Search Results - "Gomaa, Mokhtar"
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EGYVIR: An immunomodulatory herbal extract with potent antiviral activity against SARS-CoV-2
Published in PloS one (18-11-2020)“…Due to the challenges for developing vaccines in devastating pandemic situations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), developing…”
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Robust antiviral activity of commonly prescribed antidepressants against emerging coronaviruses: in vitro and in silico drug repurposing studies
Published in Scientific reports (28-07-2022)“…During the current coronavirus disease 2019 (COVID-19) pandemic, symptoms of depression are commonly documented among both symptomatic and asymptomatic…”
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FDA-Approved Drugs with Potent In Vitro Antiviral Activity against Severe Acute Respiratory Syndrome Coronavirus 2
Published in Pharmaceuticals (Basel, Switzerland) (04-12-2020)“…(1) Background: Drug repositioning is an unconventional drug discovery approach to explore new therapeutic benefits of existing drugs. Currently, it emerges as…”
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Common childhood vaccines do not elicit a cross-reactive antibody response against SARS-CoV-2
Published in PloS one (28-10-2020)“…Anecdotal evidence showed a negative correlation between Bacille Calmette-Guérin (BCG) vaccination and incidence of COVID-19. Incidence of the disease in…”
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Induced humoral immunity of different types of vaccines against most common variants of SARS-CoV-2 in Egypt prior to Omicron outbreak
Published in Vaccine (30-07-2022)“…The diversity of SARS-CoV-2 continues to lead to the emergence of new SARS-CoV-2 variants. SARS-CoV-2 antibody assays are crucial in managing the COVID-19…”
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Isolation and Characterization of a Distinct Influenza A Virus from Egyptian Bats
Published in Journal of virology (15-01-2019)“…Recently, two genetically distinct influenza viruses were detected in bats in Guatemala and Peru. We conducted influenza A virus surveillance among four bat…”
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Avian Influenza A(H5N1) and A(H9N2) Seroprevalence and Risk Factors for Infection Among Egyptians: A Prospective, Controlled Seroepidemiological Study
Published in The Journal of infectious diseases (01-05-2015)“…A(H5N1) and A(H9N2) avian influenza viruses are enzootic in Egyptian poultry, and most A (H5N1) human cases since 2009 have occurred in Egypt. Our…”
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Incidence and Seroprevalence of Avian Influenza in a Cohort of Backyard Poultry Growers, Egypt, August 2015-March 2019
Published in Emerging infectious diseases (01-09-2020)“…Currently enzootic avian influenza H5N1, H9N2, and H5N8 viruses were introduced into poultry in Egypt in 2006, 2011, and 2016, respectively. Infections with…”
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Prevalence and determinants of SARS-CoV-2 neutralizing antibodies in Lebanon
Published in Archives of virology (01-07-2022)“…According to the Lebanese Ministry of Public Health, more than 1,053,000 cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection have…”
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Delineating a potent antiviral activity of Cuphea ignea extract loaded nano-formulation against SARS-CoV-2: In silico and in vitro studies
Published in Journal of drug delivery science and technology (01-12-2021)“…The outbreak of coronavirus disease-2019, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a worldwide emerging crisis. Polyphenols…”
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Active surveillance for avian influenza virus, Egypt, 2010-2012
Published in Emerging infectious diseases (01-04-2014)“…Continuous circulation of influenza A(H5N1) virus among poultry in Egypt has created an epicenter in which the viruses evolve into newer subclades and continue…”
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Incidence, household transmission, and neutralizing antibody seroprevalence of Coronavirus Disease 2019 in Egypt: Results of a community-based cohort
Published in PLoS pathogens (01-03-2021)“…SARS-CoV-2 virus is transmitted in closed settings to people in contact with COVID-19 patients such as healthcare workers and household contacts. However,…”
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Sinapic Acid Suppresses SARS CoV-2 Replication by Targeting Its Envelope Protein
Published in Antibiotics (Basel) (11-04-2021)“…SARS CoV-2 is still considered a global health issue, and its threat keeps growing with the emergence of newly evolved strains. Despite the success in…”
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Antiviral activity of chitosan nanoparticles encapsulating silymarin (Sil-CNPs) against SARS-CoV-2 ( and study)
Published in RSC advances (23-05-2022)“…To develop a specific treatment against COVID-19, we investigated silymarin-chitosan nanoparticles (Sil-CNPs) as an antiviral agent against SARS-CoV-2 using in…”
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Evidence of infection with avian, human, and swine influenza viruses in pigs in Cairo, Egypt
Published in Archives of virology (01-02-2018)“…The majority of the Egyptian swine population was culled in the aftermath of the 2009 H1N1 pandemic, but small-scale growing remains. We sampled pigs from…”
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Middle East respiratory syndrome coronavirus: a comprehensive review
Published in Frontiers of medicine (01-06-2016)“…The Middle East respiratory syndrome eoronavirus was first identified in 2012 and has since then remained uncontrolled. Cases have been mostly reported in the…”
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SARS-CoV-2 Genetic Diversity and Lineage Dynamics in Egypt during the First 18 Months of the Pandemic
Published in Viruses (25-08-2022)“…COVID-19 was first diagnosed in Egypt on 14 February 2020. By the end of November 2021, over 333,840 cases and 18,832 deaths had been reported. As part of the…”
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Double-antibody-based nano-biosensing system for the onsite monitoring of SARS-CoV-2 variants
Published in Microsystems & nanoengineering (21-08-2023)“…The fast and reliable diagnosis of COVID-19 is the foremost priority for promoting public health interventions. Therefore, double-antibody-based…”
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MERS coronaviruses in dromedary camels, Egypt
Published in Emerging infectious diseases (01-06-2014)“…We identified the near-full-genome sequence (29,908 nt, >99%) of Middle East respiratory syndrome coronavirus (MERS-CoV) from a nasal swab specimen from a…”
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Serological Evidence of Human Infection with Avian Influenza A H7virus in Egyptian Poultry Growers
Published in PloS one (03-06-2016)“…Avian influenza viruses circulate widely in birds, with occasional human infections. Poultry-exposed individuals are considered to be at high risk of infection…”
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