Search Results - "Gomez, Elisa"
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Megakaryocyte production is sustained by direct differentiation from erythromyeloid progenitors in the yolk sac until midgestation
Published in Immunity (Cambridge, Mass.) (13-07-2021)“…The extra-embryonic yolk sac contains the first definitive multipotent hematopoietic cells, denominated erythromyeloid progenitors. They originate in situ…”
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Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice
Published in Nature immunology (01-10-2014)“…Many tissue-resident macrophages are derived from embryonic precursors. Mowat and colleagues show that embryonic precursor cells seed gut tissues but at…”
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The development and maintenance of resident macrophages
Published in Nature immunology (01-01-2016)“…Gomez Perdiguero and Geissmann discuss the origin of tissue macrophages as a layered system composed of resident macrophages originating mostly from yolk-sac…”
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Development and homeostasis of "resident" myeloid cells: The case of the microglia
Published in Glia (01-01-2013)“…Microglia, macrophages of the central nervous system, play an important role in brain homeostasis. Their origin has been unclear. Recent fate‐mapping…”
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Myostatin antibody (LY2495655) in older weak fallers: a proof-of-concept, randomised, phase 2 trial
Published in The lancet. Diabetes & endocrinology (01-12-2015)“…Summary Background Myostatin inhibits skeletal muscle growth. The humanised monoclonal antibody LY2495655 (LY) binds and neutralises myostatin. We aimed to…”
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Specification of tissue-resident macrophages during organogenesis
Published in Science (American Association for the Advancement of Science) (09-09-2016)“…Tissue-resident macrophages support embryonic development and tissue homeostasis and repair. The mechanisms that control their differentiation remain unclear…”
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Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways
Published in Nature neuroscience (01-03-2013)“…This study describes the transcriptional programming of yolk sac–derived microglia specification in the brain, in which c-kit–positive erythromyeloid cells are…”
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A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells
Published in Science (American Association for the Advancement of Science) (06-04-2012)“…Macrophages and dendritic cells (DCs) are key components of cellular immunity and are thought to originate and renew from hematopoietic stem cells (HSCs)…”
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Ontogeny of arterial macrophages defines their functions in homeostasis and inflammation
Published in Nature communications (11-09-2020)“…Arterial macrophages have different developmental origins, but the association of macrophage ontogeny with their phenotypes and functions in adulthood is still…”
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The Origin of Tissue-Resident Macrophages: When an Erythro-myeloid Progenitor Is an Erythro-myeloid Progenitor
Published in Immunity (Cambridge, Mass.) (15-12-2015)“…[...]E7.5 yolk sac cells, including those that give rise to tissue-resident macrophages, can be genetically marked by Tie2-MerCreMer but not by Kit-MeriCreMer,…”
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Lymphomyeloid Contribution of an Immune-Restricted Progenitor Emerging Prior to Definitive Hematopoietic Stem Cells
Published in Cell stem cell (07-11-2013)“…In jawed vertebrates, development of an adaptive immune-system is essential for protection of the born organism against otherwise life-threatening pathogens…”
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Identifying common treatments from Electronic Health Records with missing information. An application to breast cancer
Published in PloS one (29-12-2020)“…The aim of this paper is to analyze the sequence of actions in the health system associated with a particular disease. In order to do that, using Electronic…”
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Schizosaccharomyces versatilis represents a distinct evolutionary lineage of fission yeast
Published in Yeast (Chichester, England) (01-03-2024)“…The fission yeast species Schizosaccharomyces japonicus is currently divided into two varieties—S. japonicus var. japonicus and S. japonicus var. versatilis…”
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Chemical composition and antifungal properties of commercial essential oils against the maize phytopathogenic fungus Fusarium verticillioides
Published in Revista argentina de microbiología (01-10-2021)“…The aim of the present study was to analyze the chemical composition of Curcuma longa, Pimenta dioica, Rosmarinus officinalis, and Syzygium aromaticum…”
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Double-blind, randomized, placebo-controlled trial of allergen-specific immunotherapy with the major allergen Alt a 1
Published in Journal of allergy and clinical immunology (01-07-2019)“…There have been few studies conducted on the efficacy and safety of specific immunotherapy with allergen extracts of fungi compared with other allergen…”
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Achievement of glycaemic targets with weight loss and without hypoglycaemia in type 2 diabetes with the once‐weekly glucose‐dependent insulinotropic polypeptide and glucagon‐like peptide‐1 receptor agonist tirzepatide: A post hoc analysis of the SURPASS‐1 to ‐5 studies
Published in Diabetes, obesity & metabolism (01-04-2023)“…Aim To assess composite endpoints combining glycaemic control (HbA1c < 7.0%, ≤ 6.5% or < 5.7%) with weight loss (≥ 5%, ≥ 10% or ≥ 15%) and without…”
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Shape memory cycle conditions impact human bone marrow stromal cell binding to RGD- and YIGSR-conjugated poly (glycerol dodecanedioate)
Published in Acta biomaterialia (15-09-2024)“…Bioresorbable shape memory polymers (SMP) are an emerging class of polymers that can help address several challenges associated with minimally invasive surgery…”
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Removal of Different Dye Solutions: A Comparison Study Using a Polyamide NF Membrane
Published in Membranes (Basel) (10-12-2020)“…The removal of organic dyes in aquatic media is, nowadays, a very pressing environmental problem. These dyes usually come from industries, such as textiles,…”
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Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors
Published in Nature (London) (26-02-2015)“…To determine the origin of adult tissue-resident macrophages, a mouse lineage tracing study has revealed that these cells derive from erythro-myeloid…”
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Identifying the infiltrators
Published in Science (23-05-2014)“…Molecular characterization of macrophages reveals distinct types during tumorigenesis [Also see Report by Franklin et al. ] The mammalian immune system both…”
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