Search Results - "Gollub, Randy L."
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Default mode network connectivity encodes clinical pain: An arterial spin labeling study
Published in Pain (Amsterdam) (01-01-2013)“…Patterns of intrinsic connectivity within the brain encode intensity of clinical pain and predict sustained pain in patients with chronic low back pain…”
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2
Machine learning–based prediction of clinical pain using multimodal neuroimaging and autonomic metrics
Published in Pain (Amsterdam) (01-03-2019)“…Although self-report pain ratings are the gold standard in clinical pain assessment, they are inherently subjective in nature and significantly influenced by…”
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Distinct thalamocortical network dynamics are associated with the pathophysiology of chronic low back pain
Published in Nature communications (07-08-2020)“…Thalamocortical dysrhythmia is a key pathology of chronic neuropathic pain, but few studies have investigated thalamocortical networks in chronic low back pain…”
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4
Nonconscious activation of placebo and nocebo pain responses
Published in Proceedings of the National Academy of Sciences - PNAS (25-09-2012)“…The dominant theories of human placebo effects rely on a notion that consciously perceptible cues, such as verbal information or distinct stimuli in classical…”
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Reproducibility of quantitative tractography methods applied to cerebral white matter
Published in NeuroImage (Orlando, Fla.) (01-07-2007)“…Tractography based on diffusion tensor imaging (DTI) allows visualization of white matter tracts. In this study, protocols to reconstruct eleven major white…”
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Disrupted Brain Circuitry for Pain‐Related Reward/Punishment in Fibromyalgia
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-01-2014)“…Objective While patients with fibromyalgia (FM) are known to exhibit hyperalgesia, the central mechanisms contributing to this altered pain processing are not…”
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Reduced tactile acuity in chronic low back pain is linked with structural neuroplasticity in primary somatosensory cortex and is modulated by acupuncture therapy
Published in NeuroImage (Orlando, Fla.) (15-08-2020)“…Prior studies have shown that patients suffering from chronic Low Back Pain (cLBP) have impaired somatosensory processing including reduced tactile acuity,…”
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Impaired mesocorticolimbic connectivity underlies increased pain sensitivity in chronic low back pain
Published in NeuroImage (Orlando, Fla.) (01-09-2020)“…Chronic low back pain (cLBP) is a prevalent disorder. A growing body of evidence linking the pathology of the reward network to chronic pain suggests that pain…”
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Linking brain structure, cognition, and sleep: insights from clinical data
Published in Sleep (New York, N.Y.) (08-02-2024)“…Abstract Study Objectives To use relatively noisy routinely collected clinical data (brain magnetic resonance imaging (MRI) data, clinical polysomnography…”
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Disrupted functional connectivity of the periaqueductal gray in chronic low back pain
Published in NeuroImage clinical (01-01-2014)“…Chronic low back pain is a common neurological disorder. The periaqueductal gray (PAG) plays a key role in the descending modulation of pain. In this study, we…”
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Distinct neural representations of placebo and nocebo effects
Published in NeuroImage (Orlando, Fla.) (15-05-2015)“…Expectations shape the way we experience the world. In this study, we used fMRI to investigate how positive and negative expectation can change pain…”
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Placebo analgesia and reward processing: Integrating genetics, personality, and intrinsic brain activity
Published in Human brain mapping (01-09-2014)“…Our expectations about an event can strongly shape our subjective evaluation and actual experience of events. This ability, applied to the modulation of pain,…”
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Perturbing fMRI brain dynamics using transcranial direct current stimulation
Published in NeuroImage (Orlando, Fla.) (15-08-2021)“…The dynamic nature of resting-state functional magnetic resonance imaging (fMRI) brain activity and connectivity has drawn great interest in the past decade…”
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14
Patterns of brain activation when mothers view their own child and dog: an fMRI study
Published in PloS one (03-10-2014)“…Neural substrates underlying the human-pet relationship are largely unknown. We examined fMRI brain activation patterns as mothers viewed images of their own…”
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Functional connectivity of the frontoparietal network predicts cognitive modulation of pain
Published in Pain (Amsterdam) (01-03-2013)“…Pretest resting state functional connectivity between the frontoparietal network and the rostral anterior cingulate cortex/medial prefrontal cortex is…”
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A Functional Magnetic Resonance Imaging Study on the Neural Mechanisms of Hyperalgesic Nocebo Effect
Published in The Journal of neuroscience (03-12-2008)“…Previous studies suggest that nocebo effects, sometimes termed "negative placebo effects," can contribute appreciably to a variety of medical symptoms and…”
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Repeated verum but not placebo acupuncture normalizes connectivity in brain regions dysregulated in chronic pain
Published in NeuroImage clinical (2015)“…Acupuncture, an ancient East Asian therapy, is aimed at rectifying the imbalance within the body caused by disease. Studies evaluating the efficacy of…”
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Are all placebo effects equal? Placebo pills, sham acupuncture, cue conditioning and their association
Published in PloS one (31-07-2013)“…Placebo treatments and healing rituals have been used to treat pain throughout history. The present within-subject crossover study examines the variability in…”
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Maturation trajectories of cortical resting-state networks depend on the mediating frequency band
Published in NeuroImage (Orlando, Fla.) (01-07-2018)“…The functional significance of resting state networks and their abnormal manifestations in psychiatric disorders are firmly established, as is the importance…”
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Visual network alterations in brain functional connectivity in chronic low back pain: A resting state functional connectivity and machine learning study
Published in NeuroImage clinical (01-01-2019)“…Chronic low back pain (cLBP) is associated with widespread functional and structural changes in the brain. This study aims to investigate the resting state…”
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