Search Results - "Gong, Sitang"

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  1. 1

    Characteristics of pediatric SARS-CoV-2 infection and potential evidence for persistent fecal viral shedding by Xu, Yi, Li, Xufang, Zhu, Bing, Liang, Huiying, Fang, Chunxiao, Gong, Yu, Guo, Qiaozhi, Sun, Xin, Zhao, Danyang, Shen, Jun, Zhang, Huayan, Liu, Hongsheng, Xia, Huimin, Tang, Jinling, Zhang, Kang, Gong, Sitang

    Published in Nature medicine (01-04-2020)
    “…We report epidemiological and clinical investigations on ten pediatric SARS-CoV-2 infection cases confirmed by real-time reverse transcription PCR assay of…”
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  2. 2

    PKN2 in colon cancer cells inhibits M2 phenotype polarization of tumor-associated macrophages via regulating DUSP6-Erk1/2 pathway by Cheng, Yang, Zhu, Yun, Xu, Jiajia, Yang, Min, Chen, Peiyu, Xu, Wanfu, Zhao, Junhong, Geng, Lanlan, Gong, Sitang

    Published in Molecular cancer (24-01-2018)
    “…Protein kinase N2 (PKN2) is a PKC-related serine/threonine-protein kinase. PKN2 is required for tumor cell migration, invasion and apoptosis. However, the…”
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    Functional and structural characterization of a two-MAb cocktail for delayed treatment of enterovirus D68 infections by Zhang, Chao, Xu, Cong, Dai, Wenlong, Wang, Yifan, Liu, Zhi, Zhang, Xueyang, Wang, Xuesong, Wang, Haikun, Gong, Sitang, Cong, Yao, Huang, Zhong

    Published in Nature communications (18-05-2021)
    “…Enterovirus D68 (EV-D68) is an emerging pathogen associated with respiratory diseases and/or acute flaccid myelitis. Here, two MAbs, 2H12 and 8F12, raised…”
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  5. 5

    Identification of candidate diagnostic and prognostic biomarkers for pancreatic carcinoma by Cheng, Yang, Wang, Kunyuan, Geng, Lanlan, Sun, Jingjing, Xu, Wanfu, Liu, Dingli, Gong, Sitang, Zhu, Yun

    Published in EBioMedicine (01-02-2019)
    “…Pancreatic carcinoma (PC) is one of the most aggressive cancers affecting human health. It is essential to identify candidate biomarkers for the diagnosis and…”
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  6. 6

    SLAMF7 regulates the inflammatory response in macrophages during polymicrobial sepsis by Wu, Yongjian, Wang, Qiaohua, Li, Miao, Lao, Juanfeng, Tang, Huishu, Ming, Siqi, Wu, Minhao, Gong, Sitang, Li, Linhai, Liu, Lei, Huang, Xi

    Published in The Journal of clinical investigation (15-03-2023)
    “…Uncontrolled inflammation occurred in sepsis results in multiple organ injuries and shock, which contributes to the death of patients with sepsis. However, the…”
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  7. 7

    MiR-1 suppresses tumor cell proliferation in colorectal cancer by inhibition of Smad3-mediated tumor glycolysis by Xu, Wanfu, Zhang, Zijing, Zou, Kejian, Cheng, Yang, Yang, Min, Chen, Huan, Wang, Hongli, Zhao, Junhong, Chen, Peiyu, He, Liying, Chen, Xinwen, Geng, Lanlan, Gong, Sitang

    Published in Cell death & disease (04-05-2017)
    “…Aberrant expression of microRNA (miR)-1 has been observed in many human malignancies. However, the function and underlying mechanism of miR-1 remains elusive…”
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  8. 8

    Salmonella effector SopB reorganizes cytoskeletal vimentin to maintain replication vacuoles for efficient infection by Zhao, Shuangshuang, Xu, Qiuping, Cui, Yanqin, Yao, Su, Jin, Sihui, Zhang, Qian, Wen, Zeyu, Ruan, Haihua, Liang, Xin, Chao, Yanjie, Gong, Sitang, Sansonetti, Philippe, Wei, Ke, Tang, Hong, Jiu, Yaming

    Published in Nature communications (30-01-2023)
    “…A variety of intracellular bacteria modulate the host cytoskeleton to establish subcellular niches for replication. However, the role of intermediate…”
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  9. 9

    Mast cells-derived MiR-223 destroys intestinal barrier function by inhibition of CLDN8 expression in intestinal epithelial cells by Li, Musheng, Zhao, Junhong, Cao, Meiwan, Liu, Ruitao, Chen, Guanhua, Li, Songyu, Xie, Yuanwen, Xie, Jing, Cheng, Yang, Huang, Ling, Su, Mingmin, Xu, Yuxin, Zheng, Mingyue, Zou, Kejian, Geng, Lanlan, Xu, Wanfu, Gong, Sitang

    Published in Biological research (24-03-2020)
    “…Mast cells (MCs) have been found to play a critical role during development of inflammatory bowel disease (IBD) that characterized by dysregulation of…”
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  10. 10

    GITR Promotes the Polarization of TFH-Like Cells in Helicobacter pylori -Positive Gastritis by Ming, Siqi, Yin, Huan, Li, Xingyu, Gong, Sitang, Zhang, Guoliang, Wu, Yongjian

    Published in Frontiers in immunology (10-09-2021)
    “…Gastric CD4 T cells contribute to ( )-induced gastritis by amplifying mucosal inflammation and exacerbating mucosal injuries. However, the pathogenic CD4 T…”
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  11. 11

    Aminophylline suppresses chronic renal failure progression by activating SIRT1/AMPK/mTOR-dependent autophagy by Liao, Xin, Lu, Jieyi, Huang, Zhifeng, Lin, Jinai, Zhang, Miao, Chen, Huanru, Lin, Xiaoqing, Gao, Xia, Gong, Sitang

    Published in Acta biochimica et biophysica Sinica (28-05-2024)
    “…Chronic renal failure (CRF) is a severe syndrome affecting the urinary system for which there are no effective therapeutics. In this study, we investigate the…”
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  12. 12

    Human Norovirus NTPase Antagonizes Interferon-β Production by Interacting With IkB Kinase ε by Zheng, Zifeng, Li, Yuncheng, Zhang, Mudan, Liu, Yalan, Fu, Ming, Gong, Sitang, Hu, Qinxue

    Published in Frontiers in microbiology (15-07-2021)
    “…Human norovirus (HuNoV) is the leading cause of epidemic acute gastroenteritis worldwide. Type I interferons (IFN)-α/β are highly potent cytokines that are…”
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  13. 13

    Zika Virus Infection Induces Acute Kidney Injury Through Activating NLRP3 Inflammasome Via Suppressing Bcl-2 by Liu, Ting, Tang, Lantian, Tang, Hui, Pu, Jieying, Gong, Sitang, Fang, Danyun, Zhang, Hui, Li, Yi-Ping, Zhu, Xun, Wang, Weidong, Wu, Minhao, Liao, Yuhui, Li, Chunling, Zhou, Haibo, Huang, Xi

    Published in Frontiers in immunology (14-08-2019)
    “…Zika virus (ZIKV) is a newly emerging flavivirus that broadly exhibits in various bodily tissues and fluids, especially in the brain, and ZIKV infection often…”
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  14. 14

    Vitronectin Destroyed Intestinal Epithelial Cell Differentiation through Activation of PDE4-Mediated Ferroptosis in Inflammatory Bowel Disease by Pan, Wenxu, Xiang, Li, Liang, Xinhua, Du, Wenjun, Zhao, Junhong, Zhang, Song, Zhou, Xuan, Geng, Lanlan, Gong, Sitang, Xu, Wanfu

    Published in Mediators of inflammation (19-07-2023)
    “…Objective. Vitronectin (VTN) has been reported to trigger cell pyroptosis to aggravate inflammation in our previous study. However, the function of VTN in…”
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  15. 15

    Sorbitol Destroyed Intestinal Microfold Cells (M Cells) Development through Inhibition of PDE4-Mediated RANKL Expression by Xiang, Li, Pan, Wenxu, Chen, Huan, Du, Wenjun, Xie, Shuping, Liang, Xinhua, Yang, Fangying, Niu, Rongwei, Huang, Canxin, Luo, Minan, Xu, Yuxin, Geng, Lanlan, Gong, Sitang, Xu, Wanfu, Zhao, Junhong

    Published in Mediators of inflammation (02-05-2024)
    “…Objective. Microfold cells (M cells) are specific intestinal epithelial cells for monitoring and transcytosis of antigens, microorganisms, and pathogens in the…”
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  16. 16

    Deficiency of GntR Family Regulator MSMEG_5174 Promotes Mycobacterium smegmatis Resistance to Aminoglycosides via Manipulating Purine Metabolism by Deng, Wanyan, Zheng, Zengzhang, Chen, Yi, Yang, Maoyi, Yan, Jun, Li, Wu, Zeng, Jie, Xie, Jianping, Gong, Sitang, Zeng, Huasong

    Published in Frontiers in microbiology (11-07-2022)
    “…The increasing incidence of drug-resistant tuberculosis is still an emergency for global public health and a major obstacle to tuberculosis treatment…”
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  17. 17

    Lactose intolerance and gastrointestinal cow's milk allergy in infants and children - common misconceptions revisited by Heine, Ralf G, AlRefaee, Fawaz, Bachina, Prashant, De Leon, Julie C, Geng, Lanlan, Gong, Sitang, Madrazo, José Armando, Ngamphaiboon, Jarungchit, Ong, Christina, Rogacion, Jossie M

    Published in The World Allergy Organization journal (12-12-2017)
    “…Lactose is the main carbohydrate in human and mammalian milk. Lactose requires enzymatic hydrolysis by lactase into D-glucose and D-galactose before it can be…”
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  18. 18

    Monocarboxylate Transporter 4 Triggered Cell Pyroptosis to Aggravate Intestinal Inflammation in Inflammatory Bowel Disease by Wang, Yaodong, Zhou, Xiaorong, Zou, Kejian, Chen, Guanhua, Huang, Ling, Yang, Fangying, Pan, Wenxu, Xu, Hongwei, Xu, Zhaohui, Chen, Huan, Chen, Jiayu, Gong, Sitang, Zhou, Xuan, Xu, Wanfu, Zhao, Junhong

    Published in Frontiers in immunology (19-05-2021)
    “…NLRP3 inflammasome has emerged as a crucial regulator of inflammatory bowel disease (IBD) characterized by a chronic inflammatory disease of the…”
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  19. 19

    A Mouse Model of Enterovirus D68 Infection for Assessment of the Efficacy of Inactivated Vaccine by Zhang, Chao, Zhang, Xueyang, Dai, Wenlong, Liu, Qingwei, Xiong, Pei, Wang, Shuxia, Geng, Lanlan, Gong, Sitang, Huang, Zhong

    Published in Viruses (30-01-2018)
    “…In recent years, enterovirus D68 (EVD68) has been reported increasingly to be associated with severe respiratory tract infections and acute flaccid myelitis…”
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