Search Results - "Gomes, Aldrin V."

Western blotting (immunoblotting): history, theory, uses, protocol and problems by Sule, Rasheed, Rivera, Gabriela, Gomes, Aldrin V

“…Western blotting (immunoblotting) is a powerful and commonly used technique that is capable of detecting or semiquantifying an individual protein from complex…”
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MicroRNAs in the regulation of cellular redox status and its implications in myocardial ischemia-reperfusion injury by Carbonell, Teresa, Gomes, Aldrin V.

“…MicroRNAs (miRNAs) are small RNAs that do not encode for proteins and play key roles in the regulation of gene expression. miRNAs are involved in a…”
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Protein purification and analysis: next generation Western blotting techniques by Mishra, Manish, Tiwari, Shuchita, Gomes, Aldrin V

“…Western blotting is one of the most commonly used techniques in molecular biology and proteomics. Since western blotting is a multistep protocol, variations…”
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Proteasome dysfunction in cardiomyopathies by Gilda, Jennifer E., Gomes, Aldrin V.

“…The ubiquitin–proteasome system (UPS) plays a critical role in removing unwanted intracellular proteins and is involved in protein quality control, signalling…”
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NSAIDs and Cardiovascular Diseases: Role of Reactive Oxygen Species by Ghosh, Rajeshwary, Gomes, Aldrin V., Alajbegovic, Azra

“…Nonsteroidal anti-inflammatory drugs (NSAIDs) are the most commonly used drugs worldwide. NSAIDs are used for a variety of conditions including pain,…”
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The necessity of and strategies for improving confidence in the accuracy of western blots by Ghosh, Rajeshwary, Gilda, Jennifer E, Gomes, Aldrin V

“…Western blotting is one of the most commonly used laboratory techniques for identifying proteins and semi-quantifying protein amounts; however, several recent…”
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Identification of the Immunoproteasome as a Novel Regulator of Skeletal Muscle Differentiation by Cui, Ziyou, Hwang, Soyun Michelle, Gomes, Aldrin V.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Triazine herbicide prometryn alters epoxide hydrolase activity and increases cytochrome P450 metabolites in murine livers via lipidomic profiling by Sule, Rasheed O., Morisseau, Christophe, Yang, Jun, Hammock, Bruce D., Gomes, Aldrin V.

“…Oxylipins are a group of bioactive fatty acid metabolites generated via enzymatic oxygenation. They are notably involved in inflammation, pain, vascular tone,…”
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Key Characteristics of Cardiovascular Toxicants by Lind, Lars, Araujo, Jesus A, Barchowsky, Aaron, Belcher, Scott, Berridge, Brian R, Chiamvimonvat, Nipavan, Chiu, Weihsueh A, Cogliano, Vincent J, Elmore, Sarah, Farraj, Aimen K, Gomes, Aldrin V, McHale, Cliona M, Meyer-Tamaki, Kathleen B, Posnack, Nikki Gillum, Vargas, Hugo M, Yang, Xi, Zeise, Lauren, Zhou, Changcheng, Smith, Martyn T

“…The concept of chemical agents having properties that confer potential hazard called key characteristics (KCs) was first developed to identify carcinogenic…”
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Modulation of mitochondrial dysfunction and endoplasmic reticulum stress are key mechanisms for the wide-ranging actions of epoxy fatty acids and soluble epoxide hydrolase inhibitors by Inceoglu, Bora, Bettaieb, Ahmed, Haj, Fawaz G., Gomes, Aldrin V., Hammock, Bruce D.

“…•The mechanism of action of epoxy fatty acids and inhibitors of the soluble epoxide hydrolase pivots on their ability to prevent mitochondrial dysfunction, to…”
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Western Blotting Inaccuracies with Unverified Antibodies: Need for a Western Blotting Minimal Reporting Standard (WBMRS) by Gilda, Jennifer E, Ghosh, Rajeshwary, Cheah, Jenice X, West, Toni M, Bodine, Sue C, Gomes, Aldrin V

“…Western blotting is a commonly used technique in biological research. A major problem with Western blotting is not the method itself, but the use of poor…”
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Regulation of cardiac proteasomes by ubiquitination, SUMOylation, and beyond by Cui, Ziyou, Scruggs, Sarah B, Gilda, Jennifer E, Ping, Peipei, Gomes, Aldrin V

“…Abstract The ubiquitin–proteasome system (UPS) is the major intracellular degradation system, and its proper function is critical to the health and function of…”
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Improving the sensitivity of traditional Western blotting via Streptavidin containing Poly‐horseradish peroxidase (PolyHRP) by Mishra, Manish, Tiwari, Shuchita, Gunaseelan, Anita, Li, Dongyang, Hammock, Bruce D., Gomes, Aldrin V.

“…Immunoassays such as ELISAs and Western blotting have been the common choice for protein validation studies for the past several decades. Technical…”
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Mitochondrial and Proteasome Dysfunction Occurs in the Hearts of Mice Treated with Triazine Herbicide Prometryn by Sule, Rasheed O, Phinney, Brett S, Salemi, Michelle R, Gomes, Aldrin V

“…Prometryn is a methylthio-s-triazine herbicide used to control the growth of annual broadleaf and grass weeds in many cultivated plants. Significant traces of…”
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A Ketogenic Diet in Combination with Gemcitabine Mitigates Pancreatic Cancer-Associated Cachexia in Male and Female KPC Mice by Cortez, Natalia E, Pathak, Suraj, Rodriguez Lanzi, Cecilia, Hong, Brian V, Crone, Ryman, Sule, Rasheed, Wang, Fangyi, Chen, Shuai, Gomes, Aldrin V, Baar, Keith, Mackenzie, Gerardo G

“…Cancer-associated cachexia (CAC) is a critical contributor to pancreatic ductal adenocarcinoma (PDAC) mortality. Thus, there is an urgent need for new…”
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Upregulation of proteasome activity in muscle RING finger 1‐null mice following denervation by Gomes, Aldrin V., Waddell, Dave S., Siu, Rylie, Stein, Matthew, Dewey, Shannamar, Furlow, J. David, Bodine, Sue C.

“…ABSTRACT Deletion of muscle RING finger 1 (MuRF1), an E3 ubiquitin ligase, leads to sparing of muscle mass following denervation. The purpose of this study was…”
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Ibuprofen alters epoxide hydrolase activity and epoxy-oxylipin metabolites associated with different metabolic pathways in murine livers by Tiwari, Shuchita, Yang, Jun, Morisseau, Christophe, Durbin-Johnson, Blythe, Hammock, Bruce D., Gomes, Aldrin V.

“…Over the last decade oxylipins have become more recognized for their involvement in several diseases. Non-steroidal anti-inflammatory drugs (NSAIDs) such as…”
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Nrf2 deficiency promotes apoptosis and impairs PAX7/MyoD expression in aging skeletal muscle cells by Narasimhan, Madhusudhanan, Hong, Jennifer, Atieno, Nancy, Muthusamy, Vasanthi R., Davidson, Christopher J., Abu-Rmaileh, Naser, Richardson, Russell S., Gomes, Aldrin V., Hoidal, John R., Rajasekaran, Namakkal S.

“…Skeletal muscle redox homeostasis is transcriptionally regulated by nuclear erythroid-2-p45-related factor-2 (Nrf2). We recently demonstrated that…”
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Genetics of Proteasome Diseases by Gomes, Aldrin V.

“…The proteasome is a large, multiple subunit complex that is capable of degrading most intracellular proteins. Polymorphisms in proteasome subunits are…”
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Editorial: Post-translational Modifications and Compartmentalized Protein Quality Control in Cardiac Muscle and Disease by Ranek, Mark J., Gomes, Aldrin V., Su, Huabo

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