Search Results - "Goldstein, Alisa M."

A systematic review of the prevalence of germline pathogenic variants in patients with pancreatic cancer by Astiazaran-Symonds, Esteban, Goldstein, Alisa M.

“…The genetics of pancreatic ductal adenocarcinoma (PDAC) is complex with patients reported to harbor germline pathogenic variants (PVs) in many different genes…”
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Nested PCR Biases in Interpreting Microbial Community Structure in 16S rRNA Gene Sequence Datasets by Yu, Guoqin, Fadrosh, Doug, Goedert, James J, Ravel, Jacques, Goldstein, Alisa M

“…Sequencing of the PCR-amplified 16S rRNA gene has become a common approach to microbial community investigations in the fields of human health and…”
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Whole genome sequencing of skull-base chordoma reveals genomic alterations associated with recurrence and chordoma-specific survival by Bai, Jiwei, Shi, Jianxin, Li, Chuzhong, Wang, Shuai, Zhang, Tongwu, Hua, Xing, Zhu, Bin, Koka, Hela, Wu, Ho-Hsiang, Song, Lei, Wang, Difei, Wang, Mingyi, Zhou, Weiyin, Ballew, Bari J., Zhu, Bin, Hicks, Belynda, Mirabello, Lisa, Parry, Dilys M., Zhai, Yixuan, Li, Mingxuan, Du, Jiang, Wang, Junmei, Zhang, Shuheng, Liu, Qian, Zhao, Peng, Gui, Songbai, Goldstein, Alisa M., Zhang, Yazhuo, Yang, Xiaohong R.

“…Chordoma is a rare bone tumor with an unknown etiology and high recurrence rate. Here we conduct whole genome sequencing of 80 skull-base chordomas and…”
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Integrated analysis of genome-wide miRNAs and targeted gene expression in esophageal squamous cell carcinoma (ESCC) and relation to prognosis by Yang, Howard, Su, Hua, Hu, Nan, Wang, Chaoyu, Wang, Lemin, Giffen, Carol, Goldstein, Alisa M, Lee, Maxwell P, Taylor, Philip R

“…Esophageal squamous cell carcinoma (ESCC) is a leading cause of cancer death worldwide and in China. We know miRNAs influence gene expression in tumorigenesis,…”
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Molecular Characterization of the Human Stomach Microbiota in Gastric Cancer Patients by Yu, Guoqin, Torres, Javier, Hu, Nan, Medrano-Guzman, Rafael, Herrera-Goepfert, Roberto, Humphrys, Michael S, Wang, Lemin, Wang, Chaoyu, Ding, Ti, Ravel, Jacques, Taylor, Philip R, Abnet, Christian C, Goldstein, Alisa M

“…( ) is the primary cause of gastric cancer but we know little of its relative abundance and other microbes in the stomach, especially at the time of gastric…”
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Index‐based dietary patterns and risk of incident hepatocellular carcinoma and mortality from chronic liver disease in a prospective study by Li, Wen‐Qing, Park, Yikyung, McGlynn, Katherine A., Hollenbeck, Albert R., Taylor, Philip R., Goldstein, Alisa M., Freedman, Neal D.

“…The role of diet in hepatocellular carcinoma (HCC) and its typical precursor, chronic liver disease (CLD), is poorly understood. Following dietary…”
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Inflated expectations: Rare-variant association analysis using public controls by Kim, Jung, Karyadi, Danielle M, Hartley, Stephen W, Zhu, Bin, Wang, Mingyi, Wu, Dongjing, Song, Lei, Armstrong, Gregory T, Bhatia, Smita, Robison, Leslie L, Yasui, Yutaka, Carter, Brian, Sampson, Joshua N, Freedman, Neal D, Goldstein, Alisa M, Mirabello, Lisa, Chanock, Stephen J, Morton, Lindsay M, Savage, Sharon A, Stewart, Douglas R

“…The use of publicly available sequencing datasets as controls (hereafter, "public controls") in studies of rare variant disease associations has great promise…”
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MicroRNA Expression Differentiates Histology and Predicts Survival of Lung Cancer by Landi, Maria Teresa, Zhao, Yingdong, Rotunno, Melissa, Koshiol, Jill, Liu, Hui, Bergen, Andrew W, Rubagotti, Maurizia, Goldstein, Alisa M, Linnoila, Ilona, Marincola, Francesco M, Tucker, Margaret A, Bertazzi, Pier Alberto, Pesatori, Angela C, Caporaso, Neil E, McShane, Lisa M, Wang, Ena

“…Purpose: The molecular drivers that determine histology in lung cancer are largely unknown. We investigated whether microRNA (miR) expression profiles can…”
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Genome wide analysis of DNA copy number neutral loss of heterozygosity (CNNLOH) and its relation to gene expression in esophageal squamous cell carcinoma by Hu, Nan, Clifford, Robert J, Yang, Howard H, Wang, Chaoyu, Goldstein, Alisa M, Ding, Ti, Taylor, Philip R, Lee, Maxwell P

“…Genomic instability plays an important role in human cancers. We previously characterized genomic instability in esophageal squamous cell carcinomas (ESCC) in…”
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A Systematic Literature Review of Whole Exome and Genome Sequencing Population Studies of Genetic Susceptibility to Cancer by Rotunno, Melissa, Barajas, Rolando, Clyne, Mindy, Hoover, Elise, Simonds, Naoko I, Lam, Tram Kim, Mechanic, Leah E, Goldstein, Alisa M, Gillanders, Elizabeth M

“…The application of next-generation sequencing (NGS) technologies in cancer research has accelerated the discovery of somatic mutations; however, progress in…”
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Genomic Landscape of Somatic Alterations in Esophageal Squamous Cell Carcinoma and Gastric Cancer by Hu, Nan, Kadota, Mitsutaka, Liu, Huaitian, Abnet, Christian C, Su, Hua, Wu, Hailong, Freedman, Neal D, Yang, Howard H, Wang, Chaoyu, Yan, Chunhua, Wang, Lemin, Gere, Sheryl, Hutchinson, Amy, Song, Guohong, Wang, Yuan, Ding, Ti, Qiao, You-Lin, Koshiol, Jill, Dawsey, Sanford M, Giffen, Carol, Goldstein, Alisa M, Taylor, Philip R, Lee, Maxwell P

“…Gastric cancer and esophageal cancer are the second and sixth leading causes of cancer-related death worldwide. Multiple genomic alterations underlying gastric…”
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Mutational signatures in 175 Chinese gastric cancer patients by Liu, Fatao, Hu, Nan, Jiang, Kewei, Liu, Huaitian, Wang, Mingyi, Hu, Ying, Zhang, Tongwu, Wu, Ho-Hsiang, Yang, Howard, Weng, Hao, Dong, Ping, Giffen, Carol, Zhu, Bin, Lee, Maxwell P, Abnet, Christian C, Taylor, Philip R, Liu, Yun, Liu, Yingbin, Goldstein, Alisa M

“…Gastric cancer (GC), a molecularly heterogeneous disease, is the third leading cause of cancer death worldwide. The majority of GC cases worldwide occur in…”
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Comparison of global gene expression of gastric cardia and noncardia cancers from a high-risk population in china by Wang, Gangshi, Hu, Nan, Yang, Howard H, Wang, Lemin, Su, Hua, Wang, Chaoyu, Clifford, Robert, Dawsey, Erica M, Li, Jian-Min, Ding, Ti, Han, Xiao-You, Giffen, Carol, Goldstein, Alisa M, Taylor, Philip R, Lee, Maxwell P

“…To profile RNA expression in gastric cancer by anatomic subsites as an initial step in identifying molecular subtypes and providing targets for early detection…”
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Chronic obstructive pulmonary disease and altered risk of lung cancer in a population-based case-control study by Koshiol, Jill, Rotunno, Melissa, Consonni, Dario, Pesatori, Angela Cecilia, De Matteis, Sara, Goldstein, Alisa M, Chaturvedi, Anil K, Wacholder, Sholom, Landi, Maria Teresa, Lubin, Jay H, Caporaso, Neil E

“…Chronic obstructive pulmonary disease (COPD) has been consistently associated with increased risk of lung cancer. However, previous studies have had limited…”
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Risk factors for esophageal and gastric cancers in Shanxi Province, China: A case–control study by Gao, Ying, Hu, Nan, Han, Xiao You, Ding, Ti, Giffen, Carol, Goldstein, Alisa M, Taylor, Philip R

“…Abstract Objective : Smoking and alcohol consumption explain little of the risk for upper-gastrointestinal (UGI) cancer in China, where over half of all cases…”
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Two newly identified genetic determinants of pigmentation in Europeans by Gudbjartsson, Daniel F, Stefansson, Kari, Sulem, Patrick, Stacey, Simon N, Helgason, Agnar, Rafnar, Thorunn, Jakobsdottir, Margret, Steinberg, Stacy, Gudjonsson, Sigurjon A, Palsson, Arnar, Thorleifsson, Gudmar, Pálsson, Snæbjörn, Sigurgeirsson, Bardur, Thorisdottir, Kristin, Ragnarsson, Rafn, Benediktsdottir, Kristrun R, Aben, Katja K, Vermeulen, Sita H, Goldstein, Alisa M, Tucker, Margaret A, Kiemeney, Lambertus A, Olafsson, Jon H, Gulcher, Jeffrey, Kong, Augustine, Thorsteinsdottir, Unnur

“…We present results from a genome-wide association study for variants associated with human pigmentation characteristics among 5,130 Icelanders, with follow-up…”
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Whole-Exome Sequencing of Nasopharyngeal Carcinoma Families Reveals Novel Variants Potentially Involved in Nasopharyngeal Carcinoma by Yu, Guoqin, Hsu, Wan-Lun, Coghill, Anna E., Yu, Kelly J., Wang, Cheng-Ping, Lou, Pei-Jen, Liu, Zhiwei, Jones, Kristie, Vogt, Aurelie, Wang, Mingyi, Mbulaiteye, Sam M., Chen, Hao-Hui, Boland, Joseph, Yeager, Meredith, Diehl, Scott R., Chen, Chien-Jen, Hildesheim, Allan, Goldstein, Alisa M.

“…Genetic susceptibility is likely involved in nasopharyngeal carcinoma (NPC), a cancer caused by Epstein-Barr virus (EBV) infection. Understanding of genetic…”
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Index-based dietary patterns and risk of head and neck cancer in a large prospective study by Li, Wen-Qing, Park, Yikyung, Wu, Jennifer W, Goldstein, Alisa M, Taylor, Philip R, Hollenbeck, Albert R, Freedman, Neal D, Abnet, Christian C

“…Background: Head and neck cancer (HNC) is the seventh most common cancer worldwide. Although diet has been proposed to play an important role in HNC, few…”
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Index-based Dietary Patterns and Risk of Esophageal and Gastric Cancer in a Large Cohort Study by Li, Wen–Qing, Park, Yikyung, Wu, Jennifer W, Ren, Jian–Song, Goldstein, Alisa M, Taylor, Philip R, Hollenbeck, Albert R, Freedman, Neal D, Abnet, Christian C

“…Background & Aims Diet could affect risk for esophageal and gastric cancers, but associations have been inconsistent. The diet is complex, so studies of…”
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ABO genotypes and the risk of esophageal and gastric cancers by Chen, Yingxi, Hu, Nan, Liao, Linda, Yu, Kai, Shu, Xiao-Ou, Zheng, Wei, Yuan, Jian-Min, Koh, Woon-Puay, Qiao, You-Lin, Fan, Jin-Hu, Dawsey, Sanford M, Freedman, Neal D, Taylor, Philip R, Goldstein, Alisa M, Abnet, Christian C

“…Blood type has been associated with the risk of gastric cancer, but few studies have examined the association with esophageal squamous cell carcinoma (ESCC)…”
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