Search Results - "Goldstein, S D"

Orthostatic hypotension from sympathetic denervation in Parkinson's disease by GOLDSTEIN, D. S, HOLMES, C. S, DENDI, R, BRUCE, S. R, LI, S.-T

“…Patients with PD often have signs or symptoms of autonomic failure, including orthostatic hypotension. Cardiac sympathetic denervation occurs frequently in PD,…”
Get full text

Plasma levels of catechols and metanephrines in neurogenic orthostatic hypotension by GOLDSTEIN, D. S, HOLMES, C, SHARABI, Y, BRENTZEL, S, EISENHOFER, G

“…Neurogenic orthostatic hypotension (NOH) usually results from deficient release of the sympathetic neurotransmitter norepinephrine (NE) when the patient stands…”
Get full text

Distinct gene expression profiles in norepinephrine- and epinephrine-producing hereditary and sporadic pheochromocytomas: activation of hypoxia-driven angiogenic pathways in von Hippel–Lindau syndrome by Eisenhofer, G, Huynh, T-T, Pacak, K, Brouwers, F M, Walther, M M, Linehan, W M, Munson, P J, Mannelli, M, Goldstein, D S, Elkahloun, A G

“…Pheochromocytomas in von Hippel–Lindau (VHL) syndrome produce exclusively norepinephrine, whereas those in multiple endocrine neoplasia type 2 (MEN 2) produce…”
Get full text

Clickers in the Classroom: Using Classroom Response Systems to Increase Student Learning by Goldstein, David S, Wallis, Peter D, Rhem, James

“…With classroom response systems (or CRSs, also known as Student Response Systems, Individual Response Systems, or, informally, clickers ) in use in higher…”
Get full text

Cardiac sympathetic denervation in Parkinson disease by GOLDSTEIN, D. S, HOLMES, C, LI, S.-T, BRUCE, S, METMAN, L. V, CANNON, R. O

“…In Parkinson disease, orthostatic hypotension can result from L-dopa treatment or from sympathetic neurocirculatory failure. The latter is detected by abnormal…”
Get full text

Recent advances in genetics, diagnosis, localization, and treatment of pheochromocytoma by PACAK, Karel, LINEHAN, W. Marston, EISENHOFER, Graeme, WALTHER, Mcclellan M, GOLDSTEIN, David S

“…Pheochromocytoma is a rare but important tumor of chromaffin cells that is frequently considered in the evaluation of hypertension, arrhythmias, or panic…”
Get full text

Neurocirculatory and nigrostriatal abnormalities in Parkinson disease from LRRK2 mutation by GOLDSTEIN, D. S, IMRICH, R, PECKHAM, E, HOLMES, C, LOPEZ, G, CREWS, C, HARDY, J, SINGLETON, A, HALLETT, M

“…Patients with Parkinson disease (PD) often have cardiac sympathetic denervation and failure of neurocirculatory regulation by baroreflexes. Familial PD caused…”
Get full text

Guanylyl Cyclase C is a Selective Marker for Metastatic Colorectal Tumors in Human Extraintestinal Tissues by Carrithers, S. L., Barber, M. T., Biswas, S., Parkinson, S. J., Park, P. K., Goldstein, S. D., Waldman, S. A.

“…Guanylyl cyclase C (GCC) has been detected only in intestinal mucosa and colon carcinoma cells of placental mammals. However, this receptor has been identified…”
Get full text

Plasma Normetanephrine and Metanephrine for Detecting Pheochromocytoma in von Hippel–Lindau Disease and Multiple Endocrine Neoplasia Type 2 by Eisenhofer, Graeme, Lenders, Jacques W.M, Linehan, W. Marston, Walther, McClellan M, Goldstein, David S, Keiser, Harry R

“…Von Hippel–Lindau disease and multiple endocrine neoplasia type 2 (MEN-2) are multisystem neoplastic disorders, inherited in an autosomal dominant fashion,…”
Get full text

Relative contribution of core and cutaneous temperatures to thermal comfort and autonomic responses in humans by Frank, Steven M, Raja, Srinivasa N, Bulcao, Christian F, Goldstein, David S

“…1  Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287; 2  School of Medicine, McGill…”
Get full text

Catechols in post-mortem brain of patients with Parkinson disease by Goldstein, D. S., Sullivan, P., Holmes, C., Kopin, I. J., Basile, M. J., Mash, D. C.

“…Background:  Dihydroxyphenylacetaldehyde (DOPAL), a cytotoxic metabolite of dopamine, is the focus of the ‘catecholaldehyde hypothesis’ about the pathogenesis…”
Get full text

Sympathetic Cardioneuropathy in Dysautonomias by Goldstein, David S, Holmes, Courtney, Cannon, Richard O, Eisenhofer, Graeme, Kopin, Irwin J

“…Dysautonomias, derangements of sympathetic or parasympathetic nervous system function, are seen fairly often in neurology and cardiology. Autonomic…”
Get full text

Comparison of Monoamine Oxidase Inhibitors in Decreasing Production of the Autotoxic Dopamine Metabolite 3,4-Dihydroxyphenylacetaldehyde in PC12 Cells by Goldstein, David S, Jinsmaa, Yunden, Sullivan, Patti, Holmes, Courtney, Kopin, Irwin J, Sharabi, Yehonatan

“…According to the catecholaldehyde hypothesis, the toxic dopamine metabolite 3,4-dihydroxyphenylacetaldehyde (DOPAL) contributes to the loss of nigrostriatal…”
Get more information

Cardiac sympathetic nerve function in congestive heart failure by EISENHOFER, G, FRIBERG, P, RUNDQVIST, B, QUYYUMI, A. A, LAMBERT, G, KAYE, D. M, KOPIN, I. J, GOLDSTEIN, D. S, ESLER, M. D

“…Increased availability of norepinephrine (NE) for activation of cardiac adrenoceptors (increased cardiac adrenergic drive) and depletion of myocardial NE…”
Get full text

Clinical and therapeutic observations in aromatic L-amino acid decarboxylase deficiency by SWOBODA, K. J, HYLAND, K, GOLDSTEIN, D. S, KUBAN, K. C. K, ARNOLD, L. A, HOLMES, C. S, LEVY, H. L

“…To elucidate the phenotype in aromatic L-amino acid decarboxylase (AADC) deficiency, a rare autosomal recessive disorder of neurotransmitter synthesis, and…”
Get full text

Norepinephrine Spillover from Human Adipose Tissue before and after a 72-Hour Fast by Patel, J. N., Coppack, S. W., Goldstein, D. S., Miles, J. M., Eisenhofer, G.

“…Adipose tissue lipolysis is at least in part stimulated by the sympathetic nervous system (SNS). Although there is a generalized decrease in SNS activity with…”
Get full text

Sources and Physiological Significance of Plasma Dopamine Sulfate by Goldstein, David S, Swoboda, Kathryn J, Miles, John M, Coppack, Simon W, Aneman, Anders, Holmes, Courtney, Lamensdorf, Isaac, Eisenhofer, Graeme

“…Dopamine in the circulation occurs mainly as dopamine sulfate, the sources and physiological significance of which have been obscure. In this study, plasma…”
Get full text

Influence of cigarette smoking on human autonomic function by Niedermaier, O. N., Smith, M. L., Beightol, L. A., Zukowska-Grojec, Z., Goldstein, D. S., Eckberg, D. L.

“…BACKGROUND. Although cigarette smoking is known to lead to widespread augmentation of sympathetic nervous system activity, little is known about the effects of…”
Get full text

Endogenous serotonin stimulates striatal dopamine release in conscious rats by Yadid, G, Pacak, K, Kopin, I J, Goldstein, D S

“…Serotonin (5-HT) and dopamine (DA) are established neurotransmitters in the brain. This study examined whether, in conscious, free-moving rats, increased…”
Get more information

Use of guanylyl cyclase C for detecting micrometastases in lymph nodes of patients with colon cancer by Waldman, S A, Cagir, B, Rakinic, J, Fry, R D, Goldstein, S D, Isenberg, G, Barber, M, Biswas, S, Minimo, C, Palazzo, J, Park, P K, Weinberg, D

“…Guanylyl cyclase C appears to be expressed only in colorectal cancer cells in extraintestinal tissues. Thus, guanylyl cyclase C may be useful as a marker to…”
Get more information