Search Results - "Gong, Hong"

The Role of HOX Transcription Factors in Cancer Predisposition and Progression by Li, Bo, Huang, Qilai, Wei, Gong-Hong

“…Homeobox (HOX) transcription factors, encoded by a subset of homeodomain superfamily genes, play pivotal roles in many aspects of cellular physiology,…”
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Human transcription factor protein interaction networks by Göös, Helka, Kinnunen, Matias, Salokas, Kari, Tan, Zenglai, Liu, Xiaonan, Yadav, Leena, Zhang, Qin, Wei, Gong-Hong, Varjosalo, Markku

“…Transcription factors (TFs) interact with several other proteins in the process of transcriptional regulation. Here, we identify 6703 and 1536 protein–protein…”
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Genomic Insight into the Role of lncRNAs in Cancer Susceptibility by Gao, Ping, Wei, Gong-Hong

“…With the development of advanced genomic methods, a large amount of long non-coding RNAs (lncRNAs) have been found to be important for cancer initiation and…”
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Palmitic acid is an intracellular signaling molecule involved in disease development by Fatima, Sarwat, Hu, Xianjing, Gong, Rui-Hong, Huang, Chunhua, Chen, Minting, Wong, Hoi Leong Xavier, Bian, Zhaoxiang, Kwan, Hiu Yee

“…Emerging evidence shows that palmitic acid (PA), a common fatty acid in the human diet, serves as a signaling molecule regulating the progression and…”
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Genomic Insight into the Role of lncRNA in Cancer Susceptibility by Gao, Ping, Wei, Gong-Hong

“…With the development of advanced genomic methods, a large amount of long non-coding RNAs (lncRNAs) has been found to be important for cancer initiation and…”
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Mechanistic insights into genetic susceptibility to prostate cancer by Tian, Pan, Zhong, Mengjie, Wei, Gong-Hong

“…Prostate cancer (PCa) is the second most common cancer in men and is a highly heritable disease that affects millions of individuals worldwide. Genome-wide…”
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SNHG15‐mediated feedback loop interplays with HNRNPA1/SLC7A11/GPX4 pathway to promote gastric cancer progression by Duan, Yantao, Yan, Yonghao, Fu, Hongbing, Dong, Yang, Li, Kun, Ye, Zaisheng, Dou, Yi, Huang, Binhao, Kang, Wei, Wei, Gong‐Hong, Cai, Qiliang, Xu, Dazhi, Zhou, Donglei

“…Dysregulation of long noncoding RNA (lncRNA) expression plays a pivotal role in the initiation and progression of gastric cancer (GC). However, the regulation…”
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Systematic identification of regulatory variants associated with cancer risk by Liu, Song, Liu, Yuwen, Zhang, Qin, Wu, Jiayu, Liang, Junbo, Yu, Shan, Wei, Gong-Hong, White, Kevin P, Wang, Xiaoyue

“…Most cancer risk-associated single nucleotide polymorphisms (SNPs) identified by genome-wide association studies (GWAS) are noncoding and it is challenging to…”
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Combined CRISPRi and proteomics screening reveal a cohesin-CTCF-bound allele contributing to increased expression of RUVBL1 and prostate cancer progression by Tian, Yijun, Dong, Dandan, Wang, Zixian, Wu, Lang, Park, Jong Y., Wei, Gong-Hong, Wang, Liang

“…Genome-wide association studies along with expression quantitative trait locus (eQTL) mapping have identified hundreds of single-nucleotide polymorphisms…”
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A review on the pharmacokinetics of paeoniflorin and its anti-inflammatory and immunomodulatory effects by Zhou, Yan-Xi, Gong, Xiao-Hong, Zhang, Hong, Peng, Cheng

“…[Display omitted] •Paeoniflorin is mainly metabolized in intestinal bacteria.•The low bioavailability of paeoniflorin can be improved by certain…”
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DNA methylation modulated genetic variant effect on gene transcriptional regulation by Zeng, Yong, Jain, Rahi, Lam, Magnus, Ahmed, Musaddeque, Guo, Haiyang, Xu, Wenjie, Zhong, Yuan, Wei, Gong-Hong, Xu, Wei, He, Housheng Hansen

“…Expression quantitative trait locus (eQTL) analysis has emerged as an important tool in elucidating the link between genetic variants and gene expression,…”
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High-throughput screening of prostate cancer risk loci by single nucleotide polymorphisms sequencing by Zhang, Peng, Xia, Ji-Han, Zhu, Jing, Gao, Ping, Tian, Yi-Jun, Du, Meijun, Guo, Yong-Chen, Suleman, Sufyan, Zhang, Qin, Kohli, Manish, Tillmans, Lori S., Thibodeau, Stephen N., French, Amy J., Cerhan, James R., Wang, Li-Dong, Wei, Gong-Hong, Wang, Liang

“…Functional characterization of disease-causing variants at risk loci has been a significant challenge. Here we report a high-throughput single-nucleotide…”
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A long hypoxia-inducible factor 3 isoform 2 is a transcription activator that regulates erythropoietin by Tolonen, Jussi-Pekka, Heikkilä, Minna, Malinen, Marjo, Lee, Hang-Mao, Palvimo, Jorma J., Wei, Gong-Hong, Myllyharju, Johanna

“…Hypoxia-inducible factor (HIF), an αβ dimer, is the master regulator of oxygen homeostasis with hundreds of hypoxia-inducible target genes. Three HIF isoforms…”
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Genome-wide analysis of ETS-family DNA-binding in vitro and in vivo by Wei, Gong-Hong, Badis, Gwenael, Berger, Michael F, Kivioja, Teemu, Palin, Kimmo, Enge, Martin, Bonke, Martin, Jolma, Arttu, Varjosalo, Markku, Gehrke, Andrew R, Yan, Jian, Talukder, Shaheynoor, Turunen, Mikko, Taipale, Mikko, Stunnenberg, Hendrik G, Ukkonen, Esko, Hughes, Timothy R, Bulyk, Martha L, Taipale, Jussi

“…Members of the large ETS family of transcription factors (TFs) have highly similar DNA‐binding domains (DBDs)—yet they have diverse functions and activities in…”
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Comprehensive assessment of cellular senescence in the tumor microenvironment by Wang, Xiaoman, Ma, Lifei, Pei, Xiaoya, Wang, Heping, Tang, Xiaoqiang, Pei, Jian-Fei, Ding, Yang-Nan, Qu, Siyao, Wei, Zi-Yu, Wang, Hui-Yu, Wang, Xiaoyue, Wei, Gong-Hong, Liu, De-Pei, Chen, Hou-Zao

“…Abstract Cellular senescence (CS), a state of permanent growth arrest, is intertwined with tumorigenesis. Due to the absence of specific markers,…”
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Biology and Clinical Implications of the 19q13 Aggressive Prostate Cancer Susceptibility Locus by Gao, Ping, Xia, Ji-Han, Sipeky, Csilla, Dong, Xiao-Ming, Zhang, Qin, Yang, Yuehong, Zhang, Peng, Cruz, Sara Pereira, Zhang, Kai, Zhu, Jing, Lee, Hang-Mao, Suleman, Sufyan, Giannareas, Nikolaos, Liu, Song, Tammela, Teuvo L.J., Auvinen, Anssi, Wang, Xiaoyue, Huang, Qilai, Wang, Liguo, Manninen, Aki, Vaarala, Markku H., Wang, Liang, Schleutker, Johanna, Wei, Gong-Hong

“…Genome-wide association studies (GWAS) have identified rs11672691 at 19q13 associated with aggressive prostate cancer (PCa). Here, we independently confirmed…”
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CRISPRi screens reveal a DNA methylation-mediated 3D genome dependent causal mechanism in prostate cancer by Ahmed, Musaddeque, Soares, Fraser, Xia, Ji-Han, Yang, Yue, Li, Jing, Guo, Haiyang, Su, Peiran, Tian, Yijun, Lee, Hyung Joo, Wang, Miranda, Akhtar, Nayeema, Houlahan, Kathleen E., Bosch, Almudena, Zhou, Stanley, Mazrooei, Parisa, Hua, Junjie T., Chen, Sujun, Petricca, Jessica, Zeng, Yong, Davies, Alastair, Fraser, Michael, Quigley, David A., Feng, Felix Y., Boutros, Paul C., Lupien, Mathieu, Zoubeidi, Amina, Wang, Liang, Walsh, Martin J., Wang, Ting, Ren, Shancheng, Wei, Gong-Hong, He, Housheng Hansen

“…Prostate cancer (PCa) risk-associated SNPs are enriched in noncoding cis-regulatory elements (rCREs), yet their modi operandi and clinical impact remain…”
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Long-distance free-space quantum key distribution in daylight towards inter-satellite communication by Liao, Sheng-Kai, Yong, Hai-Lin, Liu, Chang, Shentu, Guo-Liang, Li, Dong-Dong, Lin, Jin, Dai, Hui, Zhao, Shuang-Qiang, Li, Bo, Guan, Jian-Yu, Chen, Wei, Gong, Yun-Hong, Li, Yang, Lin, Ze-Hong, Pan, Ge-Sheng, Pelc, Jason S., Fejer, M. M., Zhang, Wen-Zhuo, Liu, Wei-Yue, Yin, Juan, Ren, Ji-Gang, Wang, Xiang-Bin, Zhang, Qiang, Peng, Cheng-Zhi, Pan, Jian-Wei

“…In the past, long-distance free-space quantum communication experiments could only be implemented at night. During the daytime, the bright background sunlight…”
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Machine learning-based brief version of the Caregiver-Teacher Report Form for preschoolers by Lin, Gong-Hong, Lee, Shih-Chieh, Yu, Yen-Ting, Huang, Chien-Yu

“…The Caregiver-Teacher Report Form of the Child Behavior Checklist for Ages 1½–5 (C-TRF) is a widely used checklist to identify emotional and behavioral…”
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A Monte Carlo and PSO based virtual sample generation method for enhancing the energy prediction and energy optimization on small data problem: An empirical study of petrochemical industries by Gong, Hong-Fei, Chen, Zhong-Sheng, Zhu, Qun-Xiong, He, Yan-Lin

“…•A novel Monte Carlo and PSO based virtual sample generation method is proposed.•Effective virtual samples are generated for solving the small data…”
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