Partial antigenic structure of group H10 flagellins in Escherichia coli and its genetic determination

The study of flagellar antigens classified with serotype H10 has been made in E. coli belonging to different OK-groups. These antigens have been shown to differ in their partial structure. Group H10 antigens have been found to comprise 7 variants, and their partial structure has been determined. The...

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Bibliographic Details
Published in:	Žurnal mikrobiologii, ėpidemiologii i immunobiologii no. 11; p. 21
Main Authors:	Ratiner, Iu A, Golovushkina, N N, Klimova, Z V
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 01-11-1983
Subjects:	Alleles Antigens, Bacterial - analysis Antigens, Bacterial - genetics Bacterial Proteins - immunology Escherichia coli - genetics Escherichia coli - immunology Flagella - immunology Flagellin - genetics Flagellin - immunology Genes, Bacterial Genetic Variation Transduction, Genetic
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Summary:	The study of flagellar antigens classified with serotype H10 has been made in E. coli belonging to different OK-groups. These antigens have been shown to differ in their partial structure. Group H10 antigens have been found to comprise 7 variants, and their partial structure has been determined. The study has shown that antigenic variants of the same type occur in E. coli belonging to different OK-groups and different variants may occur in strains within the same OK-group. The data obtained in the study of the expression of genes, responsible for the synthesis of flagellin, in the system of isogenic strains suggest that differences in the partial structure between the variants of group H10 antigens are linked with differences between the corresponding alleles of the flagellin-specifying gene. The differentiation of these antigens by means of factor-specific antibodies may prove to be of practical importance for solving the problems of the epidemiology and etiology of diseases caused by E. coli having group H10 flagellar antigens.
ISSN:	0372-9311