Search Results - "Gonçalves Barbosa, Ribeiro"
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The structure of the extended E2 DNA‐binding domain of the bovine papillomavirus‐1
Published in Proteins, structure, function, and bioinformatics (01-01-2020)“…Bovine papillomavirus proteins were extensively studied as a prototype for the human papillomavirus. Here, the crystal structure of the extended E2 DNA‐binding…”
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Structural and functional characterization of a novel lipolytic enzyme from a Brazilian Cerrado soil metagenomic library
Published in Biotechnology letters (01-10-2018)“…Objective To isolate putative lipase enzymes by screening a Cerrado soil metagenomic library with novel features. Results Of 6720 clones evaluated, Clone W…”
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Crystallographic structure and substrate-binding interactions of the molybdate-binding protein of the phytopathogen Xanthomonas axonopodis pv. citri
Published in Biochimica et biophysica acta (01-02-2008)“…In Xanthomonas axonopodis pv. citri ( Xac or X. citri), the modA gene codes for a periplasmic protein (ModA) that is capable of binding molybdate and tungstate…”
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4
Homology modeling and molecular dynamics provide structural insights into tospovirus nucleoprotein
Published in BMC bioinformatics (15-12-2016)“…Tospovirus is a plant-infecting genus within the family Bunyaviridae, which also includes four animal-infecting genera: Hantavirus, Nairovirus, Phlebovirus and…”
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Interaction models between peptide substrate and Alphavirus Protease nsP2 of Chikungunya and Mayaro and implications to the mechanism of action
Published in Journal of biomolecular structure & dynamics (21-12-2023)“…The Arbovirus (Arthropod-borne virus) is a group which comprises viruses whose transmission is carried out by arthropod vectors infecting vertebrates. Some…”
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Structural and biochemical analysis reveals how ferulic acid improves catalytic efficiency of Humicola grisea xylanase
Published in Scientific reports (06-07-2022)“…Humicola grisea var. thermoidea is an aerobic and thermophilic fungus that secretes the GH11 xylanase HXYN2 in the presence of sugarcane bagasse. In this…”
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The crystal structure of a lysozyme c from housefly Musca domestica, the first structure of a digestive lysozyme
Published in Journal of structural biology (01-10-2007)“…Lysozymes from family 22 of glycoside hydrolases are usually part of the defense system against bacteria. However in ruminant artiodactyls and saprophagous…”
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Crystallographic structure of a complex between trypsin and a nonapeptide derived from a Bowman-Birk inhibitor found in Vigna unguiculata seeds
Published in Archives of biochemistry and biophysics (15-04-2019)“…Natural inhibitors of proteases have been classified into different families, among them is the Bowman-Birk Inhibitor (BBI) family. Members of BBI have two…”
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Self-homodimerization of an actinoporin by disulfide bridging reveals implications for their structure and pore formation
Published in Scientific reports (26-04-2018)“…The Trp111 to Cys mutant of sticholysin I, an actinoporin from Stichodactyla helianthus sea anemone, forms a homodimer via a disulfide bridge. The purified…”
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Crystallization and preliminary X-ray diffraction analysis of Q4DV70 from Trypanosoma cruzi, a hypothetical protein with a putative thioredoxin domain
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01-06-2009)“…Q4DV70 is annotated in the Trypanosoma cruzi CL Brener genome as a hypothetical protein with a predicted thioredoxin‐like fold, although the catalytic cysteine…”
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An improved expression and purification protocol enables the structural characterization of Mnt1, an antifungal target from Candida albicans
Published in Fungal biology and biotechnology (07-05-2024)“…Candida albicans is one of the most prevalent fungi causing infections in the world. Mnt1 is a mannosyltransferase that participates in both the cell wall…”
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Crystal structure of thioredoxin 1 from Cryptococcus neoformans at 1.8 Å resolution shows unexpected plasticity of the loop preceding the catalytic site
Published in Biochemistry and biophysics reports (01-03-2020)“…An elevated prevalence of cryptococcal infection is a tendency in low-income countries and constitutes a global public health problem due to factors such as…”
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A specific interdomain interaction preserves the structural and binding properties of the ModA protein from the phytopathogen Xanthomonas citri domain interaction and transport in ModA
Published in Archives of biochemistry and biophysics (01-11-2013)“…•K127-D59 salt-bridge is important for the structure and function of X. citri ModA.•One mutation (D59A) affects the binding properties of X. citri ModA.•The…”
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Structural and biochemical analysis reveals how ferulic acid improves catalytic efficiency of Humicolagrisea xylanase
Published in Scientific reports (06-07-2022)“…Humicola grisea var. thermoidea is an aerobic and thermophilic fungus that secretes the GH11 xylanase HXYN2 in the presence of sugarcane bagasse. In this…”
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Structural characterization of the RNA chaperone Hfq from the nitrogen-fixing bacterium Herbaspirillum seropedicae SmR1
Published in Biochimica et biophysica acta (01-02-2012)“…The RNA chaperone Hfq is a homohexamer protein identified as an E. coli host factor involved in phage Qβ replication and it is an important posttranscriptional…”
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Laboratory simulation of interplanetary ultraviolet radiation (broad spectrum) and its effects on Deinococcus radiodurans
Published in Planetary and space science (01-08-2010)“…The radiation-resistant bacterium Deinococcus radiodurans was exposed to a simulated interplanetary UV radiation at the Brazilian Synchrotron Light Laboratory…”
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Structural Characterization and Crystallization of Human TMPRSS2 Protease
Published in Biophysical journal (02-02-2018)Get full text
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Characterization of the Molecular Target KRE2 of Paraccocidioides lutzii Aiming at Development of New Antifungal Therapies
Published in Biophysical journal (02-02-2018)Get full text
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Purification, crystallization and preliminary crystallographic studies of SPCI-chymotrypsin complex at 2.8 Å resolution
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01-10-2008)“…A binary complex of the Schizolobium parahyba chymotrypsin inhibitor (SPCI) with chymotrypsin was purified by size‐exclusion chromatography and crystallized by…”
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Identification of novel Zika virus NS3 protease inhibitors with different inhibition modes by integrative experimental and computational approaches
Published in Biochimie (01-09-2023)“…Zika virus (ZIKV) infection is associated with severe neurological disorders and congenital malformation. Despite efforts to eradicate the disease, there is…”
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