Search Results - "Golubev, Alexander S."

A new synthesis of N-substituted о-trifluoroacetylanilines by Shidlovskii, Alexander F., Golubev, Alexander S., Gusev, Dmitrii V., Suponitsky, Kyrill Yu, Peregudov, Alexander S., Chkanikov, Nikolai D.

“…Reaction of N-substituted isatoic anhydrides with CF3SiMe3 leads to N-substituted о-trifluoroacetylanilines [Display omitted] ► Synthesis of N-substituted…”
Get full text

Trifluoromethyl-substituted hydantoins, versatile building blocks for rational drug design by Wehner, Volkmar, Stilz, Hans-Ulrich, Osipov, Sergej N, Golubev, Alexander S, Sieler, Joachim, Burger, Klaus

“…Preparatively simple, one-pot syntheses of trifluoromethyl-substituted hydantoins starting from Boc-protected imines of hexafluoroacetone and trifluoropyruvate…”
Get full text

Carbonyl-yne reactions of 3,3,3-trifluoropyruvates by Golubev, Alexander S, Sergeeva, Natalia N, Hennig, Lothar, Kolomiets, Alexey F, Burger, Klaus

“…An efficient synthesis of trifluoromethyl-containing 2,3-allenols via carbonyl-yne reaction of 3,3,3-trifluoropyruvates with acetylenes is described. In the…”
Get full text

Stereoselective syntheses of 4-fluoro- and 4,4-difluoropipecolic acids by Golubev, Alexander S, Schedel, Hartmut, Radics, Gabor, Sieler, Joachim, Burger, Klaus

“…Stereoselective syntheses of 4-fluoro- and 4,4-difluoropipecolic acids starting from Z-protected 4-hydroxy- and 4-oxopipecolates via fluorodehydroxylation and…”
Get full text

A New Strategy for the Synthesis of α-Difluoromethyl-Substituted α-Hydroxy and α-Amino Acids by Osipov, Sergey N, Golubev, Alexander S, Sewald, Norbert, Michel, Thomas, Kolomiets, Alexey F, Fokin, Alexander V, Burger, Klaus

“…A new method for the preparation of α-chlorodifluoromethyl-, α-bromodifluoromethyl-, and α-difluoromethyl-substituted α-hydroxy and α-amino acid esters 11,…”
Get full text

Synthesis of highly fluorinated dipeptide building blocks by Koksch, Beate, Mütze, Kerstin, Osipov, Sergej N, Golubev, Alexander S, Burger, Klaus

“…A new approach to the synthesis of dipeptides containing up to three trifluoromethyl groups has been developed. The method is based on a [4+1]-cycloaddition…”
Get full text

Synthesis and some heterocyclisation reactions of CF2H- and CF2Cl-substituted 1,1-dicyanoethylenes by Golubev, Alexander S, Pasternak, Pavel V, Shidlovskii, Alexander F, Savelèva, Ljudmila N, Averkiev, Boris B, Nesterov, Vladimir N, Antipin, Michail Yu, Peregudov, Alexander S, Chkanikov, Nikolai D

“…Graphic New CF2X-analogues of 1,1-dicyano-2,2-bis(trifluoromethyl)ethylene (1) (X=H, Cl) were synthesised by the condensation of polyfluoroketones with…”
Get full text

Hexafluoroacetone as a protecting and activating reagent: 5,5-difluoro- and trans -5-fluoropipecolic acids from glutamic acid by Golubev, Alexander S., Schedel, Hartmut, Radics, Gabor, Fioroni, Marco, Thust, Sven, Burger, Klaus

Get full text

Synthesis of γ-oxo α-amino acids from L-aspartic acid by Golubev, Alexander S., Sewald, Norbert, Burger, Klaus

“…The synthesis of different γ-oxo α-amino acids from hexafluoroacetone protected L-aspartic acid chloride 1 via Stille cross coupling reaction is described…”
Get full text

Synthesis of highly electrophilic fluorinated alkenyl phosphonates as new precursors of heterocyclic compounds by Chkanikov, Nikolai D., Shidlovskii, Alexander F., Mukhanov, Viktor I., Golubev, Alexander S., Peregudov, Alexander S.

“…New approaches to the synthesis of highly electrophilic fluorinated alkenyl phosphonates as convenient precursors of fluorinecontaining heterocyclic…”
Get full text

New efficient syntheses of α-diflyoromethyl- and α-trifluoromethyl-ornithine by Osipov, Sergey N., Golubev, Alexander S., Sewald, Norbert, Burger, Klaus

“…A new efficient method for the preparation of ornithine derivatives 3–5 is described. The key step of the synthesis is the regioselective alkylation of imine 2…”
Get full text

An improved approach to trifluoromethyl substituted Morita–Baylis–Hillman adduct: Fluorinated dehydro-β-amino acids by Sergeeva, Natalia N., Golubev, Alexander S., Hennig, Lothar, Findeisen, Matthias, Paetzold, Eckhard, Oehme, Günther, Burger, Klaus

“…The [α-(alkoxycarbonyl)vinyl]diisobutylaluminium reagents generated by hydroalumination from α, β-acetylenic esters and DIBAL-H were reacted with N-acylimines…”
Get full text

Peptide Synthesis with α-(Difluoromethyl)-Substituted α-Amino Acids by Michel, Thomas, Koksch, Beate, Osipov, Sergei N., Golubev, Alexander S., Sieler, Joachim, Burger, Klaus

“…Methodology for the incorporation of α-(difluoromethyl)-substituted α-amino acids into N- and C-terminal positions of dipeptides as well as into position 2 of…”
Get full text

Purification, and Biochemical and Biophysical Characterization of Cellobiohydrolase I from Trichoderma harzianum IOC 3844 by Colussi, Francieli, Serpa, Viviane, Da Silva Delabona, Priscila, Manzine, Livia Regina, Voltatodio, Maria Luiza, Alves, Renata, Mello, Bruno Luan, Nei, Pereira Jr, Farinas, Cristiane Sanches, Golubev, Alexander M, Santos, Maria Auxiliadora Morim, Polikarpov, Igor

“…Because of its elevated cellulolytic activity, the filamentous fungus Trichoderma harzianum has a considerable potential in biomass hydrolysis applications…”
Get full text