Search Results - "Gondas, Eduard"

Effects of TRPV4 channel blocker on airway inflammation and airway defense reflexes in experimentally induced model of allergic asthma by Mažerik, Jozef, Gondáš, Eduard, Smieško, Lukáš, Fraňová, Soňa, Šutovská, Martina

“…The transient receptor potential (TRP) channels regulate physiological and pathological processes. Changes in their activity and sensitivity may be involved in…”
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Application of the Hydrophilic Interaction Liquid Chromatography (HILIC-MS) Novel Protocol to Study the Metabolic Heterogeneity of Glioblastoma Cells by Šofranko, Jakub, Gondáš, Eduard, Murín, Radovan

“…Glioblastoma is a highly malignant brain tumor consisting of a heterogeneous cellular population. The transformed metabolism of glioblastoma cells supports…”
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Targeting TMEM16A ion channels suppresses airway hyperreactivity, inflammation, and remodeling in an experimental Guinea pig asthma model by Mažerik, Jozef, Gondáš, Eduard, Dohál, Matúš, Smieško, Lukáš, Jošková, Marta, Fraňová, Soňa, Šutovská, Martina

“…Asthma is a chronic inflammatory disease characterized by airway hyperresponsiveness, inflammation, and remodeling. Calcium (Ca2+)-activated chloride (Cl−)…”
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Both Enantiomers of 2-Hydroxyglutarate Modulate the Metabolism of Cultured Human Neuroblastoma Cells by Gondáš, Eduard, Baranovičová, Eva, Bystrický, Peter, Šofranko, Jakub, Evinová, Andrea, Dohál, Matúš, Hatoková, Zuzana, Murín, Radovan

“…Elevated levels of D-2-hydroxyglutarate (D-2HG) and L-2-hydroxyglutarate (L-2HG) in the brain are associated with various pathological conditions, potentially…”
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Hyperglycemia Stimulates the Irreversible Catabolism of Branched-Chain Amino Acids and Generation of Ketone Bodies by Cultured Human Astrocytes by Gondáš, Eduard, Baranovičová, Eva, Šofranko, Jakub, Murín, Radovan

“…Astrocytes are considered to possess a noticeable role in brain metabolism and, as a partners in neuron-glia cooperation, to contribute to the synthesis,…”
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Immunodetection of Pyruvate Carboxylase Expression in Human Astrocytomas, Glioblastomas, Oligodendrogliomas, and Meningiomas by Gondáš, Eduard, Kráľová Trančíková, Alžbeta, Dibdiaková, Katarina, Galanda, Tomáš, Hatok, Jozef, Račay, Peter, Dobrota, Dušan, Murín, Radovan

“…Pyruvate carboxylase (PC) is an enzyme catalyzing the carboxylation of pyruvate to oxaloacetate. The enzymatic generation of oxaloacetate, an intermediate of…”
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Anti-astmatic effect of ROCK inhibitor, GSK429286 A, in experimentally induced allergic airway inflammation by Gondáš, Eduard, Mažerik, Jozef, Dohál, Matúš, Bálentová, Soňa, Pokusa, Michal, Vargová, Daniela, Smieško, Lukáš, Šutovská, Martina, Jošková, Marta, Fraňová, Soňa

“…Allergic asthma is a chronic inflammatory disease characterized by airway hyperresponsiveness, inflammation and remodeling. ROCK inhibitors have now been shown…”
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Expression of 3-Methylcrotonyl-CoA Carboxylase in Brain Tumors and Capability to Catabolize Leucine by Human Neural Cancer Cells by Gondáš, Eduard, Kráľová Trančíková, Alžbeta, Baranovičová, Eva, Šofranko, Jakub, Hatok, Jozef, Kowtharapu, Bhavani S, Galanda, Tomáš, Dobrota, Dušan, Kubatka, Peter, Busselberg, Dietrich, Murín, Radovan

“…Leucine is an essential, ketogenic amino acid with proteinogenic, metabolic, and signaling roles. It is readily imported from the bloodstream into the brain…”
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Expression of pyruvate carboxylase in cultured human astrocytoma, glioblastoma and neuroblastoma cells by Gondáš, Eduard, Kráľová Trančíková, Alžbeta, Majerčíková, Zuzana, Pokusa, Michal, Baranovičová, Eva, Bystrický, Peter, Dobrota, Dušan, Murín, Radovan

“…Pyruvate carboxylase (PC) is an enzyme catalyzing the conversion of pyruvate to oxaloacetate, which possesses anaplerotic role in cellular metabolism. The…”
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The ubiquitous expression of pyruvate carboxylase among human prostate tumors by Gondas, Eduard, Hives, Mark, Kliment, Jan, Kmetova Sivonova, Monika, Dobrota, Dusan, Murin, Radovan

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The Plasma Levels of 3-Hydroxybutyrate, Dityrosine, and Other Markers of Oxidative Stress and Energy Metabolism in Major Depressive Disorder by Krivosova, Michaela, Gondas, Eduard, Murin, Radovan, Dohal, Matus, Ondrejka, Igor, Tonhajzerova, Ingrid, Hutka, Peter, Ferencova, Nikola, Visnovcova, Zuzana, Hrtanek, Igor, Mokry, Juraj

“…Major depressive disorder (MDD) is a serious mental disease with a pathophysiology that is not yet fully clarified. An increasing number of studies show an…”
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Resistance patterns and transmission of mono- and polyresistant TB: clinical impact of WGS by Dohál, Matúš, Dvořáková, Věra, Šperková, Miluše, Pinková, Martina, Spitaleri, Andrea, Rasmussen, Erik Michael, Škereňová, Mária, Krivošová, Michaela, Gondáš, Eduard, Porvazník, Igor, Solovič, Ivan, Cirillo, Daniela Maria, Mokrý, Juraj

“…Abstract Objectives Rapidly diagnosing drug-resistant TB is crucial for improving treatment and transmission control. WGS is becoming increasingly accessible…”
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Exploring cytokine dynamics in tuberculosis: A comparative analysis of patients and controls with insights from three-week antituberculosis intervention by Krivosová, Michaela, Dohál, Matús, Mäsiarová, Simona, Prso, Kristián, Gondás, Eduard, Murín, Radovan, Franová, Sona, Porvazník, Igor, Solovic, Ivan, Mokrý, Juraj

“…Despite developing new diagnostics, drugs, and vaccines, treating tuberculosis (TB) remains challenging. Monitoring inflammatory markers can contribute to more…”
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The presence of pyruvate carboxylase in the human brain and its role in the survival of cultured human astrocytes by Gondáš, E, Kráľová Trančíková, A, Šofranko, J, Majerová, P, Lučanský, V, Dohál, M, Kováč, A, Murín, R

“…Pyruvate carboxylase (PC) is a mitochondrial, biotin-containing enzyme catalyzing the ATP-dependent synthesis of oxaloacetate from pyruvate and bicarbonate,…”
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High rate of macrolide resistance and closely genetically related Mycobacterium abscessus complex strains identified among both cystic fibrosis and non-cystic fibrosis patients within two countries by Dohál, Matúš, Dvořáková, Věra, Hromádková, Michaela, Pinková, Martina, Amlerová, Jana, Schwarz, Marek, Spitaleri, Andrea, di Marco, Federico, Hnilicová, Jarmila, Gondáš, Eduard, Rasmussen, Michael E, Porvazník, Igor, Solovič, Ivan, Cirillo, Daniela M, Mokrý, Juraj

“…is an emerging opportunistic pathogen affecting patients with chronic lung diseases, primarily cystic fibrosis (CF), or those under immunosuppression. Hence,…”
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