Search Results - "Golomb, M"

Single-cell profiling guided combinatorial immunotherapy for fast-evolving CDK4/6 inhibitor-resistant HER2-positive breast cancer by Wang, Qingfei, Guldner, Ian H., Golomb, Samantha M., Sun, Longhua, Harris, Jack A., Lu, Xin, Zhang, Siyuan

“…Acquired resistance to targeted cancer therapy is a significant clinical challenge. In parallel with clinical trials combining CDK4/6 inhibitors to treat…”
Get full text

Role of Counterions in the Structural Stabilisation of Redox‐Active Metal‐Organic Frameworks by Golomb, M. J., Tolborg, K., Calbo, J., Walsh, A.

“…The crystal structures of metal‐organic frameworks (MOFs) are typically determined by the strong chemical bonds formed between the organic and inorganic…”
Get full text

Self-motivated and directed learning across the lifespan by Cronin-Golomb, Lucy M., Bauer, Patricia J.

“…Self-motivated and directed learning is integral to knowledge base expansion for learners of all ages. Both motivational and cognitive processes drive…”
Get full text

Multi-modal Single-Cell Analysis Reveals Brain Immune Landscape Plasticity during Aging and Gut Microbiota Dysbiosis by Golomb, Samantha M., Guldner, Ian H., Zhao, Anqi, Wang, Qingfei, Palakurthi, Bhavana, Aleksandrovic, Emilija A., Lopez, Jacqueline A., Lee, Shaun W., Yang, Kai, Zhang, Siyuan

“…Phenotypic and functional plasticity of brain immune cells contribute to brain tissue homeostasis and disease. Immune cell plasticity is profoundly influenced…”
Get full text

Over 4000 nm bandwidth of mid-IR supercontinuum generation in sub-centimeter segments of highly nonlinear tellurite PCFs by Domachuk, P, Wolchover, N A, Cronin-Golomb, M, Wang, A, George, A K, Cordeiro, C M B, Knight, J C, Omenetto, F G

“…We report broad bandwidth, mid-IR supercontinuum generation using a sub-cm (8 mm) length of highly nonlinear tellurite microstructured photonic crystal fiber…”
Get full text

Targeting CXCL16 and STAT1 augments immune checkpoint blockade therapy in triple-negative breast cancer by Palakurthi, Bhavana, Fross, Shaneann R., Guldner, Ian H., Aleksandrovic, Emilija, Liu, Xiyu, Martino, Anna K., Wang, Qingfei, Neff, Ryan A., Golomb, Samantha M., Lewis, Cheryl, Peng, Yan, Howe, Erin N., Zhang, Siyuan

“…Chemotherapy prior to immune checkpoint blockade (ICB) treatment appears to improve ICB efficacy but resistance to ICB remains a clinical challenge and is…”
Get full text

Support for learning under naturalistic conditions by Cronin-Golomb, Lucy M., Bauer, Patricia J.

“…Educational opportunities occur through naturalistic everyday life experiences (e.g., reading a newspaper, listening to a podcast, or visiting a museum)…”
Get full text

Isolation of mouse brain-infiltrating leukocytes for single cell profiling of epitopes and transcriptomes by Guldner, Ian H., Golomb, Samantha M., Wang, Qingfei, Wang, Emilia, Zhang, Siyuan

“…High dimensional compositional and transcriptional profiling of heterogeneous brain-infiltrating leukocytes can lead to novel biological and therapeutic…”
Get full text

Compact resonant integrated microfluidic refractometer by Domachuk, P., Littler, I. C. M., Cronin-Golomb, M., Eggleton, B. J.

“…We introduce a class of highly compact refractometers integrated onto a planar microfluidic geometry that demonstrates high resolution refractive index…”
Get full text

A novel immunization strategy using cytokine/chemokines induces new effective systemic immune responses, and frequent complete regressions of human metastatic melanoma by Valentine, Fred T., Golomb, Frederick M., Harris, Matthew, Roses, Daniel F.

“…Immune responses have been elicited by a variety of cancer vaccines, but seldom induce regressions of established cancers in humans. As a novel therapeutic…”
Get full text

Optofluidics: a novel generation of reconfigurable and adaptive compact architectures by Monat, C., Domachuk, P., Grillet, C., Collins, M., Eggleton, B. J., Cronin-Golomb, M., Mutzenich, S., Mahmud, T., Rosengarten, G., Mitchell, A.

“…The integration of microfluidics and microphotonics brings the ability to tune and reconfigure ultra-compact optical devices. This flexibility is essentially…”
Get full text

Aspirin reduces the prothrombotic activity of C‐reactive protein by GRAD, E., GOLOMB, M., KOROUKHOV, N., LAWSON, J. A., LOTAN, C., FITZGERALD, G. A., DANENBERG, H. D.

“…Aim: C‐reactive protein (CRP) is a risk marker and a potential modulator of vascular disease. Previous studies support a prothrombotic activity of CRP, with…”
Get full text

Application of optical trapping to beam manipulation in optofluidics by Domachuk, P, Cronin-Golomb, M, Eggleton, B, Mutzenich, S, Rosengarten, G, Mitchell, A

“…We introduce a novel method of attaining all-optical beam control in an optofluidic device by displacing an optically trapped microsphere through a light beam…”
Get full text

CNS-Native Myeloid Cells Drive Immune Suppression in the Brain Metastatic Niche through Cxcl10 by Guldner, Ian H., Wang, Qingfei, Yang, Lin, Golomb, Samantha M., Zhao, Zhuo, Lopez, Jacqueline A., Brunory, Abigail, Howe, Erin N., Zhang, Yizhe, Palakurthi, Bhavana, Barron, Martin, Gao, Hongyu, Xuei, Xiaoling, Liu, Yunlong, Li, Jun, Chen, Danny Z., Landreth, Gary E., Zhang, Siyuan

“…Brain metastasis (br-met) develops in an immunologically unique br-met niche. Central nervous system-native myeloid cells (CNS-myeloids) and…”
Get full text

Steroid-responsive neurologic relapses in a child with a proteolipid protein-1 mutation by GORMAN, M. P, GOLOMB, M. R, WALSH, L. E, HOBSON, G. M, GARBERN, J. Y, KINKEL, R. P, DARRAS, B. T, URION, D. K, EKSIOGLU, Y. Z

“…A 10-year-old boy developed corticosteroid-responsive relapsing neurologic signs, including nystagmus and ataxia. MRI revealed multifocal T2 white matter…”
Get full text

Integration of Memory Content in Adults and Children: Developmental Differences in Task Conditions and Functional Consequences by Bauer, Patricia J., Cronin-Golomb, Lucy M., Porter, Blaire M., Jaganjac, Adna, Miller, Hilary E.

“…How separate yet related episodes of experience are associated in memory is a major question in cognitive science and cognitive neuroscience. Adults and…”
Get full text

The Influence of Books' Textual Features and Caregivers' Extratextual Talk on Children's Science Learning in the Context of Shared Book Reading by Miller-Goldwater, Hilary E., Cronin-Golomb, Lucy M., Hanft, Melanie H., Bauer, Patricia J.

“…During early childhood, reading books with one's caregiver (shared book reading) is a valuable means of supporting learning. Yet, there are gaps in our…”
Get full text

Individual differences diminish the pretest effect under productive memory conditions by Cronin-Golomb, Lucy M, Wilson, Julia T, Miller, Alissa G, Bauer, Patricia J

“…Pretesting, or asking a test question prior to the onset of learning, is a well-established means of enhancing learning. Research on pretesting has focused…”
Get full text

Longitudinal predictors of self-derivation through memory integration—A mechanism of knowledge accumulation by Bauer, Patricia J., Lee, Katherine A., Dugan, Jessica A., Cronin-Golomb, Lucy M.

“…•Knowledge builds via instruction and self-derivation through memory integration.•Concurrent & longitudinal tests of predictors of self-derivation in…”
Get full text

Effect of intracranial bleeds on the neurocognitive, academic, behavioural and adaptive functioning of boys with haemophilia by MILES, B. S., ANDERSON, P., AGOSTINO, A., GOLOMB, M. R., ACHONU, C., BLANCHETTE, V., FELDMAN, B. M., McLIMONT, M., REVEL-VILK, S., STAIN, A., BARNES, M. A.

“…Brain insults are a risk factor for neuropsychological and academic deficits across several paediatric conditions. However, little is known about the specific…”
Get full text