Search Results - "Golynskiy, Misha V"

Rational design of FRET sensor proteins based on mutually exclusive domain interactions by Merkx, Maarten, Golynskiy, Misha V, Lindenburg, Laurens H, Vinkenborg, Jan L

“…Proteins that switch between distinct conformational states are ideal to monitor and control molecular processes within the complexity of biological systems…”
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Antibody Detection by Using a FRET-Based Protein Conformational Switch by Golynskiy, Misha V., Rurup, W. Frederik, Merkx, Maarten

“…No wash, just go: Classical antibody‐detection methods rely on heterogeneous detection schemes that involve multiple, time‐consuming binding and washing steps…”
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Monitoring bile acid transport in single living cells using a genetically encoded Förster resonance energy transfer sensor by van der Velden, Lieke M., Golynskiy, Misha V., Bijsmans, Ingrid T. G. W., van Mil, Saskia W. C., Klomp, Leo W. J., Merkx, Maarten, van de Graaf, Stan F.J.

“…Bile acids are pivotal for the absorption of dietary lipids and vitamins and function as important signaling molecules in metabolism. Here, we describe a…”
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Highly Diverse Protein Library Based on the Ubiquitous (β/α)8 Enzyme Fold Yields Well-Structured Proteins through in Vitro Folding Selection by Golynskiy, Misha V., Haugner III, John C., Seelig, Burckhard

“…Proper protein folding is a prerequisite for protein stability and enzymatic activity. Although directed evolution can be a powerful tool to investigate…”
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Engineering Protein Switches: Sensors, Regulators, and Spare Parts for Biology and Biotechnology by Golynskiy, Misha V, Koay, Melissa S, Vinkenborg, Jan L, Merkx, Maarten

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De novo enzymes: from computational design to mRNA display by Golynskiy, Misha V, Seelig, Burckhard

“…Enzymes offer cheap, environmentally responsible and highly efficient alternatives to chemical catalysts. The past two decades have seen a significant rise in…”
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In vitro evolution of enzymes by Golynskiy, Misha V, Haugner, 3rd, John C, Morelli, Aleardo, Morrone, Dana, Seelig, Burckhard

“…In the past decade, in vitro evolution techniques have been used to improve the performance or alter the activity of a number of different enzymes and have…”
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Characterization and Structure of the Manganese-Responsive Transcriptional Regulator ScaR by Stoll, Kate E, Draper, William E, Kliegman, Joseph I, Golynskiy, Misha V, Brew-Appiah, Rhoda A. T, Phillips, Rebecca K, Brown, Hattie K, Breyer, Wendy A, Jakubovics, Nicholas S, Jenkinson, Howard F, Brennan, Richard G, Cohen, Seth M, Glasfeld, Arthur

“…The streptococcal coaggregation regulator (ScaR) of Streptococcus gordonii is a manganese-dependent transcriptional regulator. When intracellular manganese…”
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Metal Binding Studies and EPR Spectroscopy of the Manganese Transport Regulator MntR by Golynskiy, Misha V, Gunderson, William A, Hendrich, Michael P, Cohen, Seth M

“…Manganese transport regulator (MntR) is a member of the diphtheria toxin repressor (DtxR) family of transcription factors that is responsible for manganese…”
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Metal-Induced Structural Organization and Stabilization of the Metalloregulatory Protein MntR by Golynskiy, Misha V, Davis, Talib C, Helmann, John D, Cohen, Seth M

“…MntR is a metalloregulatory protein that helps to modulate the level of manganese in Bacillus subtilis. MntR shows a metal-response profile distinct from other…”
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novo enzymes: from computational design to mRNA display by Golynskiy, Misha V, Seelig, Burckhard

“…Enzymes offer cheap, environmentally responsible and highly efficient alternatives to chemical catalysts. The past two decades have seen a significant rise in…”
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Engineering Protein Switches: Sensors, Regulators, and Spare Parts for Biology and Biotechnology by Golynskiy, Misha V., Koay, Melissa S., Vinkenborg, Jan L., Merkx, Maarten

“…Switch protein switch! Proteins that switch between distinct conformational states are ideal for monitoring and controlling molecular processes in biological…”
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Synthesis and characterization of chromium and molybdenum(0) complexes bearing the (pentafluoroethyl)diphenylphosphine (pfepp) ligand by Palcic, Jason D., Baughman, Russell G., Golynskiy, Misha V., Frawley, Sara B., Peters, R. Gregory

“…Treatment of M(CO) 6 and pfepp in refluxing octane afforded (pfepp)M(CO) 5 (M = Cr 1, Mo 2; pfepp = PPh 2C 2F 5). These complexes were spectroscopically…”
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