Search Results - "Gondek, David C"

Cutting Edge: Contact-Mediated Suppression by CD4+CD25+ Regulatory Cells Involves a Granzyme B-Dependent, Perforin-Independent Mechanism by Gondek, David C, Lu, Li-Fan, Quezada, Sergio A, Sakaguchi, Shimon, Noelle, Randolph J

“…CD4+CD25+ regulatory T cells (Treg) are potent immunosuppressive cells that are pivotal in the regulation of peripheral tolerance. In this report, we identify…”
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CD4+ T cells are necessary and sufficient to confer protection against Chlamydia trachomatis infection in the murine upper genital tract by Gondek, David C, Olive, Andrew J, Stary, Georg, Starnbach, Michael N

“…Chlamydia trachomatis infection is the most common bacterial sexually transmitted disease in the United States. Chlamydia infections that ascend to the upper…”
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Mast cells are essential intermediaries in regulatory T-cell tolerance by Van Snick, Jacques, Noelle, Randolph J, Gondek, David C, Lind, Evan F, Strom, Terry B, Zheng, Xin Xiao, Gleeson, Michael W, Pino-Lagos, Karina, Scott, Zachary A, Bennett, Kathy A, Lu, Li-Fan, Reed, Jennifer L, Coyle, Anthony J

“…Contrary to the proinflammatory role of mast cells in allergic disorders, the results obtained in this study establish that mast cells are essential in…”
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T cell responses in the absence of IFN-gamma exacerbate uterine infection with Chlamydia trachomatis by Gondek, David C, Roan, Nadia R, Starnbach, Michael N

“…Infection with the obligate intracellular bacterium Chlamydia trachomatis is controlled primarily by IFN-gamma and Th1 immunity. In this study, we used cells…”
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Transplantation Survival Is Maintained by Granzyme B+ Regulatory Cells and Adaptive Regulatory T Cells by Gondek, David C, DeVries, Victor, Nowak, Elizabeth C, Lu, Li-Fan, Bennett, Kathryn A, Scott, Zachary A, Noelle, Randolph J

“…Granzyme B (GZB) has been implicated as an effector mechanism in regulatory T cells (T(reg)) suppression. In a model of T(reg)-dependent graft tolerance, it is…”
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Chlamydia Infection Across Host Species Boundaries Promotes Distinct Sets of Transcribed Anti-Apoptotic Factors by Messinger, Joshua E, Nelton, Emmalin, Feeney, Colleen, Gondek, David C

“…Chlamydiae, obligate intracellular bacteria, cause significant human and veterinary associated diseases. Having emerged an estimated 700-million years ago,…”
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NF kappa B-inducing kinase deficiency results in the development of a subset of regulatory T cells, which shows a hyperproliferative activity upon glucocorticoid-induced TNF receptor family-related gene stimulation by Lu, Li-Fan, Gondek, David C, Scott, Zachary A, Noelle, Randolph J

“…CD4+CD25+ regulatory T cells (T(reg)) play an important role in maintaining immunologic tolerance. Glucocorticoid-induced TNFR family-related gene (GITR)…”
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Different Functional Capacities of Latent and Lytic Antigen-Specific CD8 T Cells in Murine Gammaherpesvirus Infection by Obar, Joshua J, Crist, Sarah G, Gondek, David C, Usherwood, Edward J

“…Gammaherpesviruses can persist in the host in the face of an aggressive immune response. T cells recognize Ags expressed in both the productive and latent…”
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CXCR3 and CCR5 are both required for T cell-mediated protection against C. trachomatis infection in the murine genital mucosa by Olive, A J, Gondek, D C, Starnbach, M N

“…Chemokine receptors direct T lymphocytes to the site of an infection by following coordinated chemokine gradients, which allow their recruitment to specific…”
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CD4+ T cells are necessary and sufficient to confer protection against C. trachomatis infection in the murine upper genital tract by Gondek, David C., Olive, Andrew J., Stary, Georg, Starnbach, Michael N.

“…Chlamydia trachomatis infection is the most common bacterial sexually transmitted disease in the United States. Chlamydia infections that ascend to the upper…”
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Analysis of Watson's Strategies for Playing Jeopardy by Tesauro, G., Gondek, D. C., Lenchner, J., Fan, J., Prager, J. M.

“…Major advances in Question Answering technology were needed for IBM Watson to play Jeopardy! at championship level -- the show requires rapid-fire answers to…”
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Contact-Mediated Suppression by CD4 super(+)CD25 super(+) Regulatory Cells Involves a Granzyme B-Dependent, Perforin-Independent Mechanism by Gondek, David C, Lu, Li-Fan, Quezada, Sergio A, Sakaguchi, Shimon, Noelle, Randolph J

“…CD4 super(+)CD25 super(+) regulatory T cells (T sub(reg)) are potent immunosuppressive cells that are pivotal in the regulation of peripheral tolerance. In…”
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Different Functional Capacities of Latent and Lytic Antigen-Specific CD8 T Cells in Murine Gammaherpesvirus Infection1 by Obar, Joshua J., Crist, Sarah G., Gondek, David C., Usherwood, Edward J.

“…Gammaherpesviruses can persist in the host in the face of an aggressive immune response. T cells recognize Ags expressed in both the productive and latent…”
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T Cell Responses in the Absence of IFN-{gamma} Exacerbate Uterine Infection with Chlamydia trachomatis by Gondek, David C, Roan, Nadia R, Starnbach, Michael N

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Analysis of Watson's Strategies for Playing Jeopardy by Tesauro, Gerald, Gondek, David C, Lenchner, Jonathan, Fan, James, Prager, John M

“…Journal Of Artificial Intelligence Research, Volume 47, pages 205-251, 2013 Major advances in Question Answering technology were needed for IBM Watson to play…”
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NF{kappa}B-Inducing Kinase Deficiency Results in the Development of a Subset of Regulatory T Cells, which Shows a Hyperproliferative Activity upon Glucocorticoid-Induced TNF Receptor Family-Related Gene Stimulation by Lu, Li-Fan, Gondek, David C, Scott, Zachary A, Noelle, Randolph J

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