Search Results - "Gomes de Souza, Diogo Onofre"

The Brazilian-Portuguese version of the Sleep Hygiene Index (SHI): validity, reliability and association with depressive symptoms and sleep-related outcomes by Tonon, André Comiran, Amando, Guilherme Rodriguez, Carissimi, Alicia, Freitas, Juliana Jury, Xavier, Nicóli Bertuol, Caumo, Guilherme Hidalgo, Silva, Luka Gawlinski, de Souza, Diogo Onofre Gomes, Hidalgo, Maria Paz

“…Objective: To translate the Sleep Hygiene Index (SHI) to Brazilian Portuguese, to describe its psychometric properties and to show its association with sleep…”
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Neuroprotective Effects of Guanosine Administration on In Vivo Cortical Focal Ischemia in Female and Male Wistar Rats by Teixeira, Luciele Varaschini, Almeida, Roberto Farina, Rohden, Francieli, Martins, Leo Anderson Meira, Spritzer, Poli Mara, de Souza, Diogo Onofre Gomes

“…Guanosine (GUO) has neuroprotective effects in experimental models of brain diseases involving glutamatergic excitotoxicity in male animals; however, its…”
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A randomized, phase 2 clinical trial of lithium carbonate in Machado-Joseph disease by Saute, Jonas Alex Morales, de Castilhos, Raphael Machado, Monte, Thais Lampert, Schumacher-Schuh, Artur Francisco, Donis, Karina Carvalho, D'Ávila, Rui, Souza, Gabriele Nunes, Russo, Aline Dutra, Furtado, Gabriel Vasata, Gheno, Tailise Conte, de Souza, Diogo Onofre Gomes, Portela, Luis Valmor Cruz, Saraiva-Pereira, Maria-Luiza, Camey, Suzi Alvez, Torman, Vanessa Bielefeld Leotti, de Mello Rieder, Carlos Roberto, Jardim, Laura Bannach

“…ABSTRACT Background Because lithium exerts neuroprotective effects in preclinical models of polyglutamine disorders, our objective was to assess the safety and…”
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Guanosine protects against Ca2+-induced mitochondrial dysfunction in rats by Courtes, Aline Alves, de Carvalho, Nelson Rodrigues, Gonçalves, Débora Farina, Hartmann, Diane Duarte, da Rosa, Pamela Carvalho, Dobrachinski, Fernando, Franco, Jeferson Luis, de Souza, Diogo Onofre Gomes, Soares, Félix Alexandre Antunes

“…•Guanosine prevent mitochondrial dysfunction induced by calcium (Ca2+) misbalance.•Maintaining mitochondrial functionality and calcium homeostasis as one of…”
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Long-term effect of uncomplicated Plasmodium berghei ANKA malaria on memory and anxiety-like behaviour in C57BL/6 mice by de Sousa, Luciana Pereira, de Almeida, Roberto Farina, Ribeiro-Gomes, Flávia Lima, de Moura Carvalho, Leonardo José, E Souza, Tadeu Mello, de Souza, Diogo Onofre Gomes, Daniel-Ribeiro, Cláudio Tadeu

“…Cerebral malaria, the main complication of Plasmodium falciparum infection in humans, is associated with persistent neurocognitive sequels both in human…”
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Increased glutamate receptor and transporter expression in the cerebral cortex and striatum of gcdh-/- mice: possible implications for the neuropathology of glutaric acidemia type I by Lagranha, Valeska Lizzi, Matte, Ursula, de Carvalho, Talita Giacomet, Seminotti, Bianca, Pereira, Carolina Coffi, Koeller, David M, Woontner, Michael, Goodman, Stephen I, de Souza, Diogo Onofre Gomes, Wajner, Moacir

“…We determined mRNA expression of the ionotropic glutamate receptors NMDA (NR1, NR2A and NR2B subunits), AMPA (GluR2 subunit) and kainate (GluR6 subunit), as…”
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Disturbance of the glutamatergic system by glutaric acid in striatum and cerebral cortex of glutaryl-CoA dehydrogenase-deficient knockout mice: Possible implications for the neuropathology of glutaric acidemia type I by Busanello, Estela Natacha Brandt, Fernandes, Carolina Gonçalves, Martell, Rafael Volter, Lobato, Vannessa Gonçalves Araujo, Goodman, Stephen, Woontner, Michael, de Souza, Diogo Onofre Gomes, Wajner, Moacir

“…Abstract The role of excitotoxicity on the neuropathology of glutaric acidemia type I (GA I) is still under debate. Therefore, in the present work, we…”
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Changes in Brain 14-3-3 Proteins in Response to Insulin Resistance Induced by a High Palatable Diet by Bock, Hugo, Zimmer, Aline Rigon, Zimmer, Eduardo Rigon, de Souza, Diogo Onofre Gomes, Portela, Luis Valmor Cruz, Saraiva-Pereira, Maria Luiza

“…The 14-3-3 protein family takes part in a wide range of cellular processes and is expressed in all eukaryotic organisms. In mammals, seven isoforms (β, ε, η,…”
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High-Glucose and S100B Stimulate Glutamate Uptake in C6 Glioma Cells by Tramontina, Ana Carolina, Nardin, Patrícia, Quincozes-Santos, André, Tortorelli, Lucas, Wartchow, Krista Minéia, Andreazza, Ana Cristina, Braganhol, Elizandra, de Souza, Diogo Onofre Gomes, Gonçalves, Carlos-Alberto

“…Diabetes mellitus is a disease associated with several changes in the central nervous system, including oxidative stress and abnormal glutamatergic…”
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Cellular Senescence Induced by Prolonged Subculture Adversely Affects Glutamate Uptake in C6 Lineage by Pereira, Mery Stéfani Leivas, Zenki, Kamila, Cavalheiro, Marcela Mendonça, Thomé, Chairini Cássia, Filippi-Chiela, Eduardo Cremonese, Lenz, Guido, de Souza, Diogo Onofre Gomes, de Oliveira, Diogo Losch

“…Several researchers have recently used C6 cells to evaluate functional properties of high-affinity glutamate transporters. However, it has been demonstrated…”
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Pristanic Acid Provokes Lipid, Protein, and DNA Oxidative Damage and Reduces the Antioxidant Defenses in Cerebellum of Young Rats by Busanello, Estela Natacha Brandt, Lobato, Vannessa Gonçalves Araujo, Zanatta, Ângela, Borges, Clarissa Günther, Tonin, Anelise Miotti, Viegas, Carolina Maso, Manfredini, Vanusa, Ribeiro, César Augusto João, Vargas, Carmen Regla, de Souza, Diogo Onofre Gomes, Wajner, Moacir

“…Zellweger syndrome (ZS) and some peroxisomal diseases are severe inherited disorders mainly characterized by neurological symptoms and cerebellum…”
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No major clinical impact of Val66Met BDNF gene polymorphism on temporal lobe epilepsy by Bragatti, José Augusto, Schenkel, Laila Cigana, Torres, Carolina Machado, Manfro, Gisele Gus, Blaya, Carolina, Souza, Ana Claudia de, Souza, Diogo Onofre Gomes de, Saraiva-Pereira, Maria Luiza, Jardim, Laura Bannach, Leistner-Segal, Sandra, Bianchin, Marino Muxfeldt

“…Summary Objective To report the frequencies of Val66Met polymorphism in patients with temporal lobe epilepsy (TLE) compared to normal controls. We also…”
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Glycine disrupts myelin, glutamatergic neurotransmission, and redox homeostasis in a neonatal model for non ketotic hyperglycinemia by Parmeggiani, Belisa, Signori, Marian Flores, Cecatto, Cristiane, Frusciante, Marina Rocha, Marcuzzo, Manuela Bianchin, Souza, Débora Guerini, Ribeiro, Rafael Teixeira, Seminotti, Bianca, Gomes de Souza, Diogo Onofre, Ribeiro, César Augusto João, Wajner, Moacir, Leipnitz, Guilhian

“…Non ketotic hyperglycinemia (NKH) is an inborn error of glycine metabolism caused by mutations in the genes encoding glycine cleavage system proteins. Classic…”
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Experimental evidence that overexpression of NR2B glutamate receptor subunit is associated with brain vacuolation in adult glutaryl-CoA dehydrogenase deficient mice: A potential role for glutamatergic-induced excitotoxicity in GA I neuropathology by Rodrigues, Marília Danyelle Nunes, Seminotti, Bianca, Amaral, Alexandre Umpierrez, Leipnitz, Guilhian, Goodman, Stephen Irwin, Woontner, Michael, de Souza, Diogo Onofre Gomes, Wajner, Moacir

“…Abstract Glutaric aciduria type I (GA I) is biochemically characterized by accumulation of glutaric and 3-hydroxyglutaric acids in body fluids and tissues,…”
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Brain injury markers (S100B and NSE) in chronic cocaine dependents by Kessler, Felix Henrique Paim, Woody, George, Portela, Luís Valmor Cruz, Tort, Adriano Bretanha Lopes, De Boni, Raquel, Peuker, Ana Carolina Wolf Baldino, Genro, Vanessa, von Diemen, Lísia, de Souza, Diogo Onofre Gomes, Pechansky, Flavio

“…Studies have shown signs of brain damage caused by different mechanisms in cocaine users. The serum neuron specific enolase and S100B protein are considered…”
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Selenium Compounds Prevent Amyloid β-Peptide Neurotoxicity in Rat Primary Hippocampal Neurons by Godoi, Gabriela Lorea, de Oliveira Porciúncula, Lisiane, Schulz, Janaína Fagundes, Kaufmann, Fernanda Neutzling, da Rocha, João Batista, de Souza, Diogo Onofre Gomes, Ghisleni, Gabriele, de Almeida, Hiram Larangeira

“…Neuropathological hallmarks of Alzheimer’s disease (AD) include amyloid plaque formation, neurofibrillary tangles, neuronal and synaptic loss. This study aims…”
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α-Ketoadipic Acid and α-Aminoadipic Acid Cause Disturbance of Glutamatergic Neurotransmission and Induction of Oxidative Stress In Vitro in Brain of Adolescent Rats by da Silva, Janaína Camacho, Amaral, Alexandre Umpierrez, Cecatto, Cristiane, Wajner, Alessandro, dos Santos Godoy, Kálita, Ribeiro, Rafael Teixeira, de Mello Gonçalves, Aline, Zanatta, Ângela, da Rosa, Mateus Struecker, Loureiro, Samanta Oliveira, Vargas, Carmen Regla, Leipnitz, Guilhian, de Souza, Diogo Onofre Gomes, Wajner, Moacir

“…Tissue accumulation of α-ketoadipic (KAA) and α-aminoadipic (AAA) acids is the biochemical hallmark of α-ketoadipic aciduria. This inborn error of metabolism…”
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O uso do diário como dispositivo cartográfico na formação em Odontologia by Eliane Teixeira Leite Flores, Diogo Onofre Gomes de Souza

“…A desnaturalização de práticas de ensino tradicionais e a subjetivação do cuidado na formação conectam a Odontologia às ciências humanas e sociais ao…”
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Disruption of brain redox homeostasis in glutaryl-CoA dehydrogenase deficient mice treated with high dietary lysine supplementation by Seminotti, Bianca, Amaral, Alexandre Umpierrez, da Rosa, Mateus Struecker, Fernandes, Carolina Gonçalves, Leipnitz, Guilhian, Olivera-Bravo, Silvia, Barbeito, Luis, Ribeiro, César Augusto J., de Souza, Diogo Onofre Gomes, Woontner, Michael, Goodman, Stephen I., Koeller, David M., Wajner, Moacir

“…Deficiency of glutaryl-CoA dehydrogenase (GCDH) activity or glutaric aciduria type I (GA I) is an inherited neurometabolic disorder biochemically characterized…”
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Zika virus‐induced brain malformations in chicken embryos by Wachholz, Gabriela Elis, Varela, Ana Paula Muterle, Teixeira, Thais Fumaco, Matos, Sophia Martins Simon, Soster, Paula, Vianna, Fernanda Sales Luiz, Souza, Diogo Onofre Gomes, Roehe, Paulo Michel, Schuler‐Faccini, Lavínia, Fraga, Lucas Rosa

“…Background Zika virus (ZIKV) was confirmed to be related to microcephaly in 2016. However, there is still a need for understanding the embryonic morphological…”
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