Search Results - "Gomes Dos Santos, Ana L."

Optimization of Printing Parameters for Digital Light Processing 3D Printing of Hollow Microneedle Arrays by Mathew, Essyrose, Pitzanti, Giulia, Gomes Dos Santos, Ana L, Lamprou, Dimitrios A

“…3D printing is an emerging technology aiming towards personalized drug delivery, among many other applications. Microneedles (MN) are a viable method for…”
Get full text

Sequence-based prediction of the intrinsic solubility of peptides containing non-natural amino acids by Oeller, Marc, Kang, Ryan J. D., Bolt, Hannah L., Gomes dos Santos, Ana L., Weinmann, Annika Langborg, Nikitidis, Antonios, Zlatoidsky, Pavol, Su, Wu, Czechtizky, Werngard, De Maria, Leonardo, Sormanni, Pietro, Vendruscolo, Michele

“…Non-natural amino acids are increasingly used as building blocks in the development of peptide-based drugs as they expand the available chemical space to…”
Get full text

Controlling the bioactivity of a peptide hormone in vivo by reversible self-assembly by Ouberai, Myriam M., Dos Santos, Ana L. Gomes, Kinna, Sonja, Madalli, Shimona, Hornigold, David C., Baker, David, Naylor, Jacqueline, Sheldrake, Laura, Corkill, Dominic J., Hood, John, Vicini, Paolo, Uddin, Shahid, Bishop, Steven, Varley, Paul G., Welland, Mark E.

“…The use of peptides as therapeutic agents is undergoing a renaissance with the expectation of new drugs with enhanced levels of efficacy and safety. Their…”
Get full text

Self-assembled GLP-1/glucagon peptide nanofibrils prolong inhibition of food intake by Ouberai, Myriam M, Gomes Dos Santos, Ana L, Kinna, Sonja, Hornigold, David C, Baker, David, Naylor, Jacqueline, Liang, Lihuan, Corkill, Dominic J, Welland, Mark E

“…Oxyntomodulin (Oxm) hormone peptide has a number of beneficial effects on nutrition and metabolism including increased energy expenditure and reduced body…”
Get full text

Thermo-Responsive self-assembly of a dual glucagon-like peptide and glucagon receptor agonist by Kinna, Sonja, Ouberaï, Myriam M., Sonzini, Silvia, Gomes Dos Santos, Ana L., Welland, Mark E.

“…The discovery of functional amyloids has inspired tunable self-assembled materials composed of amyloid-like systems. Nanofibrils formed by the human peptide…”
Get full text

Control of Peptide Aggregation and Fibrillation by Physical PEGylation by Ambrosio, Elena, Podmore, Adrian, Gomes dos Santos, Ana L, Magarkar, Aniket, Bunker, Alex, Caliceti, Paolo, Mastrotto, Francesca, van der Walle, Christopher F, Salmaso, Stefano

“…Peptide therapeutics have the potential to self-associate, leading to aggregation and fibrillation. Noncovalent PEGylation offers a strategy to improve their…”
Get full text

Sustained release of nanosized complexes of polyethylenimine and anti-TGF-β2 oligonucleotide improves the outcome of glaucoma surgery by Gomes dos Santos, Ana L., Bochot, Amélie, Doyle, Aoife, Tsapis, Nicolas, Siepmann, Juergen, Siepmann, Florence, Schmaler, Jeannette, Besnard, Madeleine, Behar-Cohen, Francine, Fattal, Elias

“…The purpose of this study was to design microspheres combining sustained delivery and enhanced intracellular penetration for ocular administration of antisense…”
Get full text

Developing an injectable co-formulation of two antidiabetic drugs: Excipient impact on peptide aggregation and pharmacokinetic properties by Lainé, Anne-Laure, Houvenagel, Sophie, Broo, Anders, Jones, Ian, Goodman, Joanne, Corkill, Dominic, Rose, Jonathan, Coward, Sam, Sandinge, Ann-Sofie, Petrone, Marcella, Jermutus, Lutz, Santos, Ana L Gomes Dos

“…[Display omitted] Combination therapy in Type 2 Diabetes Mellitus is necessary to achieve tight glycaemic control and reduce complication risk. Current…”
Get full text

Sustained release of nanosized complexes of polyethylenimine and anti-TGF-beta 2 oligonucleotide improves the outcome of glaucoma surgery by Gomes dos Santos, Ana L, Bochot, Amélie, Doyle, Aoife, Tsapis, Nicolas, Siepmann, Juergen, Siepmann, Florence, Schmaler, Jeannette, Besnard, Madeleine, Behar-Cohen, Francine, Fattal, Elias

“…The purpose of this study was to design microspheres combining sustained delivery and enhanced intracellular penetration for ocular administration of antisense…”
Get full text

Oligonucleotide-polyethylenimine complexes targeting retinal cells : Structural analysis and application to anti-TGFβ-2 therapy by GOMES DOS SANTOS, Ana L, BOCHOT, Amélie, TSAPIS, Nicolas, ARTZNER, Franck, ANTOINE BEJJANI, Riad, THILLAYE-GOLDENBERG, Brigitte, DE KOZAK, Yvonne, FATTAL, Elias, BEHAR-COHEN, Francine

“…Purpose: The aim of this study was to characterize oligonucleotide-polyethylenimine (ODN/PEI) complex preparation for potential transfection of retinal cells…”
Get full text

Oligonucleotide-polyethylenimine complexes targeting retinal cells: structural analysis and application to anti-TGFbeta-2 therapy by Gomes dos Santos, Ana L, Bochot, Amélie, Tsapis, Nicolas, Artzner, Franck, Bejjani, Riad Antoine, Thillaye-Goldenberg, Brigitte, de Kozak, Yvonne, Fattal, Elias, Behar-Cohen, Francine

“…The aim of this study was to characterize oligonucleotide-polyethylenimine (ODN/PEI) complex preparation for potential transfection of retinal cells in vitro…”
Get full text

Oligonucleotide-Polyethylenimine Complexes Targeting Retinal Cells: Structural Analysis and Application to Anti-TGF[beta]-2 Therapy by Ana L. Gomes dos Santos, Bochot, Amélie, Tsapis, Nicolas, Artzner, Franck, Bejjani, Riad Antoine, Thillaye-Goldenberg, Brigitte, de Kozak, Yvonne, Fattal, Elias, Behar-Cohen, Francine

“…The aim of this study was to characterize oligonucleotide-polyethylenimine (ODN/PEI) complex preparation for potential transfection of retinal cells in vitro…”
Get full text