Search Results - "Gomes, Perpetua"

Tracing the Impact of Public Health Interventions on HIV-1 Transmission in Portugal Using Molecular Epidemiology by Vasylyeva, Tetyana I, du Plessis, Louis, Pineda-Peña, Andrea C, Kühnert, Denise, Lemey, Philippe, Vandamme, Anne-Mieke, Gomes, Perpétua, Camacho, Ricardo J, Pybus, Oliver G, Abecasis, Ana B, Faria, Nuno R

“…Estimation of temporal changes in human immunodeficiency virus (HIV) transmission patterns can help to elucidate the impact of preventive strategies and public…”
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MARVEL-minimising the emergence and dissemination of HIV-1 drug resistance in Portuguese-speaking African Countries (PALOP): low-cost portable NGS platform for HIV-1 surveillance in Africa by Sebastião, Cruz S, Pingarilho, Marta, Bathy, Jamila, Bonfim, Elizângela, Toancha, Katia, Miranda, Mafalda N S, Martins, M Rosário O, Gomes, Perpetua, Lázaro, Lazismino, Pina-Araujo, Isabel, Nhampossa, Tacilta, Leal, Silvania, Abecasis, Ana B, Pimentel, Victor

“…HIV-1 infections remain a global public health concern. Scaled-up antiretroviral treatment (ART) is crucial for reducing morbidity and mortality related to…”
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Origin and epidemiological history of HIV-1 CRF14_BG by Bártolo, Inês, Abecasis, Ana B, Borrego, Pedro, Barroso, Helena, McCutchan, Francine, Gomes, Perpétua, Camacho, Ricardo, Taveira, Nuno

“…CRF14_BG isolates, originally found in Spain, are characterized by CXCR4 tropism and rapid disease progression. This study aimed to identify the origin of…”
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Assessing transmissibility of HIV-1 drug resistance mutations from treated and from drug-naive individuals by Winand, Raf, Theys, Kristof, Eusébio, Mónica, Aerts, Jan, Camacho, Ricardo J, Gomes, Perpetua, Suchard, Marc A, Vandamme, Anne-Mieke, Abecasis, Ana B

“…OBJECTIVES:Surveillance drug resistance mutations (SDRMs) in drug-naive patients are typically used to survey HIV-1-transmitted drug resistance (TDR). We test…”
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Mutational Correlates of Virological Failure in Individuals Receiving a WHO-Recommended Tenofovir-Containing First-Line Regimen: An International Collaboration by Rhee, Soo-Yon, Varghese, Vici, Holmes, Susan P., Van Zyl, Gert U., Steegen, Kim, Boyd, Mark A., Cooper, David A., Nsanzimana, Sabin, Saravanan, Shanmugam, Charpentier, Charlotte, de Oliveira, Tulio, Etiebet, Mary-Ann A., Garcia, Federico, Goedhals, Dominique, Gomes, Perpetua, Günthard, Huldrych F., Hamers, Raph L., Hoffmann, Christopher J, Hunt, Gillian, Jiamsakul, Awachana, Kaleebu, Pontiano, Kanki, Phyllis, Kantor, Rami, Kerschberger, Bernhard, Marconi, Vincent C., D'amour Ndahimana, Jean, Ndembi, Nicaise, Ngo-Giang-Huong, Nicole, Rokx, Casper, Santoro, Maria M., Schapiro, Jonathan M., Schmidt, Daniel, Seu, Lillian, Sigaloff, Kim C.E., Sirivichayakul, Sunee, Skhosana, Lindiwe, Sunpath, Henry, Tang, Michele, Yang, Chunfu, Carmona, Sergio, Gupta, Ravindra K., Shafer, Robert W.

“…Tenofovir disoproxil fumarate (TDF) genotypic resistance defined by K65R/N and/or K70E/Q/G occurs in 20% to 60% of individuals with virological failure (VF) on…”
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Memory and naive-like regulatory CD4+ T cells expand during HIV-2 infection in direct association with CD4+ T-cell depletion irrespectively of viremia by FOXALL, Russell B, ALBUQUERQUE, Adriana S, SOARES, Rui S, BAPTISTA, Antonio P, CAVALEIRO, Rita, TENDEIRO, Rita, GOMES, Perpetua, VICTORINO, Rui M. M, SOUSA, Ana E

“…The dynamics of CD4(+) regulatory T cells (Treg) during HIV-1 infection remains unclear. To further investigate Treg in this context, we characterized, for the…”
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Molecular epidemiological analysis of paired pol/env sequences from Portuguese HIV type 1 patients by Abecasis, Ana B, Martins, Andreia, Costa, Inês, Carvalho, Ana P, Diogo, Isabel, Gomes, Perpétua, Camacho, Ricardo J

“…The advent of new therapeutic approaches targeting env and the search for efficient anti-HIV-1 vaccines make it necessary to identify the number of recombinant…”
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Quality Control Assessment of Human Immunodeficiency Virus Type 2 (HIV-2) Viral Load Quantification Assays: Results from an International Collaboration on HIV-2 Infection in 2006 by DAMOND, Florence, BENARD, Antoine, FERNS, Bridget, MATHERON, Sophie, CHENE, Geneviève, BRUN-VEZINET, Francoise, RUELLE, Jean, ALABI, Abraham, KUPFER, Bernd, GOMES, Perpetua, RODES, Berta, ALBERT, Jan, BÖNI, Jürg, GARSON, Jeremy

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Detection of JCV or BKV viruria and viremia after kidney transplantation is not associated with unfavorable outcomes by Querido, Sara, Weigert, Andre, Pinto, Iola, Papoila, Ana Luísa, Pessanha, Maria Ana, Gomes, Perpétua, Adragão, Teresa, Paixão, Paulo

“…© 2023 Wiley Periodicals LLC. Studies analyzing the relationship between BK polyomavirus (BKV) or JC polyomavirus (JCV) infection and kidney transplant (KT)…”
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An International Collaboration To Standardize HIV-2 Viral Load Assays: Results from the 2009 ACHIEV2E Quality Control Study by DAMOND, F, BENARD, A, GOTTLIEB, Geoffrey, KUPFER, Bernd, RUELLE, Jean, RODES, Berta, SORIANO, Vicente, WAINBERG, Mark, TAIEB, Audrey, MATHERON, Sophie, CHENE, Genevieve, BRUN-VEZINET, Francoise, BALOTTA, Claudia, BÖNI, Jürg, COTTEN, Matthew, DUQUE, Vitor, FERNS, Bridget, GARSON, Jeremy, GOMES, Perpetua, GONCALVES, Fátima

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HIV-1 diversity and pre-treatment drug resistance in the era of integrase inhibitor among newly diagnosed ART-naïve adult patients in Luanda, Angola by Sebastião, Cruz S., Abecasis, Ana B., Jandondo, Domingos, Sebastião, Joana M. K., Vigário, João, Comandante, Felícia, Pingarilho, Marta, Pocongo, Bárbara, Cassinela, Edson, Gonçalves, Fátima, Gomes, Perpétua, Giovanetti, Marta, Francisco, Ngiambudulu M., Sacomboio, Euclides, Brito, Miguel, Neto de Vasconcelos, Jocelyne, Morais, Joana, Pimentel, Victor

“…The surveillance of drug resistance in the HIV-1 naïve population remains critical to optimizing the effectiveness of antiretroviral therapy (ART), mainly in…”
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Two cases of dolutegravir failure with R263K mutation by Cardoso, Margarida, Baptista, Teresa, Diogo, Isabel, Aleixo, Maria João, Marques, Nuno, Mansinho, Kamal, Gomes, Perpétua

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Kinetics of Torque Teno Virus Viral Load Is Associated with Infection and De Novo Donor Specific Antibodies in the First Year after Kidney Transplantation: A Prospective Cohort Study by Querido, Sara, Martins, Catarina, Gomes, Perpétua, Pessanha, Maria Ana, Arroz, Maria Jorge, Adragão, Teresa, Casqueiro, Ana, Oliveira, Regina, Costa, Inês, Azinheira, Jorge, Paixão, Paulo, Weigert, André

“…Torque teno virus (TTV) was recently identified as a potential biomarker for the degree of immunosuppression, and potentially as a predictor of rejection and…”
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Drivers of HIV-1 transmission: The Portuguese case by Pineda-Peña, Andrea-Clemencia, Pingarilho, Marta, Li, Guangdi, Vrancken, Bram, Libin, Pieter, Gomes, Perpétua, Camacho, Ricardo Jorge, Theys, Kristof, Barroso Abecasis, Ana

“…Portugal has one of the most severe HIV-1 epidemics in Western Europe. Two subtypes circulate in parallel since the beginning of the epidemic. Comparing their…”
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Safety and Efficacy of Triple Therapy With Dolutegravir Plus 2 Nucleoside Reverse Transcriptase Inhibitors in Treatment-Naive Human Immunodeficiency Virus Type 2 Patients: Results From a 48-Week Phase 2 Study by Pacheco, Patrícia, Marques, Nuno, Rodrigues, Paulo, Mansinho, Kamal, Maltez, Fernando, Janeiro, Nuno, Franco, Cláudia, Trigo, Diva, Batista, Joana, Duque, Luís, Lopes, Maria João, Aleixo, Maria João, Silva, Ana Rita, Tavares, Raquel, Alves, João, Peres, Susana, Póvoas, Diana, Lino, Sara, Gomes, Perpétua, Araújo, Vânia, Lopes, Cristina

“…Abstract Background Integrase strand transfer inhibitor–based regimens are recommended for first-line therapy in human immunodeficiency virus type 2 (HIV-2)…”
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Genotypic resistance profiles of HIV-2-infected patients from Cape Verde failing first-line antiretroviral therapy by Moranguinho, Inês, Borrego, Pedro, Gonçalves, Fátima, Gomes, Perpétua, Rocha, José, Barreto, Jorge, Taveira, Nuno

“…The pol gene from HIV-2-infected patients from Cape Verde experiencing virologic failure was sequenced and drug resistance mutations were determined. Most…”
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Management of HIV-2 resistance to antiretroviral therapy in a HIV-1/HIV-2/HBV co-infected patient by Cardoso, Margarida, Vasconcelos, Joana, Baptista, Teresa, Diogo, Isabel, Gonçalves, Fátima, Mansinho, Kamal, Gomes, Perpétua

“…Abstract Background The current standard of care is to start antiretroviral therapy in all patients diagnosed with HIV-1, as for HIV-2 current DHHS guideline…”
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Differential patterns of postmigration HIV-1 infection acquisition among Portuguese immigrants of different geographical origins by Pimentel, Victor Figueiredo, Pingarilho, Marta, Sole, Giordano, Alves, Daniela, Miranda, Mafalda, Diogo, Isabel, Fernandes, Sandra, Pineda-Pena, Andrea, Martins, M. Rosário O., Camacho, Ricardo, Gomes, Perpétua, Abecasis, Ana B.

“…To investigate the dynamics of phylogenetic transmission clusters involving immigrants of Portuguese Speaking Countries living in Portugal. We included genomic…”
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Applying Next-Generation Sequencing to Track HIV-1 Drug Resistance Mutations Circulating in Portugal by Pimentel, Victor, Pingarilho, Marta, Sebastião, Cruz S, Miranda, Mafalda, Gonçalves, Fátima, Cabanas, Joaquim, Costa, Inês, Diogo, Isabel, Fernandes, Sandra, Costa, Olga, Corte-Real, Rita, Martins, M Rosário O, Seabra, Sofia G, Abecasis, Ana B, Gomes, Perpétua

“…The global scale-up of antiretroviral treatment (ART) offers significant health benefits by suppressing HIV-1 replication and increasing CD4 cell counts…”
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High Instantaneous Inhibitory Potential of Bictegravir and the New Spiro-β-Lactam BSS-730A for HIV-2 Isolates from RAL-Naïve and RAL-Failing Patients by Bártolo, Inês, Moranguinho, Inês, Gonçalves, Paloma, Diniz, Ana Rita, Borrego, Pedro, Martin, Francisco, Figueiredo, Inês, Gomes, Perpétua, Gonçalves, Fátima, Alves, Américo J S, Alves, Nuno, Caixas, Umbelina, Pinto, Inês V, Barahona, Isabel, Pinho E Melo, Teresa M V D, Taveira, Nuno

“…Integrase inhibitors (INIs) are an important class of drugs for treating HIV-2 infection, given the limited number of drugs active against this virus. While…”
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