Search Results - "Golding, Leonard A. R."

Implantable Continuous-Flow Right Ventricular Assist Device: Lessons Learned in the Development of a Cleveland Clinic Device by Fukamachi, Kiyotaka, MD, PhD, Shiose, Akira, MD, PhD, Massiello, Alex L., MEBME, Horvath, David J., MSME, Golding, Leonard A.R., MBBS, FRACS, Lee, Sangjin, MD, Starling, Randall C., MD, MPH

“…Although the need for right ventricular assist device (RVAD) support for right ventricular failure after the implantation of a continuous-flow left ventricular…”
Get full text

Speed Modulation of the Continuous-Flow Total Artificial Heart to Simulate a Physiologic Arterial Pressure Waveform by Shiose, Akira, Nowak, Kathleen, Horvath, David J, Massiello, Alex L, Golding, Leonard A. R, Fukamachi, Kiyotaka

“…This study demonstrated the concept of using speed modulation in a continuous-flow total artificial heart (CFTAH) to shape arterial pressure waveforms and to…”
Get full text

Results of the European Clinical Trial of Arrow CorAide Left Ventricular Assist System by Saeed, Diyar, Arusoglu, Latif, Gazzoli, Fabrizio, Hetzer, Roland, Morshius, Michael, Alloni, Alessia, Viganò, Mario, Koerfer, Reiner, Golding, Leonard A. R., El Banayosy, Aly

“…The aim of this study was to evaluate the safety and performance of the Arrow CorAide left ventricular assist system (LVAS) (Arrow International, Reading, PA,…”
Get full text

Post-explant visualization of thrombi in outflow grafts and their junction to a continuous-flow total artificial heart using a high-definition miniaturized camera by Karimov, Jamshid H., Horvath, David, Sunagawa, Gengo, Byram, Nicole, Moazami, Nader, Golding, Leonard A. R., Fukamachi, Kiyotaka

“…Post-explant evaluation of the continuous-flow total artificial heart in preclinical studies can be extremely challenging because of the device’s unique…”
Get full text

Anatomy of the bovine ascending aorta and brachiocephalic artery found unfavorable for total artificial heart implant by Karimov, Jamshid H., Sunagawa, Gengo, Such, Kimberly A., Sale, Shiva, Golding, Leonard A. R., Moazami, Nader, Fukamachi, Kiyotaka

“…The biocompatibility assessment of the Cleveland Clinic continuous-flow total artificial heart is an important part of the device developmental program…”
Get full text

Mechanism of Self‐Regulation and In Vivo Performance of the Cleveland Clinic Continuous‐Flow Total Artificial Heart by Horvath, David, Byram, Nicole, Karimov, Jamshid H., Kuban, Barry, Sunagawa, Gengo, Golding, Leonard A.R., Moazami, Nader, Fukamachi, Kiyotaka

“…Cleveland Clinic's continuous‐flow total artificial heart (CFTAH) provides systemic and pulmonary circulations using one assembly (one motor, two impellers)…”
Get full text

Reduced Pulsatility Induces Periarteritis in Kidney: Role of the Local Renin–Angiotensin System by Ootaki, Chiyo, MD, Yamashita, Michifumi, MD, PhD, Ootaki, Yoshio, MD, PhD, Kamohara, Keiji, MD, Weber, Stephan, Dipl Ing, Klatte, Ryan S., BSBME, Smith, William A., DEng, PE, Massiello, Alex L., MEBME, Emancipator, Steven N., MD, Golding, Leonard A.R., MD, Fukamachi, Kiyotaka, MD, PhD

“…Objective The need for pulsatility in the circulation during long-term mechanical support has been a subject of debate. We compared histologic changes in calf…”
Get full text

Thrombotic Depositions on Right Impeller of Double‐Ended Centrifugal Total Artificial Heart In Vivo by Karimov, Jamshid H., Horvath, David J., Okano, Shinji, Goodin, Mark, Sunagawa, Gengo, Byram, Nicole, Moazami, Nader, Golding, Leonard A.R., Fukamachi, Kiyotaka

“…The development of total artificial heart devices is a complex undertaking that includes chronic biocompatibility assessment of the device. It is considered…”
Get full text

Median Sternotomy or Right Thoracotomy Techniques for Total Artificial Heart Implantation in Calves by Karimov, Jamshid H., Moazami, Nader, Sunagawa, Gengo, Kobayashi, Mariko, Byram, Nicole, Sale, Shiva, Such, Kimberly A., Horvath, David J., Golding, Leonard A.R., Fukamachi, Kiyotaka

“…The choice of optimal operative access technique for mechanical circulatory support device implantation ensures successful postoperative outcomes. In this…”
Get full text

Deairing Techniques for Double‐Ended Centrifugal Total Artificial Heart Implantation by Karimov, Jamshid H., Horvath, David J., Byram, Nicole, Sunagawa, Gengo, Grady, Patrick, Sinkewich, Martin, Moazami, Nader, Sale, Shiva, Golding, Leonard A.R., Fukamachi, Kiyotaka

“…The unique device architecture of the Cleveland Clinic continuous‐flow total artificial heart (CFTAH) requires dedicated and specific air‐removal techniques…”
Get full text

Progress on the Design and Development of the Continuous-Flow Total Artificial Heart by Kobayashi, Mariko, Horvath, David J., Mielke, Nicole, Shiose, Akira, Kuban, Barry, Goodin, Mark, Fukamachi, Kiyotaka, Golding, Leonard A.R.

“…Cleveland Clinic's continuous‐flow total artificial heart has one motor and one rotating assembly supported by a hydrodynamic bearing. The right hydraulic…”
Get full text

Double-wire sternal closure technique in bovine animal models for total artificial heart implant by Karimov, Jamshid H, Sunagawa, Gengo, Golding, Leonard A R, Moazami, Nader, Fukamachi, Kiyotaka

“…In vivo preclinical testing of mechanical circulatory devices requires large animal models that provide reliable physiological and hemodynamic conditions by…”
Get full text

First report of 90-day support of 2 calves with a continuous-flow total artificial heart by Karimov, Jamshid H., MD, PhD, Moazami, Nader, MD, Kobayashi, Mariko, MD, Sale, Shiva, MD, Such, Kimberly, DVM, Byram, Nicole, BS, Sunagawa, Gengo, MD, Horvath, David, MSME, Gao, Shengqiang, PhD, Kuban, Barry, BS, Golding, Leonard A.R., MB, BS, FRACS, Fukamachi, Kiyotaka, MD, PhD

“…Abstract Objective The Cleveland Clinic continuous-flow total artificial heart (CFTAH) is a compact, single-piece, valveless, pulsatile pump providing…”
Get full text

In Vivo Biocompatibility Evaluation of a New Resilient, Hard-Carbon, Thin-Film Coating for Ventricular Assist Devices by Takaseya, Tohru, Fumoto, Hideyuki, Shiose, Akira, Arakawa, Yoko, Rao, Santosh, Horvath, David J., Massiello, Alex L., Mielke, Nicole, Chen, Ji-Feng, Zhou, Qun, Dessoffy, Raymond, Kramer, Larry, Benefit, Stephen, Golding, Leonard A.R., Fukamachi, Kiyotaka

“…The purpose of this study was to evaluate in vivo the biocompatibility of BioMedFlex (BMF), a new resilient, hard‐carbon, thin‐film coating, as a blood journal…”
Get full text

Use of Zirconia Ceramic in the DexAide Right Ventricular Assist Device Journal Bearing by Saeed, Diyar, Horvath, David J., Massiello, Alex L., Ootaki, Yoshio, Benefit, Stephen, Golding, Leonard A.R., Fukamachi, Kiyotaka

“…Our aim was to evaluate the potential use of zirconium oxide (zirconia) as a blood journal bearing material in the DexAide right ventricular assist device. The…”
Get full text

Median Sternotomy Approach for Chronic Bovine Experiments by Saeed, Diyar, Zahr, Roula, Shalli, Shanaz, Fumoto, Hideyuki, Horai, Tetsuya, Anzai, Tomohiro, Arakawa, Yoko, Dessoffy, Raymond, Catanese, Jacquelyn, Golding, Leonard A. R, Fukamachi, Kiyotaka

“…Lateral thoracotomy is the traditional surgical approach for preclinical animal testing of various ventricular assist devices. Median sternotomy, however, is…”
Get full text

In Vivo Evaluation of Zirconia Ceramic in the DexAide Right Ventricular Assist Device Journal Bearing by Saeed, Diyar, Shalli, Shanaz, Fumoto, Hideyuki, Ootaki, Yoshio, Horai, Tetsuya, Anzai, Tomohiro, Zahr, Roula, Horvath, David J., Massiello, Alex L., Chen, Ji-Feng, Dessoffy, Raymond, Catanese, Jacquelyn, Benefit, Stephen, Golding, Leonard A.R., Fukamachi, Kiyotaka

“…Zirconia is a ceramic with material properties ideal for journal bearing applications. The purpose of this study was to evaluate the use of zirconium oxide…”
Get full text

Preload Sensitivity in Cardiac Assist Devices by Fukamachi, Kiyotaka, MD, PhD, Shiose, Akira, MD, PhD, Massiello, Alex, MEBME, Horvath, David J., MSME, Golding, Leonard A.R., MB, BS, Lee, Sangjin, MD, Starling, Randall C., MD, MPH

“…With implantable cardiac assist devices increasingly proving their effectiveness as therapeutic options for end-stage heart failure, it is important for…”
Get full text

Human Clinical Fitting Study of the DexAide Right Ventricular Assist Device by Ootaki, Yoshio, Ootaki, Chiyo, Massiello, Alex, Horvath, David, Chen, Ji-Feng, Mihaljevic, Tomislav, Navia, Jose L., Smedira, Nicholas G., Golding, Leonard A.R., Fukamachi, Kiyotaka

“…The DexAide right ventricular assist device (RVAD) has been developed as an implantable RVAD. The purpose of this study was to determine the final design and…”
Get full text

Human Fitting Studies of Cleveland Clinic Continuous-Flow Total Artificial Heart by Karimov, Jamshid H, Steffen, Robert J, Byram, Nicole, Sunagawa, Gengo, Horvath, David, Cruz, Vincent, Golding, Leonard A R, Fukamachi, Kiyotaka, Moazami, Nader

“…Implantation of mechanical circulatory support devices is challenging, especially in patients with a small chest cavity. We evaluated how well the Cleveland…”
Get full text