Search Results - "Goldman, Jerome M"

The rodent estrous cycle: characterization of vaginal cytology and its utility in toxicological studies by Goldman, Jerome M., Murr, Ashley S., Cooper, Ralph L.

“…While an evaluation of the estrous cycle in laboratory rodents can be a useful measure of the integrity of the hypothalamic‐pituitary‐ovarian reproductive…”
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Atrazine and reproductive function: mode and mechanism of action studies by Cooper, Ralph L., Laws, Susan C., Das, Parikshit C., Narotsky, Michael G., Goldman, Jerome M., Lee Tyrey, E., Stoker, Tammy E.

“…Atrazine, a chlorotriazine herbicide, is used to control annual grasses and broadleaf weeds. In this review, we summarize our laboratory's work evaluating the…”
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The effects of prenatal exposure to atrazine on pubertal and postnatal reproductive indices in the female rat by Davis, Lori K., Murr, Ashley S., Best, Deborah S., Fraites, Melanie J.P., Zorrilla, Leah M., Narotsky, Michael G., Stoker, Tammy E., Goldman, Jerome M., Cooper, Ralph L.

“…Atrazine (ATR) is an herbicide that exerts negative reproductive effects. We examined the effects of vehicle or ATR (1, 5, 20 and 100 mg/kg-d), administered to…”
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Gestational atrazine exposure: Effects on male reproductive development and metabolite distribution in the dam, fetus, and neonate by Fraites, Melanie J.P., Narotsky, Michael G., Best, Deborah S., Stoker, Tammy E., Davis, Lori K., Goldman, Jerome M., Hotchkiss, Michelle G., Klinefelter, Gary R., Kamel, Alaa, Qian, Yaorong, Podhorniak, Lynda, Cooper, Ralph L.

“…Few studies have investigated the long-term effects of atrazine (ATR) following in utero exposure. We evaluated the effects of gestational exposure of Sprague…”
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Endocrine-Disrupting Chemicals: Prepubertal Exposures and Effects on Sexual Maturation and Thyroid Activity in the Female Rat. A Focus on the EDSTAC Recommendations by Goldman, Jerome M., Laws, Susan C., Balchak, Sharon K., Cooper, Ralph L., Kavlock, Robert J.

“…In 1996, the US Environmental Protection Agency was given a mandate by Congress to develop a screening program that would evaluate whether variously identified…”
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Reproductive toxicity of a mixture of regulated drinking-water disinfection by-products in a multigenerational rat bioassay by Narotsky, Michael G, Klinefelter, Gary R, Goldman, Jerome M, DeAngelo, Anthony B, Best, Deborah S, McDonald, Anthony, Strader, Lillian F, Murr, Ashley S, Suarez, Juan D, George, Michael H, Hunter, E Sidney, Simmons, Jane Ellen

“…Trihalomethanes (THMs) and haloacetic acids (HAAs) are regulated disinfection by-products (DBPs); their joint reproductive toxicity in drinking water is…”
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Atrazine-induced elevation or attenuation of the LH surge in the ovariectomized, estrogen-primed female rat: role of adrenal progesterone by Goldman, Jerome M, Davis, Lori K, Murr, Ashley S, Cooper, Ralph L

“…Multiple exposures to the herbicide atrazine (ATRZ) were shown to suppress the LH surge in both cycling female rats and those ovariectomized (OVX) and primed…”
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Comprehensive Assessment of a Chlorinated Drinking Water Concentrate in a Rat Multigenerational Reproductive Toxicity Study by Narotsky, Michael G, Klinefelter, Gary R, Goldman, Jerome M, Best, Deborah S, McDonald, Anthony, Strader, Lillian F, Suarez, Juan D, Murr, Ashley S, Thillainadarajah, Inthirany, Hunter, E. Sidney, Richardson, Susan D, Speth, Thomas F, Miltner, Richard J, Pressman, Jonathan G, Teuschler, Linda K, Rice, Glenn E, Moser, Virginia C, Luebke, Robert W, Simmons, Jane Ellen

“…Some epidemiological studies report associations between drinking water disinfection byproducts (DBPs) and adverse reproductive/developmental effects, e.g.,…”
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Method to assess component contribution to toxicity of complex mixtures： Assessment of puberty acquisition in rats exposed to disinfection byproducts by Parvez, Shahid, Rice, Glenn E., Teuschler, Linda K., Simmons, Jane Ellen, Speth, Thomas F., Richardson, Susan D., Miltner, Richard J., Hunter, E. Sidney, Pressman, Jonathan G., Strader, Lillian F., Klinefelter, Gary R., Goldman, Jerome M., Narotsky, Michael G.

“…A method based on regression modeling was developed to discern the contribution of component chemicals to the toxicity of highly complex, environmentally…”
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SINGLE OR GROUP HOUSING ALTERED HORMONAL PHYSIOLOGY AND AFFECTED PITUITARY AND INTERSTITIAL CELL KINETICS by NYSKA, Abraham, HESTER, Susan D., COOPER, Ralph L., GOLDMAN, Jerome M., STOKER, Tammy E., HOUSE, Dennis, WOLF, Douglas C.

“…A significant negative correlation between testicular interstitial cell tumors and pituitary tumors in control male F344 rats has been reported associated with…”
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Methoxychlor-induced alterations in the histological expression of angiogenic factors in pituitary and uterus by Goldman, Jerome M, Murr, Ashley S, Buckalew, Angela R, Schmid, Judith E, Abbott, Barbara D

“…Within the reproductive system, oestrogenic stimulation of uterine and pituitary tissue typically causes a proliferative response accompanied by an angiogenic…”
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Suppression of the Steroid-Primed Luteinizing Hormone Surge in the Female Rat by Sodium Dimethyldithiocarbamate: Relationship to Hypothalamic Catecholamines and GnRH Neuronal Activation by Goldman, Jerome M., Murr, Ashley S., Buckalew, Angela R., Cooper, Ralph L.

“…In female rodents, hypothalamic norepinephrine (NE) has a role in stimulating the secretion of gonadotropin-releasing hormone (GnRH) that triggers the…”
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Continuous Exposure to Dibromoacetic Acid Delays Pubertal Development and Compromises Sperm Quality in the Rat by Klinefelter, Gary R., Strader, Lillian F., Suarez, Juan D., Roberts, Naomi L., Goldman, Jerome M., Murr, Ashley S.

“…Previously our work on the haloacid by-products of drinking water disinfection focused on adult exposures. Herein we evaluate the consequence of continuous…”
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Reproductive functions and hypothalamic catecholamines in response to the soil fumigant metam sodium: Adaptations to extended exposures by Goldman, Jerome M, Cooper, Ralph L, Murr, Ashley S

“…Abstract Metam sodium (MS) is a soil fumigant and Category II pesticide with a relatively low toxicity in mammals. Previous data have shown an ability to…”
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Twenty-week exposures to the drinking water disinfection by-product dibromoacetic acid: reproductive cyclicity and steroid concentrations in the female Sprague–Dawley rat by Murr, Ashley S., Goldman, Jerome M.

“…Elevated gavage exposures to the drinking water disinfection by-product dibromoacetic acid (DBA) have been found to disrupt estrous cyclicity in the rat and…”
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Moderating influence of the drinking water disinfection by-product dibromoacetic acid on a dithiocarbamate-induced suppression of the luteinizing hormone surge in female rats by Goldman, Jerome M., Murr, Ashley S., Buckalew, Angela R., Ferrell, Janet M., Cooper, Ralph L.

“…The disinfection by-product dibromoacetic acid (DBA) has been found in female rats to increase circulating concentrations of both estradiol (E2) and estrone…”
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Alterations in ovarian follicular progesterone secretion by elevated exposures to the drinking water disinfection by-product dibromoacetic acid: examination of the potential site(s) of impact along the steroidogenic pathway by Goldman, Jerome M, Murr, Ashley S

“…Previous data from our laboratory indicated that the drinking water disinfection by-product, dibromoacetic acid (DBA), when applied in vitro to rat…”
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Dibromoacetic acid-induced elevations in circulating estradiol: effects in both cycling and ovariectomized/steroid-primed female rats by Goldman, Jerome M., Murr, Ashley S.

“…Oral exposures to high concentrations of the drinking water disinfection by-product dibromoacetic acid (DBA) over the course of 14 days have been found to…”
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Rat Epididymal Sperm Quantity, Quality, and Transit Time after Guanethidine-Induced Sympathectomy by Kempinas, W D, Suarez, J D, Roberts, N L, Strader, L, Ferrell, J, Goldman, J M, Klinefelter, G R

“…Guanethidine, a chemical that selectively abolishes peripheral noradrenergic nerves, was used to investigate the role of sympathetic innervation in the…”
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Effect of atrazine on ovarian function in the rat by Cooper, Ralph L., Stoker, Tammy E., Goldman, Jerome M., Parrish, Michelle B., Tyrey, Lee

“…The effect of the chlorotriazine herbicide, atrazine, on ovarian function was studied in Long-Evans hooded (LE-hooded) and Sprague-Dawley (SD) rats. Atrazine…”
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