Search Results - "Gomes Dias, Sandra Martha"

GLS2 is protumorigenic in breast cancers by Dias, Marilia M., Adamoski, Douglas, dos Reis, Larissa M., Ascenção, Carolline F. R., de Oliveira, Krishina R. S., Mafra, Ana Carolina Paschoalini, da Silva Bastos, Alliny Cristiny, Quintero, Melissa, de G. Cassago, Carolina, Ferreira, Igor M., Fidelis, Carlos H. V., Rocco, Silvana A., Bajgelman, Marcio Chaim, Stine, Zachary, Berindan-Neagoe, Ioana, Calin, George A., Ambrosio, Andre Luis Berteli, Dias, Sandra Martha Gomes

“…Many types of cancers have a well-established dependence on glutamine metabolism to support survival and growth, a process linked to glutaminase 1 (GLS)…”
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Leptin Signaling Suppression in Macrophages Improves Immunometabolic Outcomes in Obesity by de Brito Monteiro, Lauar, Silveira Prodonoff, Juliana, Favero de Aguiar, Cristhiane, Correa-da-Silva, Felipe, Castoldi, Angela, van Teijlingen Bakker, Nikki, Gastão Davanzo, Gustavo, Castelucci, Bianca, Aparecida da Silva Pereira, Jéssica, Curtis, Jonathan, Büscher, Jörg, Menezes Dos Reis, Larissa, Castro, Gisele, Ribeiro, Guilherme, Victor Virgílio-da-Silva, João, Adamoski, Douglas, Martha Gomes Dias, Sandra, Consonni, Silvio Roberto, Donato, Jose, Pearce, Edward J, Câmara, Niels Olsen Saraiva, Moraes-Vieira, Pedro M

“…Obesity is a major concern for global healthcare systems. Systemic low-grade inflammation in obesity is a major risk factor for insulin resistance. Leptin is…”
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Guanylate-binding protein-1 is a potential new therapeutic target for triple-negative breast cancer by Quintero, Melissa, Adamoski, Douglas, Reis, Larissa Menezes Dos, Ascenção, Carolline Fernanda Rodrigues, Oliveira, Krishina Ratna Sousa de, Gonçalves, Kaliandra de Almeida, Dias, Marília Meira, Carazzolle, Marcelo Falsarella, Dias, Sandra Martha Gomes

“…Triple-negative breast cancer (TNBC) is characterized by a lack of estrogen and progesterone receptor expression (ESR and PGR, respectively) and an absence of…”
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FAK Forms a Complex with MEF2 to Couple Biomechanical Signaling to Transcription in Cardiomyocytes by Cardoso, Alisson Campos, Pereira, Ana Helena Macedo, Ambrosio, Andre Luis Berteli, Consonni, Silvio Roberto, Rocha de Oliveira, Renata, Bajgelman, Marcio Chain, Dias, Sandra Martha Gomes, Franchini, Kleber Gomes

“…Focal adhesion kinase (FAK) has emerged as a mediator of mechanotransduction in cardiomyocytes, regulating gene expression during hypertrophic remodeling…”
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Dual inhibition of glutaminase and carnitine palmitoyltransferase decreases growth and migration of glutaminase inhibition–resistant triple-negative breast cancer cells by Reis, Larissa Menezes dos, Adamoski, Douglas, Ornitz Oliveira Souza, Rodolpho, Rodrigues Ascenção, Carolline Fernanda, Sousa de Oliveira, Krishina Ratna, Corrêa-da-Silva, Felipe, Malta de Sá Patroni, Fábio, Meira Dias, Marília, Consonni, Sílvio Roberto, Mendes de Moraes-Vieira, Pedro Manoel, Silber, Ariel Mariano, Dias, Sandra Martha Gomes

“…Triple-negative breast cancers (TNBCs) lack progesterone and estrogen receptors and do not have amplified human epidermal growth factor receptor 2, the main…”
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HuR controls glutaminase RNA metabolism by Adamoski, Douglas, M. dos Reis, Larissa, Mafra, Ana Carolina Paschoalini, Corrêa-da-Silva, Felipe, Moraes-Vieira, Pedro Manoel Mendes de, Berindan-Neagoe, Ioana, Calin, George A., Dias, Sandra Martha Gomes

“…Glutaminase (GLS) is directly related to cell growth and tumor progression, making it a target for cancer treatment. The RNA-binding protein HuR (encoded by…”
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The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats by Pasquali, Camila Cristina, Islam, Zeyaul, Adamoski, Douglas, Ferreira, Igor Monteze, Righeto, Ricardo Diogo, Bettini, Jefferson, Portugal, Rodrigo Villares, Yue, Wyatt Wai-yin, Gonzalez, Ana, Dias, Sandra Martha Gomes, Ambrosio, Andre Luis Berteli

“…On the basis of tissue-specific enzyme activity and inhibition by catalytic products, Hans Krebs first demonstrated the existence of multiple glutaminases in…”
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Active Glutaminase C Self-assembles into a Supratetrameric Oligomer That Can Be Disrupted by an Allosteric Inhibitor by Ferreira, Amanda Petrina Scotá, Cassago, Alexandre, Gonçalves, Kaliandra de Almeida, Dias, Marília Meira, Adamoski, Douglas, Ascenção, Carolline Fernanda Rodrigues, Honorato, Rodrigo Vargas, de Oliveira, Juliana Ferreira, Ferreira, Igor Monteze, Fornezari, Camila, Bettini, Jefferson, Oliveira, Paulo Sérgio Lopes, Paes Leme, Adriana Franco, Portugal, Rodrigo Villares, Ambrosio, Andre Luis Berteli, Dias, Sandra Martha Gomes

“…The phosphate-dependent transition between enzymatically inert dimers into catalytically capable tetramers has long been the accepted mechanism for the…”
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Human mitochondrial pyruvate carrier 2 as an autonomous membrane transporter by Nagampalli, Raghavendra Sashi Krishna, Quesñay, José Edwin Neciosup, Adamoski, Douglas, Islam, Zeyaul, Birch, James, Sebinelli, Heitor Gobbi, Girard, Richard Marcel Bruno Moreira, Ascenção, Carolline Fernanda Rodrigues, Fala, Angela Maria, Pauletti, Bianca Alves, Consonni, Sílvio Roberto, de Oliveira, Juliana Ferreira, Silva, Amanda Cristina Teixeira, Franchini, Kleber Gomes, Leme, Adriana Franco Paes, Silber, Ariel Mariano, Ciancaglini, Pietro, Moraes, Isabel, Dias, Sandra Martha Gomes, Ambrosio, Andre Luis Berteli

“…The active transport of glycolytic pyruvate across the inner mitochondrial membrane is thought to involve two mitochondrial pyruvate carrier subunits, MPC1 and…”
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N-terminal phosphorylation of glutaminase C decreases its enzymatic activity and cancer cell migration by Ascenção, Carolline Fernanda Rodrigues, Nagampalli, Raghavendra Sashi Krishna, Islam, Zeyaul, Pinheiro, Matheus Pinto, Menezes dos Reis, Larissa, Pauletti, Bianca Alves, de Guzzi Cassago, Carolina Aparecida, Granato, Daniela Campos, Paes Leme, Adriana Franco, Dias, Sandra Martha Gomes

“…The mitochondrial phosphate-activated glutaminase C (GAC) is produced by the alternative splicing of the GLS gene. Compared to the other GLS isoform, the…”
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Glutaminase Affects the Transcriptional Activity of Peroxisome Proliferator-Activated Receptor γ (PPARγ) via Direct Interaction by de Guzzi Cassago, Carolina Aparecida, Dias, Marília Meira, Pinheiro, Matheus Pinto, Pasquali, Camila Cristina, Bastos, Alliny Cristiny Silva, Islam, Zeyaul, Consonni, Sílvio Roberto, de Oliveira, Juliana Ferreira, Gomes, Emerson Machi, Ascenção, Carolline Fernanda Rodrigues, Honorato, Rodrigo, Pauletti, Bianca Alves, Indolfo, Nathalia de Carvalho, Filho, Helder Veras Ribeiro, de Oliveira, Paulo Sergio Lopes, Figueira, Ana Carolina Migliorini, Paes Leme, Adriana Franco, Ambrosio, Andre Luis Berteli, Dias, Sandra Martha Gomes

“…Phosphate-activated glutaminases catalyze the deamidation of glutamine to glutamate and play key roles in several physiological and pathological processes. In…”
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Disclosing quantitative RT‐PCR raw data during manuscript submission: a call for action by Untergasser, Andreas, Hellemans, Jan, Pfaffl, Michael W., Ruijter, Jan M., Hoff, Maurice J. B., Dragomir, Mihnea P., Adamoski, Douglas, Dias, Sandra Martha Gomes, Reis, Rui Manuel, Ferracin, Manuela, Dias‐Neto, Emmanuel, Marsh, Ian, Kubista, Mikael, Fabbri, Muller, Goel, Ajay, Slabý, Ondřej, Knutsen, Erik, Chen, Baoqing, Negrini, Massimo, Mimori, Koshi, Pichler, Martin, Papatriantafyllou, Maria, Anfossi, Simone, Schmittgen, Thomas D., Huggett, Jim, Bustin, Stephen, Vandesompele, Jo, Calin, George A.

“…Accuracy and transparency of scientific data are becoming more and more relevant with the increasing concern regarding the evaluation of data reproducibility…”
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Correction to: New insights in gene expression alteration as effect of doxorubicin drug resistance in triple negative breast cancer cells by Ciocan-Cartita, Cristina Alexandra, Jurj, Ancuta, Zanoaga, Oana, Cojocneanu, Roxana, Pop, Laura-Ancuta, Moldovan, Alin, Moldovan, Cristian, Zimta, Alina Andreea, Raduly, Lajos, Pop-Bica, Cecilia, Buse, Mihail, Budisan, Liviuta, Virag, Piroska, Irimie, Alexandru, Gomes Dias, Sandra Martha, Berindan-Neagoe, Ioana, Braicu, Cornelia

“…An amendment to this paper has been published and can be accessed via the original article…”
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Insights on the Quest for the Structure–Function Relationship of the Mitochondrial Pyruvate Carrier by Quesñay, José Edwin Neciosup, Pollock, Naomi L., Nagampalli, Raghavendra Sashi Krishna, Lee, Sarah C., Balakrishnan, Vijayakumar, Dias, Sandra Martha Gomes, Moraes, Isabel, Dafforn, Tim R., Ambrosio, Andre Luis Berteli

“…The molecular identity of the mitochondrial pyruvate carrier (MPC) was presented in 2012, forty years after the active transport of cytosolic pyruvate into the…”
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The Crystal Structure of Necrosis- and Ethylene-Inducing Protein 2 from the Causal Agent of Cacao’s Witches’ Broom Disease Reveals Key Elements for Its Activity by Zaparoli, Gustavo, Barsottini, Mario Ramos de Oliveira, de Oliveira, Juliana Ferreira, Dyszy, Fabio, Teixeira, Paulo José Pereira Lima, Barau, Joan Grande, Garcia, Odalys, Costa-Filho, Antonio José, Ambrosio, Andre Luis Berteli, Pereira, Gonçalo Amarante Guimarães, Dias, Sandra Martha Gomes

“…The necrosis- and ethylene-inducing peptide 1 (NEP1)-like proteins (NLPs) are proteins secreted from bacteria, fungi and oomycetes, triggering immune responses…”
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Structural Rearrangements in the Thyroid Hormone Receptor Hinge Domain and Their Putative Role in the Receptor Function by Nascimento, Alessandro S., Dias, Sandra Martha Gomes, Nunes, Fábio M., Aparício, Ricardo, Ambrosio, Andre L.B., Bleicher, Lucas, Figueira, Ana Carolina M., Santos, Maria Auxiliadora M., Neto, Mário de Oliveira, Fischer, Hannes, Togashi, Marie, Craievich, Aldo F., Garratt, Richard C., Baxter, John D., Webb, Paul, Polikarpov, Igor

“…The thyroid hormone receptor (TR) D-domain links the ligand-binding domain (LBD, EF-domain) to the DNA-binding domain (DBD, C-domain), but its structure, and…”
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Chemical Elicitors Induce Rare Bioactive Secondary Metabolites in Deep-Sea Bacteria under Laboratory Conditions by de Felício, Rafael, Ballone, Patricia, Bazzano, Cristina Freitas, Alves, Luiz F G, Sigrist, Renata, Infante, Gina Polo, Niero, Henrique, Rodrigues-Costa, Fernanda, Fernandes, Arthur Zanetti Nunes, Tonon, Luciane A C, Paradela, Luciana S, Costa, Renna Karoline Eloi, Dias, Sandra Martha Gomes, Dessen, Andréa, Telles, Guilherme P, da Silva, Marcus Adonai Castro, Lima, Andre Oliveira de Souza, Trivella, Daniela Barretto Barbosa

“…Bacterial genome sequencing has revealed a vast number of novel biosynthetic gene clusters (BGC) with potential to produce bioactive natural products. However,…”
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Low-Resolution Structures of Thyroid Hormone Receptor Dimers and Tetramers in Solution by Figueira, Ana Carolina Migliorini, de Oliveira Neto, Mario, Bernardes, Amanda, Gomes Dias, Sandra Martha, Craievich, Aldo F, Baxter, John D, Webb, Paul, Polikarpov, Igor

“…High-resolution X-ray structures of thyroid hormone (TH) receptor (TR) DNA and ligand binding domains (DBD and LBD) have yielded significant insights into TR…”
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Molecular mechanism of glutaminase activation through filamentation and the role of filaments in mitophagy protection by Adamoski, Douglas, Dias, Marilia Meira, Quesñay, Jose Edwin Neciosup, Yang, Zhengyi, Zagoriy, Ievgeniia, Steyer, Anna M., Rodrigues, Camila Tanimoto, da Silva Bastos, Alliny Cristiny, da Silva, Bianca Novaes, Costa, Renna Karoline Eloi, de Abreu, Flávia Mayumi Odahara, Islam, Zeyaul, Cassago, Alexandre, van Heel, Marin Gerard, Consonni, Sílvio Roberto, Mattei, Simone, Mahamid, Julia, Portugal, Rodrigo Villares, Ambrosio, Andre Luis Berteli, Dias, Sandra Martha Gomes

“…Glutaminase (GLS), which deaminates glutamine to form glutamate, is a mitochondrial tetrameric protein complex. Although inorganic phosphate (Pi) is known to…”
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Different biological effects of exposure to far-UVC (222 nm) and near-UVC (254 nm) irradiation by Tavares, Renata Spagolla Napoleão, Adamoski, Douglas, Girasole, Alessandra, Lima, Ellen Nogueira, da Silva Justo-Junior, Amauri, Domingues, Romênia, Silveira, Ana Clara Caznok, Marques, Rafael Elias, de Carvalho, Murilo, Ambrosio, Andre Luis Berteli, Leme, Adriana Franco Paes, Dias, Sandra Martha Gomes

“…Ultraviolet C (UVC) light has long been used as a sterilizing agent, primarily through devices that emit at 254 nm. Depending on the dose and duration of…”
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