Search Results - "Goldsmith, William T."
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ROS promote epigenetic remodeling and cardiac dysfunction in offspring following maternal engineered nanomaterial (ENM) exposure
Published in Particle and fibre toxicology (18-06-2019)“…Nano-titanium dioxide (nano-TiO ) is amongst the most widely utilized engineered nanomaterials (ENMs). However, little is known regarding the consequences…”
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2
Viable influenza A virus in airborne particles expelled during coughs versus exhalations
Published in Influenza and other respiratory viruses (01-09-2016)“…Background To prepare for a possible influenza pandemic, a better understanding of the potential for the airborne transmission of influenza from person to…”
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Maternal Engineered Nanomaterial Inhalation During Gestation Disrupts Vascular Kisspeptin Reactivity
Published in Toxicological sciences (01-06-2019)“…Abstract Maternal engineered nanomaterial (ENM) inhalation is associated with uterine vascular impairments and endocrine disruption that may lead to altered…”
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4
Transcriptomics of single dose and repeated carbon black and ozone inhalation co-exposure highlight progressive pulmonary mitochondrial dysfunction
Published in Particle and fibre toxicology (15-12-2021)“…Air pollution is a complex mixture of particles and gases, yet current regulations are based on single toxicant levels failing to consider potential…”
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5
Nano-titanium dioxide inhalation exposure during gestation drives redox dysregulation and vascular dysfunction across generations
Published in Particle and fibre toxicology (09-03-2022)“…Pregnancy is associated with many rapid biological adaptations that support healthy development of the growing fetus. One of which is critical to fetal health…”
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Oxidant-induced epithelial alarmin pathway mediates lung inflammation and functional decline following ultrafine carbon and ozone inhalation co-exposure
Published in Redox biology (01-10-2021)“…Environmental inhalation exposures are inherently mixed (gases and particles), yet regulations are still based on single toxicant exposures. While the impacts…”
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Whole-body inhalation of nano-sized carbon black: a surrogate model of military burn pit exposure
Published in BMC research notes (11-08-2022)“…Chronic multisymptom illness (CMI) is an idiopathic disease affecting thousands of U.S. Veterans exposed to open-air burn pits emitting aerosolized particulate…”
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Maternal nano-titanium dioxide inhalation exposure alters placental cyclooxygenase and oxidant balance in a sexually dimorphic manner
Published in Advances in redox research : an official journal of the Society for Redox Biology and Medicine and the Society for Free Radical Research-Europe (01-04-2024)“…•Greater impacts on redox balance in fetal female labyrinth zone (LZ) of the placenta after maternal nanomaterial inhalation exposure.•Decreased xanthine…”
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Maternal nano-titanium dioxide inhalation alters fetoplacental outcomes in a sexually dimorphic manner
Published in Frontiers in toxicology (06-03-2023)“…The placenta plays a critical role in nutrient-waste exchange between the maternal and fetal circulations, thus functioning as an interface that profoundly…”
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Respiratory Toxicologic Pathology of Inhaled Diacetyl in Sprague-Dawley Rats
Published in Toxicologic pathology (01-02-2008)“…Inhalation of butter flavoring vapors by food manufacturing workers causes an emerging lung disease clinically resembling bronchiolitis obliterans. Diacetyl,…”
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A comparison of performance metrics for cloth masks as source control devices for simulated cough and exhalation aerosols
Published in Aerosol science and technology (03-10-2021)“…Universal mask wearing is recommended to help control the spread of COVID-19. Masks reduce the expulsion of aerosols of respiratory fluids into the environment…”
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Maternal titanium dioxide nanomaterial inhalation exposure compromises placental hemodynamics
Published in Toxicology and applied pharmacology (15-03-2019)“…The fetal consequences of gestational engineered nanomaterial (ENM) exposure are unclear. The placenta is a barrier protecting the fetus and allowing transfer…”
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Nanomaterial Inhalation During Pregnancy Alters Systemic Vascular Function in a Cyclooxygenase-Dependent Manner
Published in Toxicological sciences (28-07-2022)“…Abstract Pregnancy requires rapid adaptations in the uterine microcirculation to support fetal development. Nanomaterial inhalation is associated with…”
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Evaluation of Pulmonary and Systemic Toxicity of Oil Dispersant (COREXIT EC9500A®) Following Acute Repeated Inhalation Exposure
Published in Environmental Health Insights (01-01-2014)“…Introduction Oil spill cleanup workers come into contact with numerous potentially hazardous chemicals derived from the oil spills, as well as chemicals…”
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Viable Influenza A Virus in Airborne Particles from Human Coughs
Published in Journal of occupational and environmental hygiene (01-02-2015)“…Patients with influenza release aerosol particles containing the virus into their environment. However, the importance of airborne transmission in the spread…”
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Inhalation of Stachybotrys chartarum Fragments Induces Pulmonary Arterial Remodeling
Published in American journal of respiratory cell and molecular biology (01-05-2020)“…is a fungal contaminant within the built environment and a respiratory health concern in the United States. The objective of this study was to characterize the…”
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Enhanced antioxidant capacity prevents epitranscriptomic and cardiac alterations in adult offspring gestationally-exposed to ENM
Published in Nanotoxicology (01-08-2021)“…Maternal engineered nanomaterial (ENM) exposure during gestation has been associated with negative long-term effects on cardiovascular health in progeny. Here,…”
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miRNA-378a as a key regulator of cardiovascular health following engineered nanomaterial inhalation exposure
Published in Nanotoxicology (28-05-2019)“…Nano-titanium dioxide (nano-TiO 2 ), though one of the most utilized and produced engineered nanomaterials (ENMs), diminishes cardiovascular function through…”
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Maternal Nanomaterial Inhalation Exposure: Critical Gestational Period in the Uterine Microcirculation is Angiotensin II Dependent
Published in Cardiovascular toxicology (01-02-2022)“…Maternal inhalation exposure to engineered nanomaterials (ENM) has been associated with microvascular dysfunction and adverse cardiovascular responses…”
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Vinyl Chloride and High-Fat Diet as a Model of Environment and Obesity Interaction
Published in Journal of visualized experiments (12-01-2020)“…Vinyl chloride (VC), an abundant environmental contaminant, causes steatohepatitis at high levels, but is considered safe at lower levels. Although several…”
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