Search Results - "Golimbet, V E"

Assessing the impact of the de novo SLC6A1 mutation in schizophrenia through a comprehensive case study by Kondratyev, NV, Alfimova, MV, Kaleda, VG, Lezheiko, TV, Mikhailova, VA, Karpov, DS, Ublinsky, MV, Ushakov, VL, Lebedeva, IS, Golimbet, VE

“…•The patient with an SLC6A1 mutation, typically linked to disorders like epilepsy and autism, exhibited symptoms consistent with schizophrenia and bipolar…”
Get full text

Effect of VNTR Polymorphism of the AS3MT Gene and Obstetrical Complications on the Severity of Schizophrenia by Korovaitseva, G. I., Gabaeva, M. V., Yunilainen, O. A., Golimbet, V. E.

“…The role of the VNTR polymorphism of the AS3MT gene in determining the clinical features of schizophrenia and schizophrenic spectrum disorders was studied. The…”
Get full text

Studies of the Association between the Kynurenine-3-Monooxygenase Gene and Depression by Lezheiko, T. V., Golimbet, V. E., Andryushchenko, A. V., Melik-Pashayan, A. E., Mironova, E. V.

“…Objective. To study the association between the kynurenine-3-monooxygenase (KMO) gene and depression. Materials and methods . Polymorphic loci rs2275163 (C/T)…”
Get full text

Genome-Wide Studies of the Comorbidity of Somatic and Mental Diseases by Golimbet, V. E., Klyushnik, T. P.

“…Studies of the genomic architecture of complex phenotypes, which include common somatic and mental diseases, have shown them to be characterized by high levels…”
Get full text

Molecular-Genetic and Immunological Aspects of the Formation of Psychopathological Symptoms in Schizophrenia by Golimbet, V. E., Klyushnik, T. P.

“…This review presents data indicating that the formation of the psychopathological symptoms of schizophrenia is due to complex and diverse genetic factors…”
Get full text

The Influence of Genotype on Phenotype in Contemporary Research into the Genetic Causes of Schizophrenia by Golimbet, V. E., Kostyuk, G. P.

“…The aim of the present review was to consider different approaches to establishing genotype–phenotype relationships in schizophrenia taking account of…”
Get full text

Molecular genetic studies of cognitive deficit in schizophrenia by Golimbet, V. E

“…Cognitive deficit is a key feature of schizophrenia. Genetic factors are thought to contribute to cognitive disturbances in schizophrenic patients. However,…”
Get full text

Season of birth/C-reactive protein gene interaction differentially affects negative symptoms domains in patients with schizophrenia by Lezheiko, T. V., Mikhailova, V. A., Gabaeva, M. V., Kolesina, N. Y., Golimbet, V. E.

“…Background Schizophrenia is a severe psychiatric disease caused by genetic and environmental factors or their interactions that can contribute across multiple…”
Get full text

Polymorphism of Serotonin Receptor Genes (5-HTR2A) and Dysbindin (DTNBP1) and Individual Components of Short-Term Verbal Memory Processes in Schizophrenia by Alfimova, M. V., Monakhov, M. V., Abramova, L. I., Golubev, S. A., Golimbet, V. E.

“…Associations between polymorphisms in the T102C and A-1438G loci of the 5-HTR2A and the P1763 and P1578 markers of the DTNBP1 gene with the overall…”
Get full text

Abundance of ribosomal RNA gene copies in the genomes of schizophrenia patients by Chestkov, I.V., Jestkova, E.M., Ershova, E.S., Golimbet, V.E., Lezheiko, T.V., Kolesina, N.Y., Porokhovnik, L.N., Lyapunova, N.A., Izhevskaya, V.L., Kutsev, S.I., Veiko, N.N., Kostyuk, S.V.

“…The ribosome is a critical component of the translation machinery. The key component of ribosomes is ribosomal RNA (rRNA). Dysregulation of rRNA biogenesis has…”
Get full text

Effects of Oxytocin Pathway Gene Polymorphisms and Adverse Childhood Experiences on the Recognition of Emotion in Schizophrenia Spectrum Disorders by Alfimova, M. V., Mikhailova, V. A., Gabaeva, M. V., Plakunova, V. V., Lezheiko, T. V., Golimbet, V. E.

“…Objectives. To assess the role of interactions between oxytocin pathway gene polymorphisms and adverse childhood experiences (ACE) in deficits of the…”
Get full text

Studies of the Relationship between Oxytocinergic System Genes, Perinatal Complications, and the Formation of Interpersonal Relationships in Schizophrenia Patients by Mikhailova, V. A., Lezheiko, T. V., Kolesina, N. Yu, Golimbet, V. E.

“…Objectives. To identify any relationship between the genes of the oxytocinergic pathway and psychosocial functioning in schizophrenia, i.e., the ability of…”
Get full text

Supportive evidence for the association between the T102C 5-HTR2A gene polymorphism and schizophrenia: A large-scale case–control and family-based study by Golimbet, V.E, Lavrushina, O.M, Kaleda, V.G, Abramova, L.I, Lezheiko, T.V

“…Abstract Serotonin type 2A receptors (5-HTR2A) have long been implicated in schizophrenia pathology. A decreased number of these receptors were found in…”
Get full text

Genetic Polymorphism of Cytokines IL-1β, IL-4, and TNF-α as a Factor Modifying the Influence of Adverse Childhood Experiences on the Symptoms of Schizophrenia by Alfimova, M. V., Korovaitseva, G. I., Gabaeva, M. V., Plakunova, V. V., Lezheiko, T. V., Golimbet, V. E.

“…Objectives . Working from the hypothesis that activation of the immune system is one of the mechanisms whereby early environmental factors influence the onset…”
Get full text

Studies of the Association of Genetic Polymorphism C677T in the Methylenetetrahydrofolate Reductase Gene with Symptom Severity in Schizophrenia Patients by Korovaitseva, G. I., Gabaeva, M. V., Golimbet, V. E.

“…Objective. To study the association of the C677T polymorphism of the MTHFR gene with the risk of developing schizophrenia in a large cohort including patients…”
Get full text

Copy number variations of satellite III (1q12) and ribosomal repeats in health and schizophrenia by Ershova, E.S., Malinovskaya, E.M., Golimbet, V.E., Lezheiko, T.V., Zakharova, N.V., Shmarina, G.V., Veiko, R.V., Umriukhin, P.E., Kostyuk, G.P., Kutsev, S.I., Izhevskaya, V.L., Veiko, N.N., Kostyuk, S.V.

“…Earlier we studied the copy number variations (CNVs) of ribosomal repeat (rDNA) and the satellite III fragment (1q12) (f-SatIII) in the cells of schizophrenia…”
Get full text

Prognostication of Functional Outcomes of Schizophrenia Using a Multigene Panel by Golubev, S. A., Lezheiko, T. V., Korovaitseva, G. I., Gabaeva, M. V., Kolesina, N. Yu, Kaleda, V. G., Golimbet, V. E.

“…Objectives. To compare groups of schizophrenia patients with different levels of functional outcomes and different frequencies of risk variants at polymorphic…”
Get full text

Association of the rs1344706 Polymorphism of the ZNF804A Gene with Induced EEG Rhythm Changes during Visual Perception of Verbal Stimuli in Healthy and Schizophrenic Subjects by Garakh, Zh. V., Golimbet, V. E., Larionova, E. V., Lezheiko, T. V., Strelets, V. B., Zaytseva, Yu. S.

“…The association of the rs1344706 polymorphism of the ZNF804A gene with EEG rhythm synchronization/ desynchronization parameters during the visual perception of…”
Get full text

A monogenic model of schizophrenia: a shift in paradigms by Golimbet, V E

“…Advanced genome technologies, including genome-wide association studies, next generation sequencing analysis, whole exome sequencing, encourage the development…”
Get more information

Methylation of the Reelin Gene Promoter in Peripheral Blood and Its Relationship with the Cognitive Function of Schizophrenia Patients by Alfimova, M. V., Kondratiev, N. V., Golov, A. K., Golimbet, V. E.

“…—There is a decrease in the expression of the reelin gene ( RELN ) in the brain of schizophrenia patients, which can underlie observed cognitive abnormalities…”
Get full text