Search Results - "Goldsbury, C."

Protein complexes from mouse and chick brain that interact with phospho-KXGS motif tau/microtubule associated protein antibody by Davies, D S, Arthur, A T, Aitken, H L, Crossett, B, Goldsbury, C S

“…Mouse monoclonal 12E8 antibody, which recognises conserved serine phosphorylated KXGS motifs in the microtubule binding domains of tau/tau-like microtubule…”
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ADF/Cofilin-actin rods in neurodegenerative diseases by Bamburg, J R, Bernstein, B W, Davis, R C, Flynn, K C, Goldsbury, C, Jensen, J R, Maloney, M T, Marsden, I T, Minamide, L S, Pak, C W, Shaw, A E, Whiteman, I, Wiggan, O

“…Dephosphorylation (activation) of cofilin, an actin binding protein, is stimulated by initiators of neuronal dysfunction and degeneration including oxidative…”
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Atomic Force Microscopy Reveals Defects Within Mica Supported Lipid Bilayers Induced by the Amyloidogenic Human Amylin Peptide by Green, J.D., Kreplak, L., Goldsbury, C., Li Blatter, X., Stolz, M., Cooper, G.S., Seelig, A., Kistler, J., Aebi, U.

“…To date, over 20 peptides or proteins have been identified that can form amyloid fibrils in the body and are thought to cause disease. The mechanism by which…”
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Amyloid Fibril Formation from Full-Length and Fragments of Amylin by Goldsbury, C., Goldie, K., Pellaud, J., Seelig, J., Frey, P., Müller, S.A., Kistler, J., Cooper, G.J.S., Aebi, U.

“…Amyloiddeposits of fibrillar human amylin (hA) in the pancreas may be a causative factor in type-2 diabetes. A detailed comparison of in vitro fibril formation…”
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Transthyretin fibrillogenesis entails the assembly of monomers: a molecular model for in vitro assembled transthyretin amyloid-like fibrils by Cardoso, I, Goldsbury, C S, Müller, S A, Olivieri, V, Wirtz, S, Damas, A M, Aebi, U, Saraiva, M J

“…Extracellular accumulation of transthyretin (TTR) variants in the form of fibrillar amyloid deposits is the pathological hallmark of familial amyloidotic…”
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Studies on the in Vitro Assembly of Aβ 1–40: Implications for the Search for Aβ Fibril Formation Inhibitors by Goldsbury, Claire S., Wirtz, Sabine, Müller, Shirley A., Sunderji, Shabir, Wicki, Peter, Aebi, Ueli, Frey, Peter

“…The progressive deposition of the amyloid β peptide (Aβ) in fibrillar form is a key feature in the development of the pathology in Alzheimer's disease (AD). We…”
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Polymorphic Fibrillar Assembly of Human Amylin by Goldsbury, Claire S., Cooper, Garth J.S., Goldie, Kenneth N., Müller, Shirley A., Saafi, Etuate L., Gruijters, W.T.M., Misur, Martin P., Engel, Andreas, Aebi, Ueli, Kistler, Joerg

“…Human amylin forms fibrillar amyloid between pancreatic islet cells in patients with non-insulin-dependent (type 2) diabetes mellitus. Fibrillar assemblies…”
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Multiple Assembly Pathways Underlie Amyloid-β Fibril Polymorphisms by Goldsbury, Claire, Frey, Peter, Olivieri, Vesna, Aebi, Ueli, Müller, Shirley A.

“…The amyloid β-protein transiently forms low and high molecular mass oligomers and protofibrils in vitro, and after longer incubation times assembles into…”
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Amyloid structure and assembly: Insights from scanning transmission electron microscopy by Goldsbury, Claire, Baxa, Ulrich, Simon, Martha N., Steven, Alasdair C., Engel, Andreas, Wall, Joseph S., Aebi, Ueli, Müller, Shirley A.

“…Amyloid fibrils are filamentous protein aggregates implicated in several common diseases such as Alzheimer’s disease and type II diabetes. Similar structures…”
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Watching amyloid fibrils grow by time-lapse atomic force microscopy by Goldsbury, C, Kistler, J, Aebi, U, Arvinte, T, Cooper, G J

“…Late-onset diabetes is typically associated with amyloid deposits of fibrillar amylin in the pancreatic islets. Aqueous synthetic human amylin spontaneously…”
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Human Amylin Oligomer Growth and Fibril Elongation Define Two Distinct Phases in Amyloid Formation by Green, Janelle D., Goldsbury, Claire, Kistler, Joerg, Cooper, Garth J.S., Aebi, Ueli

“…Human amylin (hA), a 37-amino-acid polypeptide, is one of a number of peptides with the ability to form amyloid fibrils and cause disease. It is the main…”
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Full-length Rat Amylin Forms Fibrils Following Substitution of Single Residues from Human Amylin by Green, Janelle, Goldsbury, Claire, Mini, Thierry, Sunderji, Shabir, Frey, Peter, Kistler, Joerg, Cooper, Garth, Aebi, Ueli

“…Pancreatic amyloid deposits, composed of the 37 amino acid residue peptide amylin, represent an integral part of type 2 diabetes mellitus pathology. Human…”
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Monitoring Biomolecular Interactions by Time-Lapse Atomic Force Microscopy by Stolz, Martin, Stoffler, Daniel, Aebi, Ueli, Goldsbury, Claire

“…The atomic force microscope (AFM) is a unique imaging tool that enables the tracking of single macromolecule events in response to physiological effectors and…”
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Visualizing the growth of Alzheimer's Aβ amyloid-like fibrils by Goldsbury, Claire, Aebi, Ueli, Frey, Peter

“…Polymerization of normally soluble, beta -sheet-forming proteins or peptides yielding fibrillar amyloid deposits is a hallmark of many neurodegenerative…”
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Heterogeneity of the glutathione transferase genes encoding enzymes responsible for insecticide degradation in the housefly by Syvanen, M. (University of California, Davis, CA.), Zhou, Z, Wharton, J, Goldsbury, C, Clark, A

“…One of the four glutathione-S-transferases (GST) that is overproduced in the insecticide-resistant Cornell-R strain of the housefly (Musca domestica) produces…”
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