Search Results - "Gomori, J Moshe"

Biochemical phosphates observed using hyperpolarized 31P in physiological aqueous solutions by Nardi-Schreiber, Atara, Gamliel, Ayelet, Harris, Talia, Sapir, Gal, Sosna, Jacob, Gomori, J. Moshe, Katz-Brull, Rachel

“…The dissolution-dynamic nuclear polarization technology had previously enabled nuclear magnetic resonance detection of various nuclei in a hyperpolarized…”
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Curbing action potential generation or ATP-synthase leads to a decrease in in-cell pyruvate dehydrogenase activity in rat cerebrum slices by Grieb, Benjamin, Uppala, Sivaranjan, Sapir, Gal, Shaul, David, Gomori, J. Moshe, Katz-Brull, Rachel

“…Direct and real-time monitoring of cerebral metabolism exploiting the drastic increase in sensitivity of hyperpolarized 13 C-labeled metabolites holds the…”
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In-cell determination of Lactate Dehydrogenase Activity in a Luminal Breast Cancer Model ⁻ ex vivo Investigation of Excised Xenograft Tumor Slices Using dDNP Hyperpolarized [1- 13 C]pyruvate by Adler-Levy, Yael, Nardi-Schreiber, Atara, Harris, Talia, Shaul, David, Uppala, Sivaranjan, Sapir, Gal, Lev-Cohain, Naama, Sosna, Jacob, Goldberg, Shraga Nahum, Gomori, J Moshe, Katz-Brull, Rachel

“…[1- C]pyruvate, the most widely used compound in dissolution-dynamic nuclear polarization (dDNP) magnetic resonance (MR), enables the visualization of lactate…”
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Observation of glucose-6-phosphate anomeric exchange in real-time using dDNP hyperpolarised NMR by Uppala, Sivaranjan, Gamliel, Ayelet, Sapir, Gal, Sosna, Jacob, Gomori, J. Moshe, Katz-Brull, Rachel

“…A hyperpolarised-NMR acquisition approach that is sensitive to the process of glucose-6-phosphate anomerization is presented. Using selective depolarisation of…”
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Adult polyglucosan body disease: Natural History and Key Magnetic Resonance Imaging Findings by Mochel, Fanny, Schiffmann, Raphael, Steenweg, Marjan E., Akman, Hasan O., Wallace, Mary, Sedel, Frédéric, Laforêt, Pascal, Levy, Richard, Powers, J. Michael, Demeret, Sophie, Maisonobe, Thierry, Froissart, Roseline, Da Nobrega, Bruno Barcelos, Fogel, Brent L., Natowicz, Marvin R., Lubetzki, Catherine, Durr, Alexandra, Brice, Alexis, Rosenmann, Hanna, Barash, Varda, Kakhlon, Or, Gomori, J. Moshe, van der Knaap, Marjo S., Lossos, Alexander

“…Objective: Adult polyglucosan body disease (APBD) is an autosomal recessive leukodystrophy characterized by neurogenic bladder, progressive spastic gait, and…”
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[13C6,D8]2-deoxyglucose phosphorylation by hexokinase shows selectivity for the β-anomer by Sapir, Gal, Harris, Talia, Uppala, Sivaranjan, Nardi-Schreiber, Atara, Sosna, Jacob, Gomori, J. Moshe, Katz-Brull, Rachel

“…A non-radioactive 2-deoxyglucose (2DG) analog has been developed here for hyperpolarized magnetic resonance investigations. The analog, [ 13 C 6 ,D 8 ]2DG,…”
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Accumulation of 3‐aminopropylphosphonate in the ex vivo brain observed by phosphorus‐31 nuclear magnetic resonance by Shaul, David, Grieb, Benjamin, Lev‐Cohain, Naama, Sosna, Jacob, Gomori, J. Moshe, Katz‐Brull, Rachel

“…3‐aminopropylphosphonate (3‐APP) is known for its use as an exogenous indicator of extracellular volume and pH in phosphorus‐31 nuclear magnetic resonance (31P…”
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Reversible functional connectivity disturbances during transient global amnesia by Peer, Michael, Nitzan, Mor, Goldberg, Ilan, Katz, Judith, Gomori, J. Moshe, Ben-Hur, Tamir, Arzy, Shahar

“…Objective Transient global amnesia (TGA), an abrupt occurrence of severe anterograde episodic amnesia accompanied by repetitive questioning, has been known for…”
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Real-time ex-vivo measurement of brain metabolism using hyperpolarized [1-13C]pyruvate by Harris, Talia, Azar, Assad, Sapir, Gal, Gamliel, Ayelet, Nardi-Schreiber, Atara, Sosna, Jacob, Gomori, J. Moshe, Katz-Brull, Rachel

“…The ability to directly monitor in vivo brain metabolism in real time in a matter of seconds using the dissolution dynamic nuclear polarization technology…”
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Correlation between lactate dehydrogenase/pyruvate dehydrogenase activities ratio and tissue pH in the perfused mouse heart: A potential noninvasive indicator of cardiac pH provided by hyperpolarized magnetic resonance by Shaul, David, Azar, Assad, Sapir, Gal, Uppala, Sivaranjan, Nardi‐Schreiber, Atara, Gamliel, Ayelet, Sosna, Jacob, Gomori, J. Moshe, Katz‐Brull, Rachel

“…Cardiovascular diseases account for more than 30% of all deaths worldwide and many could be ameliorated with early diagnosis. Current cardiac imaging…”
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Author Correction: Biochemical phosphates observed using hyperpolarized 31P in physiological aqueous solutions by Nardi-Schreiber, Atara, Gamliel, Ayelet, Harris, Talia, Sapir, Gal, Sosna, Jacob, Gomori, J. Moshe, Katz-Brull, Rachel

“…The original version of the Supplementary Information associated with this Article contained an error in Supplementary Figure 2 and Supplementary Figure 5 in…”
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Hyperpolarized product selective saturating‐excitations for determination of changes in metabolic reaction rates in real‐time by Harris, Talia, Uppala, Sivaranjan, Lev‐Cohain, Naama, Adler‐Levy, Yael, Shaul, David, Nardi‐Schreiber, Atara, Sapir, Gal, Azar, Assad, Gamliel, Ayelet, Sosna, Jacob, Gomori, J. Moshe, Katz‐Brull, Rachel

“…Investigation of hyperpolarized substrate metabolism has been showing utility in real‐time determination of in‐cell and in vivo enzymatic activities…”
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Real‐time ALT and LDH activities determined in viable precision‐cut mouse liver slices using hyperpolarized [1‐13C]pyruvate—Implications for studies on biopsied liver tissues by Lev‐Cohain, Naama, Sapir, Gal, Harris, Talia, Azar, Assad, Gamliel, Ayelet, Nardi‐Schreiber, Atara, Uppala, Sivaranjan, Sosna, Jacob, Gomori, J. Moshe, Katz‐Brull, Rachel

“…Precision‐cut liver slices (PCLS) are widely used in liver research as they provide a liver model with all liver cell types in their natural architecture. The…”
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Hyperpolarized [15N]nitrate as a potential long lived hyperpolarized contrast agent for MRI by Gamliel, Ayelet, Uppala, Sivaranjan, Sapir, Gal, Harris, Talia, Nardi-Schreiber, Atara, Shaul, David, Sosna, Jacob, Gomori, J. Moshe, Katz-Brull, Rachel

“…[Display omitted] •Dissolution-DNP hyperpolarized [15N]nitrate was observed at 1% polarization and showed a T1 of about 170 s in solution at 10–20 °C.•The T1…”
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Frequent misdiagnosis of adult polyglucosan body disease by Hellmann, Mark A., Kakhlon, Or, Landau, Ezekiel H., Sadeh, Menachem, Giladi, Nir, Schlesinger, Ilana, Kidron, Daphne, Abramsky, Oded, Reches, Avinoam, Argov, Zohar, Rabey, Jose M., Chapman, Joab, Rosenmann, Hanna, Gal, Aya, Moshe Gomori, J., Meiner, Vardiella, Lossos, Alexander

“…Adult polyglucosan body disease (APBD) is a rare glycogenosis manifesting progressive spastic paraparesis, sensorimotor polyneuropathy and neurogenic bladder…”
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Emergent revascularization of acute tandem vertebrobasilar occlusions: Endovascular approaches and technical considerations—Confirming the role of vertebral artery ostium stenosis as a cause of vertebrobasilar stroke by Cohen, José E, Leker, Ronen R, Gomori, J. Moshe, Eichel, Roni, Rajz, Gustavo, Moscovici, Samuel, Itshayek, Eyal

“…Highlights • Tandem vertebrobasilar occlusions were safely managed with endovascular techniques. • Basilar artery access was via the contralateral (clean-road)…”
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In vitro visualization of betaine aldehyde synthesis and oxidation using hyperpolarized magnetic resonance spectroscopy by Allouche-Arnon, Hyla, Gamliel, Ayelet, Sosna, Jacob, Gomori, J Moshe, Katz-Brull, Rachel

“…Real-time monitoring of betaine aldehyde metabolism at high temporal resolution was accomplished using a hyperpolarized choline analog and (13)C-NMR. This…”
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LDH and PDH Activities in the Ischemic Brain and the Effect of Reperfusion-An Ex Vivo MR Study in Rat Brain Slices Using Hyperpolarized [1- 13 C]Pyruvate by Sapir, Gal, Shaul, David, Lev-Cohain, Naama, Sosna, Jacob, Gomori, Moshe J, Katz-Brull, Rachel

“…Ischemic stroke is a leading cause for neurologic disability worldwide, for which reperfusion is the only available treatment. Neuroimaging in stroke guides…”
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Stent and flow diverter assisted treatment of acutely ruptured brain aneurysms by Cohen, José E, Gomori, J Moshe, Leker, Ronen R, Spektor, Sergey, Abu El Hassan, Hosni, Itshayek, Eyal

“…We present our experience with stent techniques in the management of acutely ruptured aneurysms, focusing on aneurysm occlusion rates, intraprocedural…”
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Quantification of rate constants for successive enzymatic reactions with DNP hyperpolarized MR by Allouche-Arnon, Hyla, Hovav, Yonatan, Friesen-Waldner, Lanette, Sosna, Jacob, Moshe Gomori, J., Vega, Shimon, Katz-Brull, Rachel

“…A kinetic model is provided to obtain reaction rate constants in successive enzymatic reactions that are monitored using NMR spectroscopy and hyperpolarized…”
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