Search Results - "Gonçalves, Inês O"
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Exercise mitigates mitochondrial permeability transition pore and quality control mechanisms alterations in nonalcoholic steatohepatitis
Published in Applied physiology, nutrition, and metabolism (01-03-2016)“…Mitochondrial quality control and apoptosis have been described as key components in the pathogenesis of nonalcoholic steatohepatitis (NASH); exercise is…”
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Physical exercise positively modulates nonalcoholic steatohepatitis‐related hepatic endoplasmic reticulum stress
Published in Journal of cellular biochemistry (01-10-2022)“…Obesity is a predictive factor for the development of nonalcoholic steatohepatitis (NASH). Although some of the mechanisms associated with NASH development are…”
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Effects of endurance training on autophagy and apoptotic signaling in visceral adipose tissue of prolonged high fat diet-fed rats
Published in European journal of nutrition (01-09-2018)“…Purpose Autophagy and apoptosis play critical roles in both development and tissue homeostasis in response to (patho)physiological stimuli, such as high-fat…”
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Peripherally administered melanocortins induce mice fat browning and prevent obesity
Published in International Journal of Obesity (01-05-2019)“…Background/objectives The browning of white adipose tissue (WAT) has been in the spotlight during the last years, becoming an attractive approach to combat…”
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Exercise as a therapeutic tool to prevent mitochondrial degeneration in nonalcoholic steatohepatitis
Published in European journal of clinical investigation (01-11-2013)“…Nonalcoholic fatty liver disease, encompassing hepatic steatosis, nonalcoholic steatohepatitis (NASH), fibrosis and cirrhosis, is a significant health problem…”
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Physical exercise prevents and mitigates non-alcoholic steatohepatitis-induced liver mitochondrial structural and bioenergetics impairments
Published in Mitochondrion (01-03-2014)“…Exercise is considered a non-pharmacological tool against several lifestyle disorders in which mitochondrial dysfunction is involved. The present study aimed…”
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Physical exercise mitigates high-fat diet-induced adiposopathy and related endocrine alterations in an animal model of obesity
Published in Journal of physiology and biochemistry (01-05-2018)“…The dysregulation of adipokine secretion owing to adiposopathy can contribute to the pathogenesis of obesity-related disorders. Being that exercise is an…”
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Physical exercise antagonizes clinical and anatomical features characterizing Lieber-DeCarli diet-induced obesity and related metabolic disorders
Published in Clinical nutrition (Edinburgh, Scotland) (01-04-2015)“…Summary Background & aims Lieber-DeCarli diet has been used to induce obesity and non-alcoholic steatohepatitis (NASH). As scarce anatomical and…”
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Modulation of hepatic redox status and mitochondrial metabolism by exercise: therapeutic strategy for liver diseases
Published in Mitochondrion (01-11-2013)“…Liver steatosis (non-alcoholic fatty liver disease, NAFLD) is deemed as the hepatic face of the metabolic syndrome, with both physical inactivity and…”
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Physical exercise remodels visceral adipose tissue and mitochondrial lipid metabolism in rats fed a high‐fat diet
Published in Clinical and experimental pharmacology & physiology (01-03-2017)“…Summary We aimed to investigate the effects of two physical exercise models, voluntary physical activity (VPA) and endurance training (ET) as preventive and…”
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Effects of physical exercise on myokines expression and brown adipose-like phenotype modulation in rats fed a high-fat diet
Published in Life sciences (1973) (15-11-2016)“…Exercise-stimulated myokine secretion into circulation may be related with browning in white adipose tissue (WAT), representing a positive metabolic effect on…”
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Impact of physical exercise on visceral adipose tissue fatty acid profile and inflammation in response to a high-fat diet regimen
Published in The international journal of biochemistry & cell biology (01-06-2017)“…Studies associate specific fatty-acids (FA) with the pathophysiology of inflammation. We aimed to analyze the impact of exercise on adipose tissue FA profile…”
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Acute exercise protects against calcium-induced cardiac mitochondrial permeability transition pore opening in doxorubicin-treated rats
Published in Clinical science (1979) (01-01-2011)“…The use of DOX (doxorubicin), an antibiotic used in oncological treatments, is limited by a dose-related cardiotoxicity against which acute exercise is…”
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Exercise alters liver mitochondria phospholipidomic profile and mitochondrial activity in non-alcoholic steatohepatitis
Published in The international journal of biochemistry & cell biology (01-09-2014)“…Mitochondrial membrane lipid composition is a critical factor in non-alcoholic steatohepatitis (NASH). Exercise is the most prescribed therapeutic strategy…”
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Endurance Training and Chronic Intermittent Hypobaric-Hypoxia Modulate Liver Mitochondrial Bioenergetics. Role Against Salicylate-Induced Mitochondrial Dysfunction
Published in Medicine and science in sports and exercise (01-05-2012)“…PURPOSE: To analyze the effects of ET and CIHH on LM bioenergetics under basal conditions and with salicylate. METHODS: Twenty-eight young-adult male rats were…”
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