Search Results - "Goldwater, R"

Proarrhythmic Safety of Repeat Doses of Mirabegron in Healthy Subjects: A Randomized, Double-Blind, Placebo-, and Active-Controlled Thorough QT Study by Malik, M, van Gelderen, E M, Lee, J H, Kowalski, D L, Yen, M, Goldwater, R, Mujais, S K, Schaddelee, M P, de Koning, P, Kaibara, A, Moy, S S, Keirns, J J

“…Potential effects of the selective β3‐adrenoceptor agonist mirabegron on cardiac repolarization were studied in healthy subjects. The four‐arm, parallel,…”
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A Phase 1, Randomized Ascending Single‐Dose Study of Antagonist Anti‐Human CD40 ASKP1240 in Healthy Subjects by Goldwater, R., Keirns, J., Blahunka, P., First, R., Sawamoto, T., Zhang, W., Kowalski, D., Kaibara, A., Holman, J.

“…This first‐in‐human, phase I study evaluated the safety, tolerability, pharmacokinetic and pharmacodynamic profile of ASKP1240 in healthy subjects. Twelve…”
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Epinephrine 0.3 mg Bioavailability Following a Single Injection with a Novel Epinephrine Auto-injector, e-cue™, in Healthy Adults, with Reference to a Single Injection using EpiPen® 0.3 mg by Edwards, E.S, Gunn, R, Simons, E.F, Carr, K, Chinchilli, V.M, Painter, G, Goldwater, R

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AZD3293 A novel BACE1 inhibitor: safety, tolerability, and effects on plasma and CSF Aβ peptides following single- and multiple-dose administration by Alexander, Robert, Budd, S, Russell, M, Kugler, A, Cebers, G, Ye, N, Olsson, T, Burdette, D, Maltby, J, Paraskos, J, Elsby, K, Han, D, Goldwater, R, Ereshefsky, L

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The Governor’s Wellmobile: Maryland’s Mobile Primary Care Clinic by Heller, Barbara R, Goldwater, Marilyn R

“…This article describes the development and implementation of the Governor’s Wellmobile program. Designed to increase access to community-based health care for…”
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Acid suppression in healthy subjects following lansoprazole or pantoprazole by Huang, J.‐Q., Goldwater, D. R., Thomson, A. B. R., Appelman, S. A., Sridhar, S., James, C. F., Chiu, Y.‐L., Pilmer, B. L., Keith, R. G., Hunt, R. H.

“…Aim: To compare the effect of lansoprazole, 30 mg once daily, with that of pantoprazole, 40 mg once daily, for the inhibition of gastric acid secretion…”
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D21 ASTHMA TREATMENT: GLUCOCORTICOIDS, BIOLOGICALS AND BEYOND:A Randomized, Double-Blinded, Placebo-Controlled, Ascending Dose Study Of The Safety, Tolerability, And Pharmacokinetics Of Xmab®7195 by Gershman, A, Goldwater, R, Foster, P

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Lack of a pharmacokinetic interaction between lansoprazole or pantoprazole and theophylline by PAN, W. J, GOLDWATER, D. R, ZHANG, Y, PILMER, B. L, HUNT, R. H

“…Aim: To study the potential pharmacokinetic interaction between lansoprazole or pantoprazole and theophylline at steady state. Methods: Theophylline 200 mg…”
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D94 ADVANCES IN CYSTIC FIBROSIS AND NON-CYSTIC FIBROSIS BRONCHIECTASIS: Enac Inhibitor Azd5634 First In Human Trial Reveals Promising Clinical Profile For The Treatment Of Cystic Fibrosis by Gardiner, P, Malmgren, A, Ersdal, E, Goldwater, R, Patel, N

“…In cystic fibrosis (CF), ENaC hyperactivity contributes to depletion in epithelial ASL resulting in reduced mucociliary clearance, recurrent infections and…”
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SAT-285 - Tolerabilityand kinetics of SYNB1020 in a Phase 1, first-in-Human, healthy adult volunteer study by Puurunen, M., Denney, W.S., Blankstein, L., Goldwater, R., Parsons, T., Millet, Y., Kurtz, C., Brennan, A.

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Tolerabilityand kinetics of SYNB1020 in a Phase 1, first-in-Human, healthy adult volunteer study by Puurunen, M., Denney, W.S., Blankstein, L., Goldwater, R., Parsons, T., Millet, Y., Kurtz, C., Brennan, A.

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AZD3293: Pharmacokinetic and Pharmacodynamic Effects in Healthy Subjects and Patients with Alzheimer's Disease by Cebers, Gvido, Alexander, Robert C, Haeberlein, Samantha Budd, Han, David, Goldwater, Ronald, Ereshefsky, Larry, Olsson, Tina, Ye, Naidong, Rosen, Laura, Russell, Muir, Maltby, Justine, Eketjäll, Susanna, Kugler, Alan R

“…AZD3293 (LY3314814) is a promising new potentially disease-modifying BACE1 (β-secretase) inhibitor in Phase III clinical development for the treatment of…”
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A single blind, placebo controlled, across groups dose escalation study of the safety, tolerability, pharmacokinetics and pharmacodynamics of the melatonin analog β-methyl-6-chloromelatonin by Mulchahey, J.J, Goldwater, D.R, Zemlan, F.P

“…Clinical investigation of melatonin agonists has been hampered by side effects such as hypothermia, hypotension and bradycardia. The availability of a…”
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Phase 1, randomized, parallel, placebo-controlled, safety, tolerance and pharmacokinetic study of multiple dose of IY-81149 in fasting male volunteers by GOLDWATER, R, BOILEAU, F, LEE, S, CHUNG, G, KIM, D, CHO, K

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Maribavir Is Bioequivalent in Fed and Fasted Healthy Subjects by Goldwater, R, Johnson, J, Schumacher, M, Villano, S

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A preliminary study of emotional intelligence, empathy and exam performance in first year medical students by Austin, Elizabeth J., Evans, Phillip, Goldwater, Ruth, Potter, Victoria

“…A group of 156 first year medical students completed measures of emotional intelligence (EI) and physician empathy, and a scale assessing their feelings about…”
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Epinephrine 0.3 mg Bioavailability Following a Single Injection with a Novel Epinephrine Auto-injector in Healthy Adults, with Reference to a Single Injection using EpiPen by Edwards, E., Gunn, R., Simons, E., Carr, C., Chinchilli, V.M., Painter, G., Goldwater, R.

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A Phase I study evaluating the effect of age and weight on the pharmacokinetics of an injectable formulation of diclofenac solubilized with hydroxypropyl-β-cyclodextrin by Goldwater, Ronald, Kramer, William G, Hamilton, Douglas A, Lang, Eric, Wang, Jianyuan, Madden, Donna E, Lacouture, Peter G, Ramaiya, Atulkumar, Carr, Daniel B

“…The analgesic and opioid-sparing effects of nonsteroidal anti-inflammatory drugs can be beneficial in postoperative populations. Hydroxypropyl-β-cyclodextrin…”
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A comparative pharmacodynamic study of IY-81149 versus omeprazole in patients with gastroesophageal reflux disease by Periclou, Antonia P., Goldwater, Ronald, Lee, Seung Mok, Park, Dong Woo, Kim, Dong Yeon, Do Cho, Kil, Boileau, François, Jung, Won Tae

“…Objective To evaluate and compare the pharmacodynamic effects of IY‐81149 and omeprazole on gastric pH in patients with gastroesophageal reflux disease…”
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Toward the maieutic management of business systems by Goldwater, R., Berens, H., Jonath, F., Vasquez, B., Jonath, A.

“…In response to the shortening product life cycle, we have increased parallelism in all aspects of our work in the microelectronics industry. In order to…”
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