Search Results - "Gonçalves, Cinara L."

The many faces of microbiota-gut-brain axis in autism spectrum disorder by Gonçalves, Cinara L, Doifode, Tejaswini, Rezende, Victoria L, Costa, Maiara A, Rhoads, J Marc, Soutullo, Cesar A

“…The gut-brain axis is gaining more attention in neurodevelopmental disorders, especially autism spectrum disorder (ASD). Many factors can influence microbiota…”
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Inhibition of mitochondrial respiratory chain in brain of rats subjected to an experimental model of depression by Rezin, Gislaine T., Cardoso, Mariane R., Gonçalves, Cinara L., Scaini, Giselli, Fraga, Daiane B., Riegel, Rafael E., Comim, Clarissa M., Quevedo, João, Streck, Emilio L.

“…Depressive disorders, including major depression, are serious and disabling. However, the exact pathophysiology of depression is not clearly understood. Life…”
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Mitochondria and the central nervous system: searching for a pathophysiological basis of psychiatric disorders by Streck, Emilio L, Gonçalves, Cinara L, Furlanetto, Camila B, Scaini, Giselli, Dal-Pizzol, Felipe, Quevedo, João

“…Mitochondrial dysfunction has been postulated to participate in the development of many neuropsychiatric disorders, but there is no consensus as to its role…”
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Sodium Butyrate, a Histone Deacetylase Inhibitor, Reverses Behavioral and Mitochondrial Alterations in Animal Models of Depression Induced by Early- or Late-life Stress by Valvassori, Samira S, Resende, Wilson R, Budni, Josiane, Dal-Pont, Gustavo C, Bavaresco, Daniela V, Réus, Gislaine Z, Carvalho, André F, Gonçalves, Cinara L, Furlanetto, Camila B, Streck, Emilio L, Quevedo, João

“…The aim of the present study was to evaluate the effects of sodium butyrate on depressive-like behavior and mitochondrial alteration parameters in animal…”
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Acute Carnosine Administration Increases Respiratory Chain Complexes and Citric Acid Cycle Enzyme Activities in Cerebral Cortex of Young Rats by Macedo, Levy W., Cararo, José H., Maravai, Soliany G., Gonçalves, Cinara L., Oliveira, Giovanna M. T., Kist, Luiza W., Guerra Martinez, Camila, Kurtenbach, Eleonora, Bogo, Maurício R., Hipkiss, Alan R., Streck, Emilio L., Schuck, Patrícia F., Ferreira, Gustavo C.

“…Carnosine (β-alanyl- l -histidine) is an imidazole dipeptide synthesized in excitable tissues of many animals, whose biochemical properties include carbonyl…”
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Effects of tamoxifen on tricarboxylic acid cycle enzymes in the brain of rats submitted to an animal model of mania induced by amphetamine by Valvassori, Samira S, Bavaresco, Daniela V, Budni, Josiane, Bobsin, Tamara S, Gonçalves, Cinara L, de Freitas, Karolina V, Streck, Emilio L, Quevedo, João

“…Abstract The neurobiological basis of bipolar disorder (BD) remains unknown; nevertheless, mitochondrial dysfunction has been identified in this disorder…”
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Fenproporex Increases Locomotor Activity and Alters Energy Metabolism, and Mood Stabilizers Reverse These Changes: a Proposal for a New Animal Model of Mania by Rezin, Gislaine T., Furlanetto, Camila B., Scaini, Giselli, Valvassori, Samira S., Gonçalves, Cinara L., Ferreira, Gabriela K., Jeremias, Isabela C., Resende, Wilson R., Cardoso, Mariane R., Varela, Roger B., Quevedo, João, Streck, Emilio L.

“…Fenproporex (Fen) is converted in vivo into amphetamine, which is used to induce mania-like behaviors in animals. In the present study, we intend to present a…”
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l-Tyrosine administration increases acetylcholinesterase activity in rats by Ferreira, Gabriela K., Carvalho-Silva, Milena, Gonçalves, Cinara L., Vieira, Júlia S., Scaini, Giselli, Ghedim, Fernando V., Deroza, Pedro F., Zugno, Alexandra I., Pereira, Talita C.B., Oliveira, Giovanna M.T., Kist, Luiza W., Bogo, Maurício R., Schuck, Patrícia F., Ferreira, Gustavo C., Streck, Emilio L.

“…► Chronic administration of l-tyrosine increased AChE activity. ► Acute administration in 10 and 30-day-old rats increased AChE activity. ► Acute…”
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Effects of Mood Stabilizers on Brain Energy Metabolism in Mice Submitted to an Animal Model of Mania Induced by Paradoxical Sleep Deprivation by Streck, Emilio L., Scaini, Giselli, Jeremias, Gabriela C., Rezin, Gislaine T., Gonçalves, Cinara L., Ferreira, Gabriela K., Réus, Gislaine Z., Resende, Wilson R., Valvassori, Samira S., Kapczinski, Flávio, Andersen, Mônica L., Quevedo, João

“…There is a body of evidence suggesting that mitochondrial dysfunction is involved in bipolar disorder (BD) pathogenesis. Studies suggest that abnormalities in…”
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An Evaluation of the Effects of Acute and Chronic l-Tyrosine Administration on BDNF Levels and bdnf mRNA Expression in the Rat Brain by Ferreira, Gabriela K., Scaini, Giselli, Jeremias, Isabela C., Carvalho-Silva, Milena, Gonçalves, Cinara L., Pereira, Talita C. B., Oliveira, Giovanna M. T., Kist, Luiza W., Bogo, Maurício R., Schuck, Patrícia F., Ferreira, Gustavo C., Streck, Emilio L.

“…Tyrosinemia type II, which is also known as Richner–Hanhart syndrome, is an inborn error of metabolism that is due to a block in the transamination reaction…”
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Skeletal Muscle Electron Transport Chain Dysfunction After Sepsis in Rats by Peruchi, Bruno B., M.Sc, Petronilho, Fabrícia, Ph.D, Rojas, Hugo A., M.Sc, Constantino, Larissa, M.Sc, Mina, Francielle, B.Sc, Vuolo, Francieli, B.Sc, Cardoso, Mariane R., B.Sc, Gonçalves, Cinara L., B.Sc, Rezin, Gislaine T., M.Sc, Streck, Emílio L., Ph.D, Dal-Pizzol, Felipe, M.D., Ph.D

“…Background The derangement in oxygen utilization occurring during sepsis is likely to be linked to impaired mitochondrial functioning. Skeletal muscle…”
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Acute administration of ketamine reverses the inhibition of mitochondrial respiratory chain induced by chronic mild stress by Rezin, Gislaine T, Gonçalves, Cinara L, Daufenbach, Juliana F, Fraga, Daiane B, Santos, Patricia M, Ferreira, Gabriela K, Hermani, Fernanda V, Comim, Clarissa M, Quevedo, João, Streck, Emilio L

“…Abstract Modulation and dysfunction of the glutamatergic system seems to be involved in depression. Recently a renewed interest in the glutamatergic system as…”
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Effects of N-Acetylcysteine/Deferoxamine, Taurine and RC-3095 on Respiratory Chain Complexes and Creatine Kinase Activities in Rat Brain After Sepsis by Cassol, Omar J., Rezin, Gislaine T., Petronilho, Fabrícia C., Scaini, Giselli, Gonçalves, Cinara L., Ferreira, Gabriela K., Roesler, Rafael, Schwartsmann, Gilberto, Dal-Pizzol, Felipe, Streck, Emilio L.

“…The pathogenesis of sepsis is characterized by an overwhelming systemic inflammatory response that can lead to multiple organ failure. Considering that we have…”
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Fluvoxamine alters the activity of energy metabolism enzymes in the brain by Ferreira, Gabriela K, Cardoso, Mariane R, Jeremias, Isabela C, Gonçalves, Cinara L, Freitas, Karolina V, Antonini, Rafaela, Scaini, Giselli, Rezin, Gislaine T, Quevedo, João, Streck, Emilio L

“…Several studies support the hypothesis that metabolism impairment is involved in the pathophysiology of depression and that some antidepressants act by…”
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Inhibition of mitochondrial respiratory chain in the brain of rats after hepatic failure induced by acetaminophen by Panatto, Jordana P, Jeremias, Isabela C, Ferreira, Gabriela K, Ramos, Ândrea C, Rochi, Natalia, Gonçalves, Cinara L, Daufenbach, Juliana F, Jeremias, Gabriela C, Carvalho-Silva, Milena, Rezin, Gislaine T, Scaini, Giselli, Streck, Emilio L

“…Hepatic encephalopathy is an important cause of morbidity and mortality in patients with severe hepatic failure. This disease is clinically characterized by a…”
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Effects of acute and chronic administration of fenproporex on DNA damage parameters in young and adult rats by Gonçalves, Cinara L., Rezin, Gislaine T., Ferreira, Gabriela K., Jeremias, Isabela C., Cardoso, Mariane R., Valvassori, Samira S., Munhoz, Bruna J. P., Borges, Gabriela D., Bristot, Bruno N., Leffa, Daniela D., Andrade, Vanessa M., Quevedo, João, Streck, Emilio L.

“…Obesity is a chronic and multifactorial disease, whose prevalence is increasing in many countries. Pharmaceutical strategies for the treatment of obesity…”
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Evaluation of Na+, K+-ATPase activity in the brain of young rats after acute administration of fenproporex by Rezin, Gislaine T, Scaini, Giselli, Gonçalves, Cinara L, Ferreira, Gabriela K, Cardoso, Mariane R, Ferreira, Andréa G K, Cunha, Maira J, Schmitz, Felipe, Varela, Roger B, Quevedo, João, Wyse, Angela T S, Streck, Emilio L

“…Fenproporex is an amphetamine-based anorectic which is rapidly converted into amphetamine in vivo. Na+, K+-ATPase is a membrane-bound enzyme necessary to…”
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Inhibition of acetylcholinesterase activity in brain and behavioral analysis in adult rats after chronic administration of fenproporex by Rezin, Gislaine T., Scaini, Giselli, Ferreira, Gabriela K., Cardoso, Mariane R., Gonçalves, Cinara L., Constantino, Larissa S., Deroza, Pedro F., Ghedim, Fernando V., Valvassori, Samira S., Resende, Wilson R., Quevedo, João, Zugno, Alexandra I., Streck, Emilio L.

“…Fenproporex is an amphetamine-based anorectic and it is rapidly converted in vivo into amphetamine. It elevates the levels of extracellular dopamine in the…”
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Administration of Harmine and Imipramine Alters Creatine Kinase and Mitochondrial Respiratory Chain Activities in the Rat Brain by Réus, Gislaine Z, Stringari, Roberto B, Gonçalves, Cinara L, Scaini, Giselli, Carvalho-Silva, Milena, Jeremias, Gabriela C, Jeremias, Isabela C, Ferreira, Gabriela K, Streck, Emílio L, Hallak, Jaime E, Zuardi, Antônio W, Crippa, José A, Quevedo, João

“…The present study evaluated mitochondrial respiratory chain and creatine kinase activities after administration of harmine (5, 10, and 15 mg/kg) and imipramine…”
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Pre- and Post-Synaptic protein in the major depressive Disorder: From neurobiology to therapeutic targets by Silva, Ritele H., Pedro, Lucas C., Manosso, Luana M., Gonçalves, Cinara L., Réus, Gislaine Z.

“…•Understanding MDD and its pathophysiology aids in treatment improvement.•Synaptic plasticity is crucial in MDD and drug response, involving key…”
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