Search Results - "Gong, Fanglin"

AGILE platform: a deep learning powered approach to accelerate LNP development for mRNA delivery by Xu, Yue, Ma, Shihao, Cui, Haotian, Chen, Jingan, Xu, Shufen, Gong, Fanglin, Golubovic, Alex, Zhou, Muye, Wang, Kevin Chang, Varley, Andrew, Lu, Rick Xing Ze, Wang, Bo, Li, Bowen

“…Ionizable lipid nanoparticles (LNPs) are seeing widespread use in mRNA delivery, notably in SARS-CoV-2 mRNA vaccines. However, the expansion of mRNA therapies…”
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Poly-β-cyclodextrin Supramolecular Nanoassembly with a pH-Sensitive Switch Removing Lysosomal Cholesterol Crystals for Antiatherosclerosis by Zhang, Yan, Gong, Fanglin, Wu, Yue, Hou, Siyuan, Xue, Lingjing, Su, Zhigui, Zhang, Can

“…Cholesterol crystals (CCs), originally accumulating in the lysosome of cholesterol-laden cells, can aggravate the progression of atherosclerosis…”
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An elastase-inhibiting, plaque-targeting and neutrophil-hitchhiking liposome against atherosclerosis by Shi, Yin, Dong, Mei, Wu, Yue, Gong, Fanglin, Wang, Zibin, Xue, Lingjing, Su, Zhigui

“…Neutrophil extracellular traps (NETs) play a crucial role in the formation of vulnerable plaques and the development of atherosclerosis. Alleviating the…”
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The Impaired Mechanism and Facilitated Therapies of Efferocytosis in Atherosclerosis by Wang, Zibin, Su, Jin, Gong, Fanglin, Xue, Lingjing, Su, Zhigui

“…Cardiovascular disease is responsible for the largest number of deaths worldwide, and atherosclerosis is the primary cause. Apoptotic cell accumulation in…”
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The Impaired Mechanism and Facilitated Therapies of Efferocytosis in Atherosclerosis by Zibin, Wang, Jin, Su, Fanglin, Gong, Lingjing, Xue, Zhigui, Su

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Nano-sponge-like liposomes remove cholesterol crystals for antiatherosclerosis by Gong, Fanglin, Wang, Zibin, Mo, Rui, Wang, Yutong, Su, Jin, Li, Xianglong, Omonova, Charos Tuychi Qizi, Khamis, Amari Mohamed, Zhang, Qing, Dong, Mei, Su, Zhigui

“…Atherosclerotic cardiovascular diseases remain the leading causes of morbidity and mortality worldwide. Cholesterol crystals in atherosclerotic plaques play an…”
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Tumor‐Tailored Ionizable Lipid Nanoparticles Facilitate IL‐12 Circular RNA Delivery for Enhanced Lung Cancer Immunotherapy by Xu, Shufen, Xu, Yue, Solek, Nicholas C., Chen, Jingan, Gong, Fanglin, Varley, Andrew James, Golubovic, Alex, Pan, Anni, Dong, Songtao, Zheng, Gang, Li, Bowen

“…The advancement of message RNA (mRNA) ‐based immunotherapies for cancer is highly dependent on the effective delivery of RNA (Ribonucleic) payloads using…”
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Tumor‐Tailored Ionizable Lipid Nanoparticles Facilitate IL‐12 Circular RNA Delivery for Enhanced Lung Cancer Immunotherapy (Adv. Mater. 29/2024) by Xu, Shufen, Xu, Yue, Solek, Nicholas C., Chen, Jingan, Gong, Fanglin, Varley, Andrew James, Golubovic, Alex, Pan, Anni, Dong, Songtao, Zheng, Gang, Li, Bowen

“…Inhalable RNA Immunotherapy In article number 2400307, Bowen Li and co‐workers develop a tumor‐tailored lipid nanoparticle system to deliver IL‐12 circular RNA…”
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