Search Results - "Goncharov, Tanya"

Targeted Disruption of the Mouse Caspase 8 Gene Ablates Cell Death Induction by the TNF Receptors, Fas/Apo1, and DR3 and Is Lethal Prenatally by Varfolomeev, Eugene E, Schuchmann, Marcus, Luria, Victor, Chiannilkulchai, Nuchanard, Beckmann, Jacques S, Mett, Igor L, Rebrikov, Denis, Brodianski, Vadim M, Kemper, Oliver C, Kollet, Orit, Lapidot, Tsvee, Soffer, Dror, Sobe, Tama, Avraham, Karen B, Goncharov, Tanya, Holtmann, Helmut, Lonai, Peter, Wallach, David

“…Homozygous targeted disruption of the mouse Caspase 8 ( Casp8) gene was found to be lethal in utero. The Caspase 8 null embryos exhibited impaired heart muscle…”
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Mutant p53 gain of function: repression of CD95(Fas APO-1) gene expression by tumor-associated p53 mutants by ZALCENSTEIN, Amir, STAMBOLSKY, Perry, WEISZ, Lilach, MÜLLER, Martina, WALLACH, David, GONCHAROV, Tanya M, KRAMMER, Peter H, ROTTER, Varda, OREN, Moshe

“…Tumor-associated mutant forms of p53 can exert an antiapoptotic gain of function activity, which probably confers a selective advantage upon tumor cells…”
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Involvement of MACH, a Novel MORT1/FADD-Interacting Protease, in Fas/APO-1- and TNF Receptor–Induced Cell Death by Boldin, Mark P, Goncharov, Tanya M, Goltseve, Yury V, Wallach, David

“…Fas/APO-1 and p55 tumor necrosis factor (TNF) receptor (p55-R) activate cellular mechanisms that result in cell death. Upon activation of these receptors,…”
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How are the regulators regulated? The search for mechanisms that impose specificity on induction of cell death and NF-κB activation by members of the TNF/NGF receptor family by Wallach, David, Arumugam, Thangavelu, Boldin, Mark, Cantarella, Giuseppina, Ganesh, Koluman, Goltsev, Yuri, Goncharov, Tanya, Kovalenko, Andrew, Rajput, Akhil, Varfolomeev, Eugene, Zhang, Si

“…CHAPTER SUMMARY: Signals emanating from receptors of the tumor necrosis factor/nerve growth factor (TNF/NGF) family control practically all aspects of immune…”
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Transcription-controlled gene therapy against tumor angiogenesis by Greenberger, Shoshana, Shaish, Aviv, Varda-Bloom, Nira, Levanon, Keren, Breitbart, Eyal, Goldberg, Iris, Barshack, Iris, Hodish, Israel, Yaacov, Niva, Bangio, Livnat, Goncharov, Tanya, Wallach, David, Harats, Dror

“…A major drawback of current approaches to antiangiogenic gene therapy is the lack of tissue-specific targeting. The aim of this work was to trigger endothelial…”
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A potential mechanism of "cross-talk" between the p55 tumor necrosis factor receptor and Fas/APO1: proteins binding to the death domains of the two receptors also bind to each other by Varfolomeev, E E, Boldin, M P, Goncharov, T M, Wallach, D

“…The p55 tumor necrosis factor (TNF) receptor and Fas/APO1 induce cell death via distinct regions in their intracellular domains. Three cytoplasmic proteins…”
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969. Transcription Controlled Gene Therapy Against Tumor Angiogenesis by Greenberger, Shoshana, Shaish, Aviv, Breitbart, Eyal, Hodish, Israel, Bangio, Livnat, Yaakov, Niva, Goldberg, Iris, Barshack, Iris, Wallach, David, Goncharov, Tanya, Harats, Dror

“…BackgroundAngiogenesis, the formation of new capillaries by budding from existing vessels occur in tumors and permits their growth, invasiveness and…”
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How are the regulators regulated? The search for mechanisms that impose specificity on induction of cell death and NF-kappaB activation by members of the TNF/NGF receptor family by Wallach, David, Arumugam, Thangavelu U, Boldin, Mark P, Cantarella, Giuseppina, Ganesh, Koluman A, Goltsev, Yuri, Goncharov, Tanya M, Kovalenko, Andrew V, Rajput, Akhil, Varfolomeev, Eugene E, Zhang, Si Qing

“…Signals emanating from receptors of the tumor necrosis factor/nerve growth factor (TNF/NGF) family control practically all aspects of immune defense and, as…”
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