Search Results - "Goldstein, D B"

Differing opinions about natural gas drilling in two adjacent counties with different levels of drilling activity by Kriesky, J., Goldstein, B.D., Zell, K., Beach, S.

“…The pace of development of shale gas plays varies greatly among US states and globally. Through analysis of telephone survey responses, we explore support for…”
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Fetal exome sequencing for isolated increased nuchal translucency: should we be doing it? by Mellis, R, Eberhardt, RY, Hamilton, SJ, McMullan, DJ, Kilby, MD, Maher, ER, Hurles, ME, Giordano, JL, Aggarwal, V, Goldstein, DB, Wapner, RJ, Chitty, LS

“…Objective To evaluate the utility of prenatal exome sequencing (ES) for isolated increased nuchal translucency (NT) and to investigate factors that increase…”
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A non-equilibrium surface reservoir approach for hybrid DSMC/Navier–Stokes particle generation by Stephani, K.A., Goldstein, D.B., Varghese, P.L.

“…An approach for the generation of particles at a hybrid Navier–Stokes/DSMC interface is presented for simple gases and gas mixtures with internal degrees of…”
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ABCB1/MDR1 gene determines susceptibility and phenotype in ulcerative colitis: discrimination of critical variants using a gene-wide haplotype tagging approach by Ho, G.-T., Soranzo, N., Nimmo, E.R., Tenesa, A., Goldstein, D.B., Satsangi, J.

“…Several lines of evidence suggest a role for the multidrug resistance gene (ABCB1/MDR1) and its product, P-glycoprotein 170, in the pathogenesis of…”
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Practical considerations in the clinical application of whole-exome sequencing by Shashi, V., McConkie-Rosell, A., Schoch, K., Kasturi, V., Rehder, C., Jiang, Y.H., Goldstein, D.B., McDonald, M.T.

“…Despite the exciting advent of whole‐exome sequencing (WES) in medical genetics practices, the optimal interpretation of results requires further actions such…”
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Islands of linkage disequilibrium by Goldstein, David B

“…A detailed knowledge of patterns of linkage disequilibrium in human populations is widely seen as a prerequisite for effective population-based disease gene…”
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Monte Carlo solution of the Boltzmann equation via a discrete velocity model by Morris, A.B., Varghese, P.L., Goldstein, D.B.

“…A new discrete velocity scheme for solving the Boltzmann equation is described. Directly solving the Boltzmann equation is computationally expensive because,…”
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Launching Microsatellites: A Review of Mutation Processes and Methods of Phylogenetic Inference by Goldstein, D. B., Pollock, D. D.

“…A great deal of work remains to be done in evaluating how best to employ microsatellites in phylogeny reconstruction…”
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SLC1A4 mutations cause a novel disorder of intellectual disability, progressive microcephaly, spasticity and thin corpus callosum by Heimer, G., Marek-Yagel, D., Eyal, E., Barel, O., Oz Levi, D., Hoffmann, C., Ruzzo, E.K., Ganelin-Cohen, E., Lancet, D., Pras, E., Rechavi, G., Nissenkorn, A., Anikster, Y., Goldstein, D.B., Ben Zeev, B.

“…Two unrelated patients, presenting with significant global developmental delay, severe progressive microcephaly, seizures, spasticity and thin corpus callosum…”
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Genetic Absolute Dating Based on Microsatellites and the Origin of Modern Humans by Goldstein, D. B., Linares, A. Ruiz, Cavalli-Sforza, L. L., Feldman, M. W.

“…We introduce a new genetic distance for microsatellite loci, incorporating features of the stepwise mutation model, and test its performance on microsatellite…”
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The RBMX gene as a candidate for the Shashi X-linked intellectual disability syndrome by Shashi, V., Xie, P., Schoch, K., Goldstein, D.B., Howard, T.D., Berry, M.N., Schwartz, C.E., Cronin, K., Sliwa, S., Allen, A., Need, A.C.

“…A novel X‐linked intellectual disability (XLID) syndrome with moderate intellectual disability and distinguishing craniofacial dysmorphisms had been previously…”
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1-D DSMC simulation of Io's atmospheric collapse and reformation during and after eclipse by Moore, C.H., Goldstein, D.B., Varghese, P.L., Trafton, L.M., Stewart, B.

“…A one-dimensional Direct Simulation Monte Carlo (DSMC) model is used to examine the effects of a non-condensable species on Io's sulfur dioxide sublimation…”
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An Evaluation of Genetic Distances for Use With Microsatellite Loci by Goldstein, D. B, Linares, A. R, Cavalli-Sforza, L. L, Feldman, M. W

“…Mutations of alleles at microsatellite loci tend to result in alleles with repeat scores similar to those of the alleles from which they were derived…”
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Numerical modeling of ionian volcanic plumes with entrained particulates by Zhang, J., Goldstein, D.B., Varghese, P.L., Trafton, L., Moore, C., Miki, K.

“…Volcanic plumes on Jupiter's moon Io are modeled using the direct simulation Monte Carlo (DSMC) method. The modeled volcanic vent is interpreted as a “virtual”…”
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Guidelines for investigating causality of sequence variants in human disease by MacArthur, D. G., Manolio, T. A., Dimmock, D. P., Rehm, H. L., Shendure, J., Abecasis, G. R., Adams, D. R., Altman, R. B., Antonarakis, S. E., Ashley, E. A., Barrett, J. C., Biesecker, L. G., Conrad, D. F., Cooper, G. M., Cox, N. J., Daly, M. J., Gerstein, M. B., Goldstein, D. B., Hirschhorn, J. N., Leal, S. M., Pennacchio, L. A., Stamatoyannopoulos, J. A., Sunyaev, S. R., Valle, D., Voight, B. F., Winckler, W., Gunter, C.

“…Acceleration in discovery of rare genetic variants possibly linked with disease may mean an increased risk of false-positive reports of causality; this…”
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The Precautionary Principle Also Applies to Public Health Actions by Goldstein, Bernard D

“…The precautionary principle asserts that the burden of proof for potentially harmful actions by industry or government rests on the assurance of safety and…”
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No major role of common SV2A variation for predisposition or levetiracetam response in epilepsy by Lynch, J.M, Tate, S.K, Kinirons, P, Weale, M.E, Cavalleri, G.L, Depondt, C, Murphy, K, O’Rourke, D, Doherty, C.P, Shianna, K.V, Wood, N.W, Sander, J.W, Delanty, N, Goldstein, D.B, Sisodiya, S.M

“…Summary Levetiracetam (LEV), a newer antiepileptic drug (AED) useful for several epilepsy syndromes, binds to SV2A. Identifying genetic variants that influence…”
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The α-synuclein gene in multiple system atrophy by Ozawa, T, Healy, D G, Abou-Sleiman, P M, Ahmadi, K R, Quinn, N, Lees, A J, Shaw, K, Wullner, U, Berciano, J, Moller, J C, Kamm, C, Burk, K, Josephs, K A, Barone, P, Tolosa, E, Goldstein, D B, Wenning, G, Geser, F, Holton, J L, Gasser, T, Revesz, T, Wood, N W

“…Background: The formation of α-synuclein aggregates may be a critical event in the pathogenesis of multiple system atrophy (MSA). However, the role of this…”
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Genome scans and candidate gene approaches in the study of common diseases and variable drug responses by Goldstein, David B., Ahmadi, Kourosh R., Weale, Mike E., Wood, Nicholas W.

“…There is both tremendous enthusiasm and controversy surrounding genetic association studies. In this article we use new methods for representing variation in…”
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Quantitative genetic analysis of natural variation in body size in Drosophila melanogaster by Gockel, J, Robinson, S J W, Kennington, W J, Goldstein, D B, Partridge, L

“…Latitudinal, genetic variation in body size is a commonly observed phenomenon in many invertebrate species and is shaped by natural selection. In this study,…”
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