Search Results - "Goldstein, M A"
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Building a brain in the gut: development of the enteric nervous system
Published in Clinical genetics (01-04-2013)“…The enteric nervous system (ENS), the intrinsic innervation of the gastrointestinal tract, is an essential component of the gut neuromusculature and controls…”
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iPTF17cw: An Engine-driven Supernova Candidate Discovered Independent of a Gamma-Ray Trigger
Published in The Astrophysical journal (20-09-2017)“…We present the discovery, classification, and radio-to-X-ray follow-up observations of iPTF17cw, a broad-lined (BL) type Ic supernova (SN) discovered by the…”
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3
Endoscopic delivery of enteric neural stem cells to treat Hirschsprung disease
Published in Neurogastroenterology and motility (01-10-2015)“…Background Transplantation of enteric neural stem cells (ENSC) holds promise as a potential therapy for enteric neuropathies, including Hirschsprung disease…”
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Nestin‐expressing cells in the gut give rise to enteric neurons and glial cells
Published in Neurogastroenterology and motility (01-01-2013)“…Background Neuronal stem cells (NSCs) are promising for neurointestinal disease therapy. Although NSCs have been isolated from intestinal musclularis, their…”
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Stromal inactivation of BMPRII leads to colorectal epithelial overgrowth and polyp formation
Published in Oncogene (14-02-2008)“…Stromal–epithelial interactions play a central role in development and tumorigenesis. Bone morphogenetic protein (BMP) signaling in the intestine is involved…”
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Analysis of gastrointestinal physiology using a novel intestinal transit assay in zebrafish
Published in Neurogastroenterology and motility (01-03-2009)“…Gastrointestinal function depends upon coordinated contractions to mix and propel food through the gut. Deregulation of these contractions leads to alterations…”
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Association of MC1R Variants and Host Phenotypes With Melanoma Risk in CDKN2A Mutation Carriers: A GenoMEL Study
Published in JNCI : Journal of the National Cancer Institute (20-10-2010)“…Background Carrying the cyclin-dependent kinase inhibitor 2A (CDKN2A) germline mutations is associated with a high risk for melanoma. Penetrance of CDKN2A…”
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Relationship between postprandial metabolomics and colon motility in children with constipation
Published in Neurogastroenterology and motility (01-05-2013)“…Background The metabolic pathways associated with colonic motility are unknown. To identify potential metabolic targets for treatment of constipation, we…”
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Adverse effects of trichothiodystrophy DNA repair and transcription gene disorder on human fetal development
Published in Clinical genetics (01-04-2010)“…Moslehi R, Signore C, Tamura D, Mills JL, DiGiovanna JJ, Tucker MA, Troendle J, Ueda T, Boyle J, Khan SG, Oh K‐S, Goldstein AM, Kraemer KH. Adverse effects of…”
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Epstein-Barr virus microRNAs and lung cancer
Published in British journal of cancer (12-07-2011)“…Background: We conducted the first analysis of viral microRNAs (miRNAs) in lung cancer, with a focus on Epstein–Barr virus (EBV). Methods: We evaluated viral…”
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Full-field optical coherence microscopy is a novel technique for imaging enteric ganglia in the gastrointestinal tract
Published in Neurogastroenterology and motility (01-12-2012)“…Background Noninvasive methods are needed to improve the diagnosis of enteric neuropathies. Full‐field optical coherence microscopy (FFOCM) is a novel optical…”
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Structural and functional brain asymmetries in human situs inversus totalis
Published in Neurology (12-10-1999)“…To determine whether individuals with situs inversus totalis (SI), a condition in which there is a mirror-image reversal of asymmetric visceral organs, have…”
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Correlates of anti-EBV EBNA1 IgA positivity among unaffected relatives from nasopharyngeal carcinoma multiplex families
Published in British journal of cancer (03-01-2012)“…Background: To determine whether non-viral nasopharyngeal carcinoma (NPC) risk factors might be associated with (and mediated through) Epstein–Barr virus (EBV)…”
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Guidelines for the management of postoperative obstructive symptoms in children with Hirschsprung disease
Published in Pediatric Surgery International (01-05-2017)“…Although most children with Hirschsprung disease ultimately do well, many experience a variety of ongoing problems after pull-through surgery. The most common…”
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Comprehensive analysis of CDKN2A (p16INK4A/p14ARF) and CDKN2B genes in 53 melanoma index cases considered to be at heightened risk of melanoma
Published in Journal of medical genetics (01-01-2006)“…Objective: Comprehensive analysis of the 9p21 locus including the CDKN2A, ARF, and CDKN2B genes in 53 individuals from melanoma index cases considered to be at…”
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CDKN2A mutations and melanoma risk in the Icelandic population
Published in Journal of medical genetics (01-05-2008)“…Germline CDKN2A mutations have been observed in 20-40% of high risk, melanoma prone families; however, little is known about their prevalence in population…”
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Genotype–Phenotype Relationships in U.S. Melanoma-Prone Families With CDKN2A and CDK4 Mutations
Published in JNCI : Journal of the National Cancer Institute (21-06-2000)“…Background: Two genes have been implicated in the development of cutaneous malignant melanoma (CMM). CDK4 (the gene encoding cyclin-dependent kinase 4, an…”
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Genetic susceptibility in familial melanoma from northeastern Italy
Published in Journal of medical genetics (01-07-2004)“…Table 1 Family characteristics No CMM in family No families Mean age at CMM diagnosis* Families with Other cancers in melanoma cases No families by region MPM…”
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Epidemiologic and Genetic Approaches in the Study of Gene-Environment Interaction: an Overview of Available Methods
Published in Epidemiologic reviews (1998)“…Gene-environment studies are motivated by different situations including: 1) The detection of major genes that do not have estimated lifetime risks that reach…”
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CDKN2A Mutations in Multiple Primary Melanomas
Published in The New England journal of medicine (26-03-1998)“…Some patients with cancer have one or more subsequent primary tumors of the same histologic subtype. This phenomenon can be explained by the long-term exposure…”
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