Search Results - "Goldstein, Darlene R"

Meta-analysis of gene expression profiles in breast cancer: toward a unified understanding of breast cancer subtyping and prognosis signatures by Wirapati, Pratyaksha, Sotiriou, Christos, Kunkel, Susanne, Farmer, Pierre, Pradervand, Sylvain, Haibe-Kains, Benjamin, Desmedt, Christine, Ignatiadis, Michail, Sengstag, Thierry, Schütz, Frédéric, Goldstein, Darlene R, Piccart, Martine, Delorenzi, Mauro

“…Breast cancer subtyping and prognosis have been studied extensively by gene expression profiling, resulting in disparate signatures with little overlap in…”
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MAP kinase phosphatase 1 (MKP-1/DUSP1) is neuroprotective in Huntington's disease via additive effects of JNK and p38 inhibition by Taylor, David M, Moser, Roger, Régulier, Etienne, Breuillaud, Lionel, Dixon, Meredith, Beesen, Ayshe Ana, Elliston, Linda, Silva Santos, Mariana de Fatima, Kim, Jinho, Jones, Lesley, Goldstein, Darlene R, Ferrante, Robert J, Luthi-Carter, Ruth

“…We previously demonstrated that sodium butyrate is neuroprotective in Huntington's disease (HD) mice and that this therapeutic effect is associated with…”
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Serum antiglycan antibody detection of nonmucinous ovarian cancers by using a printed glycan array by Jacob, Francis, Goldstein, Darlene R., Bovin, Nicolai V., Pochechueva, Tatiana, Spengler, Marianne, Caduff, Rosemarie, Fink, Daniel, Vuskovic, Marko I., Huflejt, Margaret E., Heinzelmann-Schwarz, Viola

“…Epithelial ovarian cancer has the highest mortality rate among gynecological cancers. Altered glycosylation is associated with oncogenic transformation…”
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Selecting control genes for RT-QPCR using public microarray data by Popovici, Vlad, Goldstein, Darlene R, Antonov, Janine, Jaggi, Rolf, Delorenzi, Mauro, Wirapati, Pratyaksha

“…Gene expression analysis has emerged as a major biological research area, with real-time quantitative reverse transcription PCR (RT-QPCR) being one of the most…”
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Partition resampling and extrapolation averaging: approximation methods for quantifying gene expression in large numbers of short oligonucleotide arrays by GOLDSTEIN, Darlene R

“…Motivation: Studies of gene expression using high-density short oligonucleotide arrays have become a standard in a variety of biological contexts. Of the…”
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Comprehensive analysis of Arabidopsis expression level polymorphisms with simple inheritance by Goldstein, Darlene R, Hardtke, Christian S, Weber, Johann, Nussbaumer, Cindy, Harshman, Keith, Plantegenet, Stephanie, Weigel, Detlef, Zeller, Georg, Thomas, Jérôme

“…In Arabidopsis thaliana , gene expression level polymorphisms (ELPs) between natural accessions that exhibit simple, single locus inheritance are promising…”
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Assessment of the relationship between pre-chip and post-chip quality measures for Affymetrix GeneChip expression data by Jones, Lesley, Goldstein, Darlene R, Hughes, Gareth, Strand, Andrew D, Collin, Francois, Dunnett, Stephen B, Kooperberg, Charles, Aragaki, Aaron, Olson, James M, Augood, Sarah J, Faull, Richard L M, Luthi-Carter, Ruth, Moskvina, Valentina, Hodges, Angela K

“…Gene expression microarray experiments are expensive to conduct and guidelines for acceptable quality control at intermediate steps before and after the…”
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Automatic module selection from several microarray gene expression studies by Zollinger, Alix, Davison, Anthony C, Goldstein, Darlene R

“…SUMMARY Independence of genes is commonly but incorrectly assumed in microarray data analysis; rather, genes are activated in co-regulated sets referred to as…”
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Regional and cellular gene expression changes in human Huntington's disease brain by Hodges, Angela, Strand, Andrew D., Aragaki, Aaron K., Kuhn, Alexandre, Sengstag, Thierry, Hughes, Gareth, Elliston, Lyn A., Hartog, Cathy, Goldstein, Darlene R., Thu, Doris, Hollingsworth, Zane R., Collin, Francois, Synek, Beth, Holmans, Peter A., Young, Anne B., Wexler, Nancy S., Delorenzi, Mauro, Kooperberg, Charles, Augood, Sarah J., Faull, Richard L.M., Olson, James M., Jones, Lesley, Luthi-Carter, Ruth

“…Huntington's disease (HD) pathology is well understood at a histological level but a comprehensive molecular analysis of the effect of the disease in the human…”
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Mutant huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant huntingtin length or wild-type huntingtin dosage by Kuhn, Alexandre, Goldstein, Darlene R., Hodges, Angela, Strand, Andrew D., Sengstag, Thierry, Kooperberg, Charles, Becanovic, Kristina, Pouladi, Mahmoud A., Sathasivam, Kirupa, Cha, Jang-Ho J., Hannan, Anthony J., Hayden, Michael R., Leavitt, Blair R., Dunnett, Stephen B., Ferrante, Robert J., Albin, Roger, Shelbourne, Peggy, Delorenzi, Mauro, Augood, Sarah J., Faull, Richard L.M., Olson, James M., Bates, Gillian P., Jones, Lesley, Luthi-Carter, Ruth

“…To test the hypotheses that mutant huntingtin protein length and wild-type huntingtin dosage have important effects on disease-related transcriptional…”
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Meta-Analysis of Microarray Data Identifies GAS6 Expression as an Independent Predictor of Poor Survival in Ovarian Cancer by Heinzelmann, Viola, Fink, Daniel, Caduff, Rosmarie, Jacob, Francis, Leboucq, Alix, Tse, Brian W. C., Buehler, Michelle, Goldstein, Darlene R.

“…Seeking new biomarkers for epithelial ovarian cancer, the fifth most common cause of death from all cancers in women and the leading cause of death from…”
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Reliable gene expression measurements from degraded RNA by quantitative real-time PCR depend on short amplicons and a proper normalization by ANTONOV, Janine, GOLDSTEIN, Darlene R, OBERLI, Andrea, BALTZER, Anna, PIROTTA, Marco, FLEISCHMANN, Achim, ALTERMATT, Hails J, JAGGI, Rolf

“…Quantitative reverse transcriptase real-time PCR (QRT-PCR) is a robust method to quantitate RNA abundance. The procedure is highly sensitive and reproducible…”
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Meta-analysis of incomplete microarray studies by Zollinger, Alix, Davison, Anthony C, Goldstein, Darlene R

“…Meta-analysis of microarray studies to produce an overall gene list is relatively straightforward when complete data are available. When some studies lack…”
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Comparison of printed glycan array, suspension array and ELISA in the detection of human anti-glycan antibodies by Pochechueva, Tatiana, Jacob, Francis, Goldstein, Darlene R., Huflejt, Margaret E., Chinarev, Alexander, Caduff, Rosemarie, Fink, Daniel, Hacker, Neville, Bovin, Nicolai V., Heinzelmann-Schwarz, Viola

“…Anti-glycan antibodies represent a vast and yet insufficiently investigated subpopulation of naturally occurring and adaptive antibodies in humans. Recently, a…”
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Modulation of nucleosome dynamics in Huntington's disease by Stack, Edward C., Del Signore, Steven J., Luthi-Carter, Ruth, Soh, Byoung Y., Goldstein, Darlene R., Matson, Samantha, Goodrich, Sarah, Markey, Angela L., Cormier, Kerry, Hagerty, Sean W., Smith, Karen, Ryu, Hoon, Ferrante, Robert J.

“…Transcriptional dysregulation and aberrant chromatin remodeling are central features in the pathology of Huntington's disease (HD). In order to more fully…”
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Mechanisms Regulating the Proliferative Potential of Human CD8+ T Lymphocytes Overexpressing Telomerase by Menzel, Olivier, Migliaccio, Marco, Goldstein, Darlene R, Dahoun, Sophie, Delorenzi, Mauro, Rufer, Nathalie

“…In human somatic cells, including T lymphocytes, telomeres progressively shorten with each cell division, eventually leading to a state of cellular senescence…”
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Environmental Enrichment Reduces Neuronal Intranuclear Inclusion Load But Has No Effect on Messenger RNA Expression in a Mouse Model of Huntington Disease by Benn, Caroline L, Luthi-Carter, Ruth, Kuhn, Alexandre, Sadri-Vakili, Ghazaleh, Blankson, Kwabena L, Dalai, Sudeb C, Goldstein, Darlene R, Spires, Tara L, Pritchard, Joel, Olson, James M, van Dellen, Anton, Hannan, Anthony J, Cha, Jang-Ho J

“…Huntington disease (HD) is a fatal neurodegenerative disease with no effective treatment. In the R6/1 mouse model of HD, environmental enrichment delays the…”
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Interaction of bifidobacteria with Caco-2 cells—adhesion and impact on expression profiles by Riedel, Christian U., Foata, Francis, Goldstein, Darlene R., Blum, Stephanie, Eikmanns, Bernhard J.

“…The aim of the present study was to study different strains of bifidobacteria for adhesion to Caco-2 intestinal epithelial cells (IECs) and to test for the…”
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A Laplace mixture model for identification of differential expression in microarray experiments by Bhowmick, Debjani, Davison, A C, Goldstein, Darlene R, Ruffieux, Yann

“…Microarrays have become an important tool for studying the molecular basis of complex disease traits and fundamental biological processes. A common purpose of…”
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Household smoking behavior and ETS exposure among children with asthma in low-income, minority households by Berman, Barbara A, Wong, Glenn C, Bastani, Roshan, Hoang, Tuyen, Jones, Craig, Goldstein, Darlene R, Bernert, J.Thomas, Hammond, Katherine S, Tashkin, Donald, Lewis, Mary Ann

“…Environmental tobacco smoke (ETS) exposure was measured among 242 children with asthma who live in homes where at least one person smokes. Subjects were…”
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