Search Results - "Gollob, M. H."

Phospholamban cardiomyopathy: a Canadian perspective on a unique population by Cheung, C. C., Healey, J. S., Hamilton, R., Spears, D., Gollob, M. H., Mellor, G., Steinberg, C., Sanatani, S., Laksman, Z. W., Krahn, A. D.

“…Introduction Phospholamban cardiomyopathy is an inherited cardiomyopathy, characterised by a defect in regulation of the sarcoplasmic reticulum Ca 2+ pump,…”
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Detection of genomic deletions of PKP2 in arrhythmogenic right ventricular cardiomyopathy by Roberts, JD, Herkert, JC, Rutberg, J, Nikkel, SM, Wiesfeld, ACP, Dooijes, D, Gow, RM, van Tintelen, JP, Gollob, MH

“…Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited myocardial disease that predominantly affects the right ventricle and is associated with…”
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Evolution of a genetic diagnosis by Laksman, Z., Dulay, D., Gollob, M.H., Skanes, A.C., Krahn, A.D.

“…Understanding the relationship between genotype and phenotype has become an integral part of the diagnosis and management of patients with inherited…”
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Glycogen storage disease as a unifying mechanism of disease in the PRKAG2 cardiac syndrome by Gollob, M H

“…The AMP-activated protein kinase (AMPK) system was first discovered 30 years ago. Since that time, knowledge of the diverse physiological functions of AMPK has…”
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A prospective randomized evaluation of a pharmacogenomic approach to antiplatelet therapy among patients with ST-elevation myocardial infarction: the RAPID STEMI study by So, D Y F, Wells, G A, McPherson, R, Labinaz, M, Le May, M R, Glover, C, Dick, A J, Froeschl, M, Marquis, J-F, Gollob, M H, Tran, L, Bernick, J, Hibbert, B, Roberts, J D

“…Treatment of carriers of the CYP2C19*2 allele and ABCB1 TT genotype with clopidogrel is associated with increased ischemic complications after percutaneous…”
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Use of implantable cardioverter defibrillators in Canadian and US survivors of out-of-hospital cardiac arrest by Birnie, David H, Sambell, Christie, Johansen, Helen, Williams, Kathryn, Lemery, Robert, Green, Martin S, Gollob, Michael H, Lee, Douglas S, Tang, Anthony S L

“…Cardiac arrest due to ventricular arrhythmia in the absence of a reversible cause or contraindication has been a class I indication for insertion of an…”
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AMP-activated protein kinase and familial Wolff–Parkinson–White syndrome: new perspectives on heart development and arrhythmogenesis by Gollob, M.H., Roberts, R.

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Identification of a Gene Responsible for Familial Wolff–Parkinson–White Syndrome by Gollob, Michael H, Gollob, Tanya, Green, Martin S, Tang, Anthony S.-L, Karibe, Akihiko, Hassan, Al-Sayegh, Ahmad, Ferhaan, Lozado, Ryan, Shah, Gopi, Fananapazir, Lameh, Bachinski, Linda L, Tapscott, Terry, Gonzales, Oscar, Begley, David, Mohiddin, Saidi, Roberts, Robert

“…Probable causative mutation was identified in a protein kinase gene (PRKAG2) on chromosome 7. The Wolff–Parkinson–White syndrome is the second most common…”
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Novel PRKAG2 mutation responsible for the genetic syndrome of ventricular preexcitation and conduction system disease with childhood onset and absence of cardiac hypertrophy by GOLLOB, Michael H, SEGER, John J, GOLLOB, Tanya N, TAPSCOTT, Terry, GONZALES, Oscar, BACHINSKI, Linda, ROBERTS, Robert

“…We recently reported a mutation in the PRKAG2 gene to be responsible for a familial syndrome of ventricular preexcitation, atrial fibrillation, conduction…”
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Postradiation morphea by Gollob, M H, Dekoven, J G, Bell, M J, Assaad, D, Rao, J

“…We describe a 54-year-old woman who developed right breast morphea after radiotherapy following a lumpectomy for infiltrating lobular carcinoma. Skin biopsy…”
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Current status of the implantable cardioverter-defibrillator by Gollob, M H, Seger, J J

“…Clinical trials have established the superiority of the implantable cardioverter-defibrillator (ICD) over antiarrhythmic drug therapy in survivors of sudden…”
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Somatic Mutations in the Connexin 40 Gene (GJA5) in Atrial Fibrillation by Gollob, Michael H, Jones, Douglas L, Krahn, Andrew D, Danis, Lynne, Gong, Xiang-Qun, Shao, Qing, Liu, Xiaoqin, Veinot, John P, Tang, Anthony S.L, Stewart, Alexandre F.R, Tesson, Frederique, Klein, George J, Yee, Raymond, Skanes, Allan C, Guiraudon, Gerard M, Ebihara, Lisa, Bai, Donglin

“…In 4 of 15 patients with idiopathic atrial fibrillation, four novel, heterozygous mutations in GJA5 — the gene for the gap-junction protein connexin 40 — were…”
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Accessory atrioventricular node with properties of a typical accessory pathway: anatomic-electrophysiologic correlation by Gollob, M H, Bharati, S, Swerdlow, C D

“…We report an accessory AV node producing ventricular preexcitation and comprising the retrograde limb of AV reentrant tachycardia (AVRT). A 66-year-old man…”
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Risk stratification for sudden death in heart failure by Farwell, D, Gollob, M H

“…Clinical trials provide evidence that an empiric approach of implantable cardioverter-defibrillator (ICD) implantation in heart failure patients (ejection…”
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Voltage-gated sodium channels: biophysics, pharmacology, and related channelopathies by Savio-Galimberti, Eleonora, Gollob, Michael H, Darbar, Dawood

“…Voltage-gated sodium channels (VGSC) are multi-molecular protein complexes expressed in both excitable and non-excitable cells. They are primarily formed by a…”
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Evaluation of non-synonymous NPPA single nucleotide polymorphisms in atrial fibrillation by Roberts, Jason D, Davies, Robert W, Lubitz, Steven A, Thibodeau, Isabelle L, Nery, Pablo B, Birnie, David H, Benjamin, Emelia J, Lemery, Robert, Ellinor, Patrick T, Gollob, Michael H

“…Atrial fibrillation (AF), the most common sustained cardiac arrhythmia, is an important cause of morbidity and mortality. A genetic mutation in the NPPA gene,…”
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Frequency of Peripartum Cardiomyopathy by Mielniczuk, Lisa M., Williams, Kathryn, Davis, Darryl R., Tang, Anthony S.L., Lemery, Robert, Green, Martin S., Gollob, Michael H., Haddad, Haissam, Birnie, David H.

“…Reports from case series have estimated the incidence of peripartum cardiomyopathy (PC) at 1 case/1,485 live births to 1 case/15,000 live births and probable…”
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No long-term psychological morbidity living with an implantable cardioverter defibrillator under advisory: the Medtronic Marquis experience by Birnie, David H., Sears, Samuel F., Green, Martin S., Lemery, Robert, Gollob, Michael H., Amyotte, Barbara

“…Aims It is unclear whether there is important psychological morbidity associated with living with an implantable cardioverter defibrillator (ICD) under…”
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Gain-of-function mutation of Na sub(v)1.5 in atrial fibrillation enhances cellular excitability and lowers the threshold for action potential firing by Li, Q, Huang, H, Liu, G, Lam, K, Rutberg, J, Green, MS, Birnie, D H, Lemery, R, Chahine, M, Gollob, M H

“…Genetic mutations of the cardiac sodium channel (SCN5A) specific only to the phenotype of atrial fibrillation have recently been described. However, data on…”
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Ventricular tachycardia following tube thoracotomy by Hibbert, Benjamin, Lim, Toon Wei, Hibbert, Rebecca, Green, Martin, Gollob, Michael H, Davis, Darryl R

“…Arrhythmias provoked by tube thoracotomy are a rare complication. We report a ventricular tachycardia after chest tube insertion for a device-related…”
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