Search Results - "Gong, Weilong"

Mutation of the zebrafish nucleoporin elys sensitizes tissue progenitors to replication stress by Davuluri, Gangarao, Gong, Weilong, Yusuff, Shamila, Lorent, Kristin, Muthumani, Manimegalai, Dolan, Amy C, Pack, Michael

“…The recessive lethal mutation flotte lotte (flo) disrupts development of the zebrafish digestive system and other tissues. We show that flo encodes the…”
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The Nuclear Pore Complex Protein Elys Is Required for Genome Stability in Mouse Intestinal Epithelial Progenitor Cells by Gao, Nan, Davuluri, Gangarao, Gong, Weilong, Seiler, Christoph, Lorent, Kristin, Furth, Emma E, Kaestner, Klaus H, Pack, Michael

“…Background & Aims Elys is a conserved protein that directs nuclear pore complex (NPC) assembly in mammalian cell lines and developing worms and zebrafish…”
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Mutation of RNA Pol III subunit rpc2/polr3b Leads to Deficiency of Subunit Rpc11 and disrupts zebrafish digestive development by Yee, Nelson S, Gong, Weilong, Huang, Ying, Lorent, Kristin, Dolan, Amy C, Maraia, Richard J, Pack, Michael

“…The role of RNA polymerase III (Pol III) in developing vertebrates has not been examined. Here, we identify a causative mutation of the second largest Pol III…”
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Cloning a balanced translocation associated with DiGeorge syndrome and identification of a disrupted candidate gene by Budarf, Marcia L, Collins, Joelle, Gong, Weilong, Roe, Bruce, Wang, Zhili, Bailey, L. Charles, Sellinger, Bea, Michaud, Dominique, Driscoll, Deborah A, Emanuel, Beverly S

“…DiGeorge syndrome (DGS), a developmental defect, is characterized by cardiac defects and aplasia or hypoplasia of the thymus and parathyroid glands. DGS has…”
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Identification of a plant isoflavonoid that causes biliary atresia by Lorent, Kristin, Gong, Weilong, Koo, Kyung A, Waisbourd-Zinman, Orith, Karjoo, Sara, Zhao, Xiao, Sealy, Ian, Kettleborough, Ross N, Stemple, Derek L, Windsor, Peter A, Whittaker, Stephen J, Porter, John R, Wells, Rebecca G, Pack, Michael

“…Biliary atresia (BA) is a rapidly progressive and destructive fibrotic disorder of unknown etiology affecting the extrahepatic biliary tree of neonates…”
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A novel keratin18 promoter that drives reporter gene expression in the intrahepatic and extrahepatic biliary system allows isolation of cell-type specific transcripts from zebrafish liver by Wilkins, Benjamin J., Gong, Weilong, Pack, Michael

“…•A novel keratin18 promoter marks all biliary cells in transgenic zebrafish.•TRAP methodology can be used to recover polysome RNA from specific liver cell…”
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Biliatresone, a Reactive Natural Toxin from Dysphania glomulifera and D. littoralis: Discovery of the Toxic Moiety 1,2-Diaryl-2-Propenone by Koo, Kyung A, Lorent, Kristin, Gong, Weilong, Windsor, Peter, Whittaker, Stephen J, Pack, Michael, Wells, Rebecca G, Porter, John R

“…We identified a reactive natural toxin, biliatresone, from Dysphania glomulifera and D. littoralis collected in Australia that produces extrahepatic biliary…”
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TNFα-dependent hepatic steatosis and liver degeneration caused by mutation of zebrafish s-adenosylhomocysteine hydrolase by Matthews, Randolph P., Lorent, Kristin, Mañoral-Mobias, Rafael, Huang, Yuehua, Gong, Weilong, Murray, Ian V. J., Blair, Ian A., Pack, Michael

“…Hepatic steatosis and liver degeneration are prominent features of the zebrafish ducttrip (dtp) mutant phenotype. Positional cloning identified a causative…”
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Isolation and Characterization of a Gene from the DiGeorge Chromosomal Region Homologous to the MouseTbx1Gene by Chieffo, Carla, Garvey, Nancy, Gong, Weilong, Roe, Bruce, Zhang, Guozhong, Silver, Lee, Emanuel, Beverly S., Budarf, Marcia L.

“…DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome, and isolated and familial forms of conotruncal cardiac defects have been…”
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Mutation analysis of TBX1 in non-deleted patients with features of DGS/VCFS or isolated cardiovascular defects by Gong, Weilong, Gottlieb, Shoshanna, Collins, Joelle, Blescia, Adam, Dietz, Harry, Goldmuntz, Elizabeth, McDonald-McGinn, Donna M, Zackai, Elaine H, Emanuel, Beverly S, Driscoll, Deborah A, Budarf, Marcia L

“…In this study, only the exons and splice junctions ofTBX1 were screened. [...]mutations in the regulatory regions would be missed. [...]although TBX1 may be a…”
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Mutation of the Zebrafish Nucleoporin elys Sensitizes Tissue Progenitors to Replication Stress: e1000240 by Davuluri, Gangarao, Gong, Weilong, Yusuff, Shamila, Lorent, Kristin, Muthumani, Manimegalai, Dolan, Amy C, Pack, Michael

“…The recessive lethal mutation flotte lotte (flo) disrupts development of the zebrafish digestive system and other tissues. We show that flo encodes the…”
Get full text

TNFalpha-dependent hepatic steatosis and liver degeneration caused by mutation of zebrafish S-adenosylhomocysteine hydrolase by Matthews, Randolph P, Lorent, Kristin, Mañoral-Mobias, Rafael, Huang, Yuehua, Gong, Weilong, Murray, Ian V J, Blair, Ian A, Pack, Michael

“…Hepatic steatosis and liver degeneration are prominent features of the zebrafish ducttrip (dtp) mutant phenotype. Positional cloning identified a causative…”
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TNFα-dependent hepatic steatosis and liver degeneration caused by mutation of zebrafish s-adenosylhomocysteine hydrolase by Randolph P. Matthews, Kristin Lorent, Rafael Mañoral-Mobias, Yuehua Huang, Weilong Gong, Ian V. J. Murray, Ian A. Blair, Michael Pack

“…Hepatic steatosis and liver degeneration are prominent features of the zebrafish ducttrip ( dtp ) mutant phenotype. Positional cloning identified a causative…”
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Isolation and characterization of a gene from the DiGeorge chromosomal region homologous to the mouse Tbx1 gene by CHIEFFO, C, GARVEY, N, GONG, W, ROE, B, ZHANG, G, SILVER, L, EMANUEL, B. S, BUDARF, M. L

“…DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome, and isolated and familial forms of conotruncal cardiac defects have been…”
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A transcription map of the DiGeorge and velo-cardio-facial syndrome minimal critical region on 22q11 by GONG, W, EMANUEL, B. S, COLLINS, J, KIM, D. H, WANG, Z, CHEN, F, ZHANG, G, ROE, B, BUDARF, M. L

“…The majority of patients with DiGeorge syndrome (DGS) and velo-cardio-facial syndrome (VCFS) have a microdeletion of 22q11. Using translocation breakpoints and…”
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A region of mouse chromosome 16 is syntenic to the DiGeorge, velocardiofacial syndrome minimal critical region by Galili, N, Baldwin, H S, Lund, J, Reeves, R, Gong, W, Wang, Z, Roe, B A, Emanuel, B S, Nayak, S, Mickanin, C, Budarf, M L, Buck, C A

“…DGS and VCFS, haploinsufficiencies characterized by multiple craniofacial and cardiac abnormalities, are associated with a microdeletion of chromosome 22q11.2…”
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Isolation of human and mouse HMG2a cDNAs: evidence for an HMG2a-specific 3′ untranslated region by Wilke, Klaus, Wiemann, Stefan, Gaul, Renate, Gong, Weilong, Poustka, Annemarie

“…We have isolated cDNAs of the human gene for high mobility group protein HMG2a, using the method of direct cDNA selection. The gene maps to chromosome band…”
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Disruption of the Clathrin Heavy Chain-Like Gene (CLTCL) Associated with Features of DGS/VCFS: A Balanced (21;22)(p12;q11) Translocation by Holmes, Susan E., Riazi, M. Ali, Gong, Weilong, McDermid, Heather E., Sellinger, Beatrice T., Hua, Axin, Chen, Feng, Wang, Zhili, Zhang, Guozhang, Roe, Bruce, Gonzalez, Iris, McDonald-McGinn, Donna M., Zackai, Elaine, Emanuel, Beverly S., Budarf, Marcia L.

“…The smallest region of deletion overlap in the patients we have studied defines a DiGeorge syndrome/velocardiofacial syndrome (DGS/VCFS) minimal critical…”
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Structural and Mutational Analysis of a Conserved Gene (DGSI) from the Minimal DiGeorge Syndrome Critical Region by Gong, Weilong, Emanuel, Beverly S., Galili, Naomi, Kim, David H., Roe, Bruce, Driscoll, Deborah A., Budarf, Marcia L.

“…The majority of patients with DiGeorge syndrome (DGS), velocardiofacial syndr ome (VCFS), conotruncal anomaly face syndrome (CTAFS) and some individuals with…”
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A Transcription Map of the Digeorge and Velo-Ardio-Facial Syndrome Minimal Critical Region on 22q11 by Gong, Weilong, Emanuel, Beverly S., Collins, Joelle, Kim, David H., Wang, Zhili, Chen, Feng, Zhang, Guozhong, Roe, Bruce, Budarf, Marcia L.

“…The majority of patients with DiGeorge syndrome (DGS) and velo-cardio-facial syndrome (VCFS) have a microdeletion of 22q11. Using translocation breapoints and…”
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