Search Results - "Gomes Azevedo, Edmundo"
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Polymorphism in Pharmaceutical Drugs by Supercritical CO2 Processing: Clarifying the Role of the Antisolvent Effect and Atomization Enhancement
Published in Crystal growth & design (02-11-2016)“…Supercritical carbon dioxide (scCO2) induces polymorphism in pharmaceutical drugs. However, it is unclear whether polymorphism is induced by the CO2…”
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Tuning physicochemical properties of theophylline by cocrystallization using the supercritical fluid enhanced atomization technique
Published in The Journal of supercritical fluids (01-02-2014)“…•Theophylline is cocrystallized with different coformers by using the supercritical enhanced atomization process.•The use of different coformers generates…”
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Single-Step Co-Crystallization and Lipid Dispersion by Supercritical Enhanced Atomization
Published in Crystal growth & design (06-11-2013)“…This work evaluates the feasibility of the supercritical enhanced atomization (SEA) process to improve stability and delivery of active pharmaceutical…”
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Formation of indomethacin–saccharin cocrystals using supercritical fluid technology
Published in European journal of pharmaceutical sciences (12-08-2009)“…The main objective of the present work is to check the feasibility of supercritical fluid (SCF) technologies in the screening and design of cocrystals (novel…”
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Development of a novel mucosal vaccine against strangles by supercritical enhanced atomization spray-drying of Streptococcus equi extracts and evaluation in a mouse model
Published in European journal of pharmaceutics and biopharmaceutics (01-10-2012)“…SDS–PAGE and Western-blot analysis showing integrity and immunoreactivity of Streptococcus equi enzymatic extract antigen processed by the supercritical…”
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Calculation of Solid−Liquid−Gas Equilibrium for Binary Systems Containing CO2
Published in Industrial & engineering chemistry research (06-05-2009)“…Two equations typically used for the pure-solid fugacity proved to be identical by selecting an appropriate relation for the pure-solid vapor pressure and the…”
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Modeling of the PGSS process by crystallization and atomization
Published in AIChE journal (01-08-2005)“…A particles from gas‐saturated solution (PGSS) process for the model system hydrogenated palm oil (HPO) with CO2 was implemented and particle information,…”
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Theophylline polymorphs by atomization of supercritical antisolvent induced suspensions
Published in The Journal of supercritical fluids (01-09-2011)“…[Display omitted] ► We developed ASAIS: the Atomization of Supercritical Antisolvent Induced Suspensions. ► A TPL polymorph, exclusive of SC-CO 2 anti-solvent…”
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Powder X-ray diffraction method for the quantification of cocrystals in the crystallization mixture
Published in Drug development and industrial pharmacy (01-08-2012)“…Context: The solid state purity of cocrystals critically affects their performance. Thus, it is important to accurately quantify the purity of cocrystals in…”
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New Thermoresistant Polymorph from CO2 Recrystallization of Minocycline Hydrochloride
Published in Pharmaceutical research (01-11-2014)“…Purpose To prepare and thoroughly characterize a new polymorph of the broad-spectrum antibiotic minocycline from its hydrochloride dehydrate salts. Methods The…”
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Binary solid–liquid–gas equilibrium of the tripalmitin/CO2 and ubiquinone/CO2 systems
Published in Fluid phase equilibria (15-03-2006)Get full text
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Thermodynamics of Liquid Mixtures of Xenon with Alkanes: (Xenon + Ethane) and (Xenon + Propane)
Published in The journal of physical chemistry. B (17-02-2000)“…Total vapor pressures for liquid mixtures of xenon + ethane at 161.40 and 182.34 K and of xenon + propane at 161.40, 182.34, and 195.49 K have been measured…”
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VLE of Carbon Dioxide/Ethanol/Water: Applications to Volume Expansion Evaluation and Water Removal Efficiency
Published in Industrial & engineering chemistry research (17-08-2005)“…The Peng−Robinson equation of state (PR-EoS) and the Stryjek and Vera modification of the Peng−Robinson equation of state (PRSV-EoS) were used to predict the…”
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Screening for pharmaceutical cocrystals using the supercritical fluid enhanced atomization process
Published in The Journal of supercritical fluids (01-06-2010)“…The supercritical fluid enhanced atomization (SEA) process was used to produce cocrystals of six different active pharmaceutical ingredients (APIs):…”
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Insight into the Mechanisms of Cocrystallization of Pharmaceuticals in Supercritical Solvents
Published in Crystal growth & design (01-07-2015)“…Carbon dioxide has been extensively used as a green solvent medium for the crystallization of active pharmaceutical ingredients (APIs) by replacing harmful…”
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Anti-solvent effect in the production of lysozyme nanoparticles by supercritical fluid-assisted atomization processes
Published in The Journal of supercritical fluids (01-04-2009)“…Particles of lysozyme in the range of 0.1–5 μm were generated by high pressure CO 2 or N 2 (at pressures between 8 MPa and 25 MPa) from aqueous ethanol…”
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Binary and Ternary Phase Behavior of α-Pinene, β-Pinene, and Supercritical Ethene
Published in Journal of chemical and engineering data (1996)“…High-pressure isothermal vapor−liquid equilibria have been measured for binary and ternary systems containing α-pinene, β-pinene, and supercritical ethene, at…”
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Journal Article Conference Proceeding -
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Vapor–liquid equilibria and volume expansion of the tetrahydrofuran/CO2 system: Application to a SAS-atomization process
Published in The Journal of supercritical fluids (01-07-2007)Get full text
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Calculation of Solid−Liquid−Gas Equilibrium for Binary Systems Containing CO 2
Published in Industrial & engineering chemistry research (06-05-2009)Get full text
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