burden in Adults without Dementia by Gontrum, Eva Q, Paolillo, Emily W, Lee, Shannon, Diaz, Valentina, Ehrenberg, Alexander, Saloner, Rowan, Mundada, Nidhi S, La Joie, Renaud, Rabinovici, Gil, Kramer, Joel H, Casaletto, Kaitlin B

“…We comprehensively evaluated how self- and informant-reported neuropsychiatric symptoms (NPS) were differentially associated with cerebral amyloid-beta (Aβ)…”
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Sex‐specific effects of SNAP‐25 genotype on verbal memory and Alzheimer's disease biomarkers in clinically normal older adults by Saloner, Rowan, Paolillo, Emily W., Wojta, Kevin J., Fonseca, Corrina, Gontrum, Eva Q., Lario‐Lago, Argentina, Rabinovici, Gil D., Yokoyama, Jennifer S., Rexach, Jessica E., Kramer, Joel H., Casaletto, Kaitlin B.

“…Introduction We tested sex‐dependent associations of variation in the SNAP‐25 gene, which encodes a presynaptic protein involved in hippocampal plasticity and…”
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Plasma phosphorylated tau‐217 exhibits sex‐specific prognostication of cognitive decline and brain atrophy in cognitively unimpaired adults by Saloner, Rowan, VandeVrede, Lawren, Asken, Breton M., Paolillo, Emily W., Gontrum, Eva Q., Wolf, Amy, Lario‐Lago, Argentina, Milà‐Alomà, Marta, Triana‐Baltzer, Gallen, Kolb, Hartmuth C., Dubal, Dena B., Rabinovici, Gil D., Miller, Bruce L., Boxer, Adam L., Casaletto, Kaitlin B., Kramer, Joel H.

“…INTRODUCTION Accumulating evidence indicates disproportionate tau burden and tau‐related clinical progression in females. However, sex differences in plasma…”
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Plasma phosphorylated‐tau181 is an indicator of early manifestations of neuropsychiatric symptoms in younger subclinical individuals by Gontrum, Eva Q., Saloner, Rowan, Chan, Brandon, Lago, Argentina Lario, Rojas, Julio C., Casaletto, Kaitlin B, Kramer, Joel H.

“…Background Neuropsychiatric symptoms (NPS) can be the first manifestations of Alzheimer’s disease (AD), predict faster disease progression, and are more…”
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Sex differences in plasma phosphorylated‐tau181 vary between older adults with and without mild cognitive impairment by Tucker, Miwa, Kramer, Joel H., Casaletto, Kaitlin B., Gontrum, Eva Q., Lago, Argentina Lario, Rojas, Julio C., Saloner, Rowan, Chan, Brandon

“…Background Women exhibit higher tau pathology than men on central nervous system biomarkers of tau (e.g., PET imaging, CSF), particularly among APOE4 carriers…”
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Plasma glial fibrillary acidic protein as a moderator along the Alzheimer’s disease biomarker cascade by Saloner, Rowan, Asken, Breton M., Gontrum, Eva Q., Chan, Brandon, Lago, Argentina Lario, Rojas, Julio C., Miller, Bruce L., Rabinovici, Gil D., Casaletto, Kaitlin B, Kramer, Joel H.

“…Background Astrocyte reactivity may contribute to pathogenic relationships between β‐amyloid (A), phosphorylated tau (T), neurodegeneration (N), and cognition…”
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APOE Genotype Moderates the Relationship Between Plasma Phosphorylated‐tau181 and Pattern Separation Performance in Non‐demented Adults by Diaz, Valentina E, Memel, Molly B, Gaynor, Leslie S, Gontrum, Eva Q., Chan, Brandon, Lago, Argentina Lario, Yassa, Michael A., Rojas, Julio C., Casaletto, Kaitlin B, Kramer, Joel H., Saloner, Rowan

“…Background The apolioprotein e (APOE) e4 allele enhances risk for Alzheimer’s disease (AD), particularly an amnestic AD phenotype with medial temporal lobe tau…”
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Unveiling the proteome-wide autoreactome enables enhanced evaluation of emerging CAR-T therapies in autoimmunity by Bodansky, Aaron, Yu, David Jl, Rallistan, Alysa N, Kalaycioglu, Muge, Boonyaratanakornkit, Jim, Green, Damian J, Gauthier, Jordan, Turtle, Cameron J, Zorn, Kelsey C, O'Donovan, Brian, Mandel-Brehm, Caleigh, Asaki, James, Kortbawi, Hannah, Kung, Andrew F, Rackaityte, Elze, Wang, Chung-Yu, Saxena, Aditi, de Dios, Kimberly, Masi, Gianvito, Nowak, Richard J, O'Connor, Kevin C, Li, Hao, Diaz, Valentina E, Saloner, Rowan, Casaletto, Kaitlin B, Gontrum, Eva Q, Chan, Brandon J, Kramer, Joel H, Wilson, Michael R, Utz, Paul J, Hill, Joshua A, Jackson, Shaun W, Anderson, Mark S, DeRisi, Joseph L

“…Given the global surge in autoimmune diseases, it is critical to evaluate emerging therapeutic interventions. Despite numerous new targeted immunomodulatory…”
Get full text