Search Results - "Golubovich, V. P."
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Effect of the Ac-D-MPRG Peptide Based on the C-Terminal Fragment of Arginine-Vasopressin(6–9) on the Behavior of Rats of Different Ages
Published in Moscow University biological sciences bulletin (01-06-2023)“…It was found that Ac-D-MPRG, a tetrapeptide synthesized on the basis of the C-terminal fragment of arginine-vasopressin(6–9), affects anxiety and…”
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2
Synthesis and Investigation of the Antidepressant Properties of Novel Analogs of Arginine-Vasopressin
Published in Russian journal of bioorganic chemistry (01-06-2022)“…A search for novel antidepressant analogs of arginine-vasopressin (AVP) by a computer modeling revealed the following peptide analogs of the C -terminal part…”
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3
Mimetics of the Arg-Gly-Asp Sequence: Synthesis and Studies of the Antiaggregative Properties
Published in Russian journal of bioorganic chemistry (01-11-2021)“…— It is known that the Arg-Gly-Asp sequence in the fibrinogen molecule is key in binding to the receptors on the surface of platelets. We searched for the…”
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Modification of Oligopeptides Increasing the Effectiveness of Their Interaction with Interleukin-8 in Human Blood Plasma
Published in Russian journal of bioorganic chemistry (01-03-2020)“…— Molecular modeling, which identified several peptide sequences, was carried out in search for compounds capable of reducing the interleukin-8 concentration…”
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Influence of original structural analogue of arginine-vasopressin(6–9), Ac-D-SPRG, on exploratory activity and level of anxiety of white rats
Published in Moscow University biological sciences bulletin (2012)“…Influence of synthetic analogue of arginine-vasopressin (AVP), Ac-D-SPRG, on exploratory behavior and level of anxiety of white rats was investigated…”
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6
Synthesis of peptide fragments of high-affinity receptor FcepsilonR1 and study their binding with allergen-specific immunoglobulin E
Published in Bioorganicheskaia khimiia (01-05-2012)“…High-affinity receptor FcepsilonR1 is a key substance which participates in IgE-dependent allergic reactions of immediate type. A minimal sequence…”
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New bioaffine sorbents for selective elimination of autoantibodies against human thyroperoxidase in autoimmune thyroid diseases
Published in Biomeditsinskaia khimiia (01-03-2012)“…New bioaffine sorbents containing bioselective ligand, synthetic analog of the human thyroperoxidase antigenic determinant--tetrapeptide…”
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8
The structure-antiaggregative activity relationship in a series of Arg-Gly-Asp analogues
Published in Russian journal of bioorganic chemistry (01-03-2006)“…A series of analogues of Arg-Gly-Asp tripeptide, the common structural element of most of the integrin receptor ligands, possessing different conformational…”
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Effect of N-terminal tripeptides of bombesin, litorin, and their analogue on body temperature and vasomotor responses
Published in Bulletin of experimental biology and medicine (01-08-2007)“…Intranasal administration of bombesin caused hypothermia in rats maintained under cold conditions. N-terminal tripeptide of bombesin exhibits intrinsic…”
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10
Synthesis of modified fragments of fibrinogen and their effect on the activity of proteolytic enzymes
Published in Russian journal of bioorganic chemistry (01-03-2006)“…New analogues of the Gly-Pro-Arg and Arg-Gly-Asp fragments of fibrinogen were synthesized: Gly-Pro-Arg-Pro (I), Gly-Pro-Arg-Pro-Met-OMe (II),…”
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11
The neurotropic activity of a structural analog of ACTH(5-7)
Published in Regulatory peptides (14-04-1994)“…The tripeptide glutamyl-arginyl-proline (ERP) mimicking some structural features of the N-terminal fragment of adrenocorticotropic hormone, ACTH(5-7), has been…”
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12
Improvements in the selective perception and training of rats using an original analog of the C-terminal fragment of vasopressin
Published in Neuroscience and behavioral physiology (01-03-2000)“…This report presents studies on the effects of intranasal administration of five doses (0.001, 0.01, 0.1, 1, and 10 microg/kg) of a new analog of…”
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The effects of a novel analog of the C-terminal fragment of vasopressin on the behavior of white rats
Published in Neuroscience and behavioral physiology (01-07-1999)“…The effects of an arginine-vasopressin fragment, Ac-D-MPRG, on the movement activity and orientational-investigative activity of white rats were studied…”
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14
The analog of arginine-vasopressin (6-9) fragment, Ac-D-SPRG, exhibits antidepressant action in rats in case of intranasal injection
Published in Neurochemical journal (01-07-2015)“…The antidepressant properties of newly synthesized analog of arginine-vasopressin fragment analog, Ac-D-SPRG, were tested using Porsolt’s swimming test on…”
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The effects of analogs of the C-terminal fragment of arginine-vasopressin on the dynamics of development of a conditioned active avoidance response in rats
Published in Neuroscience and behavioral physiology (01-03-1999)“…This paper reports studies of the effects of original analogs of the C-terminal fragment AVP(6-9), D-MPR and D-MPRG, on the development of a conditioned active…”
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The synthesis of peptide fragments of high affinity receptor FcɛRI and their binding to allergen-specific immunoglobulins E
Published in Russian journal of bioorganic chemistry (01-05-2012)“…Using computer analysis, a minimal sequence of Arg136-Asn137-Trp138-Asp139 that can bind to IgE C3 and C4 fragments was determined for the high-affinity…”
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17
The synthesis of peptide fragments of high affinity receptor Fc epsilon RI and their binding to allergen-specific immunoglobulins E
Published in Russian journal of bioorganic chemistry (01-05-2012)“…Using computer analysis, a minimal sequence of Arg136-Asn137-Trp138-Asp139 that can bind to IgE C3 and C4 fragments was determined for the high-affinity…”
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The effect of the glycyl-proline dipeptide on the metabolism of neuroactive amino acids and indices of energy turnover in the neocortex of rats after experimental brain ischemia
Published in Neurochemical journal (01-03-2013)“…We studied the effects of the glycyl-proline dipeptide (Gly-Pro) at a dose of 3 mg/kg on the contents of neuroactive amino acids, including aspartate, glycine,…”
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19
IR spectroscopic analysis of the structure of a biospecific sorbent based on a polyethylene matrix
Published in Journal of applied spectroscopy (01-09-2010)“…We have used IR spectroscopy to study the structure of a biospecific sorbent based on a polyethylene matrix, modified by radiation grafting of acrylic acid…”
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20
The structure-antiaggregative activity relationship in a series of Arg-Gly-Asp analogs
Published in Bioorganicheskaia khimiia (01-03-2006)“…A series of analogues of Arg-Gly-Asp tripeptide, the common structural element of most of the integrin receptor ligands, possessing different conformational…”
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