Search Results - "Gong, Xiuli"

Correction of RNA splicing defect in β654-thalassemia mice using CRISPR/Cas9 gene-editing technology by Lu, Dan, Gong, Xiuli, Fang, Yudan, Guo, Xinbing, Chen, Yanwen, Yang, Fan, Zhao, Guijun, Ma, Qingwen, Zeng, Yitao, Zeng, Fanyi

“…β654-thalassemia is a prominent Chinese subtype of b-thalassemia, representing 17% of all cases of β-thalassemia in China. The molecular mechanism underlying…”
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Production of biologically active human factor IX-Fc fusion protein in the milk of transgenic mice by Yan, Hong, Gong, Xiuli, Xu, Miao, Guo, Xinbing, Chen, Yanwen, Xue, Yan, Zeng, Yitao, Zeng, Fanyi

“…Objective To investigate the feasibility of producing human IgG1 Fc fragment fused factor IX (FIX-Fc) in the milk of transgenic animals, for an alternative…”
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The Mesenchymal Stem Cells Derived from Transgenic Mice Carrying Human Coagulation Factor VIII Can Correct Phenotype in Hemophilia A Mice by Wang, Qing, Gong, Xiuli, Gong, Zhijuan, Ren, Xiaoyie, Ren, Zhaorui, Huang, Shuzhen, Zeng, Yitao

“…Hemophilia A （HA） is an inherited X-linked recessive bleeding disorder caused by coagulant factor VIII （FVIII） deficiency. Previous studies showed that…”
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Bovine prolactin promotes the expression of human transferrin in the milk of transgenic mice by Li, Song, Guo, Xinbing, Gong, Xiuli, Xu, Miao, Yan, Jingbin, Huang, Ying, Ren, Zhaorui

“…The bovine prolactin vector was injected directly into the mammary glands of mice carrying the human transferrin transgene to investigate its effect on the…”
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A novel transgenic mouse model produced from lentiviral germline integration for the study of β-thalassemia gene therapy by Li, Wei, Xie, Shuyang, Guo, Xinbing, Gong, Xiuli, Wang, Shu, Lin, Dan, Zhang, Jingzhi, Ren, Zhaorui, Huang, Shuzhen, Zeng, Fanyi, Zeng, Yitao

“…beta-thalassemia is one of the most common genetic diseases in the world and requires extensive therapy. Lentiviral-mediated gene therapy has been successfully…”
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A mediator of phosphorylated Smad2/3, evodiamine, in the reversion of TAF-induced EMT in normal colonic epithelial cells by Yang, Wanbin, Gong, Xiuli, Wang, Xiulian, Huang, Chao

“…Summary Purpose Transdifferentiation exists within stromal cells in the tumour microenvironment. Transforming growth factor-β (TGF-β) secreted by…”
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Therapeutic effects of hematopoietic stem cell derived from gene-edited mice on β654-thalassemia by Lu, Dan, Gong, Xiuli, Guo, Xinbing, Chen, Yanwen, Zhu, Yiwen, Fang, Yudan, Cai, Qin, Xu, Miao, Yang, Hua, Li, Dali, Zeng, Yitao, Zeng, Fanyi

“…β-thalassemia is an inherited blood disease caused by reduced or inadequate β-globin synthesis due to β-globin gene mutation. Our previous study developed a…”
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The Hematopoietic Reconstitution through Intra-Bone-Marrow Injection Using Murine Fetal Liver Hematopoietic Stem Cells by Yang, Guanheng, Yi, Qingfu, Chi, Yanan, Zhang, Shaoqing, Gong, Xiuli, Ji, Ma, Fanyi, Zeng

“…Hematopoietic stem cells (HSCs) were considered an effective treatment option for many blood diseases and autoimmune diseases. HSCs can currently be isolated…”
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Maternal Prkce expression in mature oocytes is critical for the first cleavage facilitating maternal‐to‐zygotic transition in mouse early embryos by Zhang, Shaoqing, Gong, Xiuli, Zhou, Yiye, Ma, Qingwen, Cai, Qin, Yang, Guanheng, Guo, Xinbing, Chen, Yanwen, Xu, Miao, Zhu, Yiwen, Zeng, Yitao, Zeng, Fanyi

“…Objectives Early embryo development is dependent on the regulation of maternal messages stored in the oocytes during the maternal‐to‐zygote transition…”
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Scaling up the national methadone maintenance treatment program in China: achievements and challenges by Yin, Wenyuan, Hao, Yang, Sun, Xinhua, Gong, Xiuli, Li, Fang, Li, Jianhua, Rou, Keming, Sullivan, Sheena G, Wang, Changhe, Cao, Xiaobin, Luo, Wei, Wu, Zunyou

“…China’s methadone maintenance treatment program was initiated in 2004 as a small pilot project in just eight sites. It has since expanded into a nationwide…”
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Correction of RNA splicing defect in β 654 -thalassemia mice using CRISPR/Cas9 gene-editing technology by Lu, Dan, Gong, Xiuli, Fang, Yudan, Guo, Xinbing, Chen, Yanwen, Yang, Fan, Zhao, Guijun, Ma, Qingwen, Zeng, Yitao, Zeng, Fanyi

“…β654-thalassemia is a prominent Chinese subtype of b-thalassemia, representing 17% of all cases of β-thalassemia in China. The molecular mechanism underlying…”
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A self-deletion lentiviral vector to reduce the risk of replication-competent virus formation by Fang, Yudan, Gong, Xiuli, Xu, Miao, Zeng, Fanyi, Zhang, Jingzhi

“…Background Major improvements have been made progressively on human immunodeficiency virus (HIV)‐1 based lentiviral vectors to minimize the probability of…”
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Treatment of β654‐thalassaemia by TALENs in a mouse model by Fang, Yudan, Cheng, Yan, Lu, Dan, Gong, Xiuli, Yang, Guanheng, Gong, Zhijuan, Zhu, Yiwen, Sang, Xiao, Fan, Shuyue, Zhang, Jingzhi, Zeng, Fanyi

“…Objectives This study explored whether TALENs‐mediated non‐homologous end joining (NHEJ) targeting the mutation site can correct the aberrant β‐globin RNA…”
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Treatment of β 654 ‐thalassaemia by TALEN s in a mouse model by Fang, Yudan, Cheng, Yan, Lu, Dan, Gong, Xiuli, Yang, Guanheng, Gong, Zhijuan, Zhu, Yiwen, Sang, Xiao, Fan, Shuyue, Zhang, Jingzhi, Zeng, Fanyi

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Induction of protection against foot-and-mouth disease virus in cell culture and transgenic suckling mice by miRNA targeting integrin αv receptor by Du, Junzheng, Guo, Xinbing, Gao, Shandian, Luo, Jihuai, Gong, Xiuli, Hao, Chunxia, Yang, Bo, Lin, Tong, Shao, Junjun, Cong, Guozheng, Chang, Huiyun

“…•The expression of three αv-specific miRNAs targeting integrin αv receptor inhibited FMDV infection in cell culture.•Transgenic mice were generated by the…”
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A Herpes Simplex Virus Thymidine Kinase-Induced Mouse Model of Hepatocellular Carcinoma Associated with Up-Regulated Immune-Inflammatory-Related Signals by Gong, Zhijuan, Ma, Qingwen, Wang, Xujun, Cai, Qin, Gong, Xiuli, Genchev, Georgi Z, Lu, Hui, Zeng, Fanyi

“…Inflammation and fibrosis in human liver are often precursors to hepatocellular carcinoma (HCC), yet none of them is easily modeled in animals. We previously…”
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Efficient stabilization of recombinant human coagulation factor VIII in the milk of transgenic mice using hFVIII and vWF co-expression vector transduction by Ren, Xiaoye, Gong, Xiuli, Cai, Qin, Guo, Xinbing, Xu, Miao, Ren, Zhaorui, Zeng, Yitao

“…OBJECTIVES: To investigate the reasons for the instability of human coagulation factor FVIII (hFVIII) in milk which is an intractable obstacle during the…”
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Expression of human transferrin can be regulated effectively by rabbit transferrin regulatory elements in transgenic mice by Yan, Jingbin, Gong, Xiuli, Pan, Shubiao, Guo, Xinbing, Ren, Zhaorui, Zeng, Yitao

“…Human transferrin (hTF) belongs to the iron-binding glycoprotein family. It plays an important role in iron transport throughout the body. Transgenic mice are…”
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Analysis of different components in the peritumoral tissue microenvironment of colorectal cancer: A potential prospect in tumorigenesis by Huang, Chao, Liu, Hong, Gong, Xiuli, Wen, Bin, Chen, Dan, Liu, Jinyuan, Hu, Fengliang

“…The present study aimed to observe the varying expression of biomarkers in the microenvironment adjacent to colorectal cancer lesions to provide additional…”
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Analysis of different components in the peritumoral tissue microenvironment of colorectal cancer: A potential prospect in tumorigenesis by Huang, Chao, Liu, Hong, Gong, Xiuli, Wen, Bin, Chen, Dan, Liu, Jinyuan, Hu, Fengliang

“…Owing to an oversight during the proof checking stage, the above article has been published with the incorrect author listed for correspondence. The first…”
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