Search Results - "Golub, T.R."

Circulating tumor DNA association with residual cancer burden after neoadjuvant chemotherapy in triple-negative breast cancer in TBCRC 030 by Parsons, H.A., Blewett, T., Chu, X., Sridhar, S., Santos, K., Xiong, K., Abramson, V.G., Patel, A., Cheng, J., Brufsky, A., Rhoades, J., Force, J., Liu, R., Traina, T.A., Carey, L.A., Rimawi, M.F., Miller, K.D., Stearns, V., Specht, J., Falkson, C., Burstein, H.J., Wolff, A.C., Winer, E.P., Tayob, N., Krop, I.E., Makrigiorgos, G.M., Golub, T.R., Mayer, E.L., Adalsteinsson, V.A.

“…We aimed to examine circulating tumor DNA (ctDNA) and its association with residual cancer burden (RCB) using an ultrasensitive assay in patients with…”
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PAK1 is a breast cancer oncogene that coordinately activates MAPK and MET signaling by Shrestha, Y, Schafer, E J, Boehm, J S, Thomas, S R, He, F, Du, J, Wang, S, Barretina, J, Weir, B A, Zhao, J J, Polyak, K, Golub, T R, Beroukhim, R, Hahn, W C

“…Activating mutations in the RAS family or BRAF frequently occur in many types of human cancers but are rarely detected in breast tumors. However, activation of…”
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Abnormal Gene Expression in Cloned Mice Derived from Embryonic Stem Cell and Cumulus Cell Nuclei by Humpherys, David, Eggan, Kevin, Akutsu, Hidenori, Friedman, Adam, Hochedlinger, Konrad, Yanagimachi, Ryuzo, Lander, Eric S., Golub, Todd R., Jaenisch, Rudolf

“…To assess the extent of abnormal gene expression in clones, we assessed global gene expression by microarray analysis on RNA from the placentas and livers of…”
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Integrative analysis reveals 53BP1 copy loss and decreased expression in a subset of human diffuse large B-cell lymphomas by Takeyama, K, Monti, S, Manis, J P, Cin, P Dal, Getz, G, Beroukhim, R, Dutt, S, Aster, J C, Alt, F W, Golub, T R, Shipp, M A

“…p53-Binding protein 1 ( 53BP1 ) encodes a critical checkpoint protein that localizes to sites of DNA double-strand breaks (DSBs) and participates in DSB…”
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